Compositions and methods for therapy for diseases characterized by defective chloride transport
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United States of America Patent
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Mar 20, 2012
Grant Date -
Nov 11, 2010
app pub date -
Mar 11, 2010
filing date -
Oct 16, 1997
priority date (Note) -
Expired
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Abstract
Compositions and methods for therapy of cystic fibrosis, asthma, and other conditions characterized by defective chloride transport are provided. The compositions comprise one or more compounds such as flavones and/or isoflavones, ascorbate and/or derivatives thereof capable of stimulating chloride transport in epithelial tissues. Therapeutic methods involve the administration (e.g., orally or via inhalation) of such compositions to a patient afflicted with cystic fibrosis, asthma, and/or another condition responsive to stimulation of chloride transport.
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