Microorganisms for the production of 1,4-butanediol and related methods
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United States of America Patent
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Mar 6, 2012
Grant Date -
Feb 24, 2011
app pub date -
Jun 4, 2010
filing date -
Jun 4, 2009
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Abstract
The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO and further optimized for expression of BDO. The invention additionally provides methods of using such microbial organisms to produce BDO.
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