US Patent No: 8,133,865

Number of patents in Portfolio can not be more than 2000

von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage

ALSO PUBLISHED AS: 20080234193

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Abstract

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The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BAXTER HEALTHCARE S.A.DEERFIELD, IL613
BAXTER INTERNATIONAL INC.DEERFIELD, IL1758
NEKTAR THERAPEUTICSSAN CARLOS, CA257

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bossard, Mary J Madison, AL 84 128
Fang, Zhihao Madison, AL 56 137
Gritsch, Herbert Vienna, AT 15 51
Mitchell, Stacy Madison, AL 11 18
Scheiflinger, Friedrich Vienna, AT 96 133
Siekmann, Juergen Vienna, AT 76 86
Stephenson, Gayle Madison, AL 21 13
Turecek, Peter Vienna, AT 172 480
Varadi, Katalin Vienna, AT 28 44
Zappe, Harold Harvest, AL 16 5
Zhang, Ping Peoria, IL 138 171

Cited Art Landscape

Patent Info (Count) # Cites Year
 
NEKTAR THERAPEUTICS (8)
5,629,384 Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces 108 1994
5,932,462 Multiarmed, monofunctional, polymer for coupling to molecules and surfaces 391 1995
6,362,254 Poly(ethylene glycol) derivatives with proximal reactive groups 108 1999
6,514,491 Hydrolytically degradable carbamate derivatives of poly(ethylene glycol) 11 2001
7,199,223 Polymer-factor VIII moiety conjugates 52 2004
7,060,259 Hydrolytically degradable carbamate derivatives of poly(ethylene glycol) 9 2005
2006/0293,499 Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates 11 2006
2008/0058,504 Polymer-factor VIII moiety conjugates 10 2007
 
ENZON, INC. (6)
5,122,614 Active carbonates of polyalkylene oxides for modification of polypeptides 316 1990
5,298,643 Aryl imidate activated polyalkylene oxides 68 1992
5,621,039 Factor IX- polymeric conjugates 81 1993
5,637,749 Aryl imidate activated polyalkylene oxides 87 1995
5,969,040 Factor IX -- polymeric conjugates 96 1996
6,566,506 Non-antigenic branched polymer conjugates 19 2000
 
YEDA RESEARCH AND DEVELOPMENT CO. LTD. (2)
2007/0027,073 Long-acting derivatives of pyy agonists 11 2004
2006/0171,920 Reversible pegylated drugs 31 2005
 
BAXTER INTERNATIONAL INC. (1)
7,884,075 Polymer-factor VIII-von Willebrand factor-conjugates 4 2005
 
FUJI PHOTO FILM CO., LTD. (1)
4,510,233 Antistatic agent containing silver halide photographic light-sensitive materials 13 1983
 
GRIFOLS INC. (1)
6,037,452 Poly(alkylene oxide)-Factor VIII or Factor IX conjugate 82 1992
 
NOVO NORDISK A/S (1)
7,125,843 Glycoconjugates including more than one peptide 42 2003
 
PHARMACIA & UPJOHN (1)
6,048,720 Conjugates of a polypeptide and a biocompatible polymer 69 1998
 
POLICAPPELLI, NINI E. (1)
5,612,039 Dietary supplement 38 1995
 
XENCOR, INC. (1)
2005/0079,155 Generating protein pro-drugs using reversible PPG linkages 9 2004

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