US Patent No: 8,133,865

Number of patents in Portfolio can not be more than 2000

von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage

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Abstract

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The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BAXALTA GMBHOPFIKON, CH282
BAXALTA INCORPORATEDBANNOCKBURN, IL282
NEKTAR THERAPEUTICSSAN CARLOS, CA324

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bossard, Mary J Madison, US 61 302
Fang, Zhihao Madison, US 35 225
Gritsch, Herbert Vienna, AT 10 79
Mitchell, Stacy Madison, US 6 77
Scheiflinger, Friedrich Vienna, AT 74 193
Siekmann, Juergen Vienna, AT 52 145
Stephenson, Gayle Decatur, US 15 51
Turecek, Peter Klosterneuburg, AT 130 640
Varadi, Katalin Vienna, AT 20 69
Zappe, Harold Harvest, US 12 17
Zhang, Ping Madison, US 120 311

Cited Art Landscape

Patent Info (Count) # Cites Year
 
PHARMACIA & UPJOHN (1)
6,048,720 Conjugates of a polypeptide and a biocompatible polymer 92 1998
 
POLICAPPELLI, NINI E. (1)
5,612,039 Dietary supplement 38 1995
 
ENZON, INC. (6)
* 5,122,614 Active carbonates of polyalkylene oxides for modification of polypeptides 359 1990
* 5,298,643 Aryl imidate activated polyalkylene oxides 77 1992
* 5,621,039 Factor IX- polymeric conjugates 98 1993
5,637,749 Aryl imidate activated polyalkylene oxides 97 1995
5,969,040 Factor IX -- polymeric conjugates 113 1996
6,566,506 Non-antigenic branched polymer conjugates 24 2000
 
NEKTAR THERAPEUTICS (8)
5,629,384 Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces 146 1994
5,932,462 Multiarmed, monofunctional, polymer for coupling to molecules and surfaces 474 1995
6,362,254 Poly(ethylene glycol) derivatives with proximal reactive groups 136 1999
6,514,491 Hydrolytically degradable carbamate derivatives of poly(ethylene glycol) 14 2001
* 7,199,223 Polymer-factor VIII moiety conjugates 70 2004
7,060,259 Hydrolytically degradable carbamate derivatives of poly(ethylene glycol) 10 2005
2006/0293,499 Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates 14 2006
2008/0058,504 Polymer-factor VIII moiety conjugates 11 2007
 
Xencor, Inc. (1)
2005/0079,155 Generating protein pro-drugs using reversible PPG linkages 12 2004
 
NOVO NORDISK A/S (1)
7,125,843 Glycoconjugates including more than one peptide 56 2003
 
FUJI PHOTO FILM CO., LTD. (1)
4,510,233 Antistatic agent containing silver halide photographic light-sensitive materials 16 1983
 
YEDA RESEARCH AND DEVELOPMENT CO. LTD. (2)
2007/0027,073 Long-acting derivatives of pyy agonists 14 2004
2006/0171,920 Reversible pegylated drugs 56 2005
 
GRIFOLS INC. (1)
* 6,037,452 Poly(alkylene oxide)-Factor VIII or Factor IX conjugate 99 1992
 
BAXALTA INCORPORATED (1)
* 7,884,075 Polymer-factor VIII-von Willebrand factor-conjugates 5 2005
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
BAXTER INTERNATIONAL INC. (1)
* 2010/0121,028 Hydrolysable Polymeric FMOC- Linker 0 2010
* Cited By Examiner

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