Assay for detecting tuberculosis in nonhuman primates
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United States of America Patent
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Mar 6, 2012
Grant Date -
Mar 16, 2006
app pub date -
Aug 26, 2005
filing date -
Aug 26, 2004
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Abstract
Systems, methods, and compositions for a diagnostic method for detecting TB in non-human primates that is easy to use, sensitive, and specific. The method utilizes recombinant mycobacterial antigens, such as polyfusion proteins. The method utilizes an antigen-antibody-antigen arrangement to detect TB infection in nonhuman primates. The method can detect IgM antibodies to TB, in addition to IgG antibodies, providing ability to detect TB earlier in nonhuman primate TB infection as compared to conventional TB tests.
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