US Patent No: 8,142,503

Number of patents in Portfolio can not be more than 2000

Devices and methods for facilitating controlled bone growth or repair

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Abstract

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Bone implantable devices and methodologies permit careful application of biologically active substances and management of bone growth processes. The device includes a body defining a carrier receiving area for locating adjacent bone. Carrier material is located in the carrier receiving area. Substance is delivered onto carrier material through a port. A pathway delivers substance from the carrier receiving area to the bone surface. The body may be in the form of a spinal fusion cage, facet fusion screw, artificial joint, bone fixation plate, interbody graft, IM nail, hip stem, or other bone-to-bone appliances or bone-to-device appliances. In use, carrier is installed in the carrier receiving area of the device. The device is then implanted adjacent a bone. The substance is applied to the carrier for subsequent delivery to the bone. By doping carrier material after device implantation, inadvertent contact of the substance with non-target bone is more easily eliminated.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
DEPUY SPINE, INC.RAYNHAM, MA245

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Malone, David G Jenks, US 7 602

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (14)
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6,093,207 Middle expanded, removable intervertebral disk stabilizer disk 196 1994
5,607,424 Domed cage 149 1995
5,693,100 Middle expandable intervertebral disk implant 325 1996
5,800,550 Interbody fusion cage 376 1997
5,980,522 Expandable spinal implants 368 1997
6,066,175 Fusion stabilization chamber 284 1998
5,928,284 Disc replacement prosthesis 325 1998
* 6,605,089 Apparatus and method for the delivery of electrical current for interbody spinal arthrodesis 61 1999
6,217,579 Expandable spinal implants 112 1999
6,432,140 Intervertebral retrieval device 127 2000
2002/0169,507 Interbody spine fusion cage 12 2000
6,613,084 Stent having cover with drug delivery capability 79 2001
6,926,737 Spinal fusion apparatus and method 56 2002
 
PICHA, GEORGE J. (3)
5,876,457 Spinal implant 91 1997
6,071,310 Spinal implant 89 1998
6,346,122 Spinal implant 22 1999
 
Kowmedica Osteonics Corp. (1)
6,902,581 Apparatus for fusing adjacent bone structure 45 2001
 
ALEXZA PHARMACEUTICALS, INC. (1)
6,776,978 Delivery of opioids through an inhalation route 75 2002
 
ZIMMER GMBH (1)
6,527,805 Intervertebral implant 19 2000
 
HOWMEDICA OSTEONICS CORP. (15)
4,961,740 V-thread fusion cage and method of fusing a bone joint 749 1988
5,026,373 Surgical method and apparatus for fusing adjacent bone structures 633 1989
5,055,104 Surgically implanting threaded fusion cages between adjacent low-back vertebrae by an anterior approach 589 1989
5,766,252 Interbody spinal prosthetic implant and method 536 1995
5,766,253 Spinal fusion device 220 1996
5,906,616 Conically shaped anterior fusion cage and method of implantation 186 1997
6,102,948 Spinal fusion device 137 1997
6,126,688 Apparatus for fusion of adjacent bone structures 45 1998
6,783,545 Low profile fusion cage and insertion set 10 2000
6,436,141 Apparatus for fusing adjacent bone structures 18 2001
2002/0116,064 Apparatus for fusing adjacent bone structures 16 2001
* 2002/0138,147 Apparatus for fusing adjacent bone structures 11 2001
6,726,722 Threaded apparatus for fusing adjacent bone structure 32 2001
2003/0114,854 Conically shaped anterior fusion cage and method of implantation 14 2003
7,608,105 Methods of inserting conically-shaped fusion cages 15 2005
 
Sofamor S.N.C. (1)
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OSTEOTECH, INC. (1)
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Schweiger Industries, Inc. (1)
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Movdice Holding, Inc. (2)
6,852,129 Adjustable bone fusion implant and method 227 2003
6,863,673 Methods for adjustable bone fusion implants 268 2003
 
BRANTIGAN, W. JOHN DR.( CREIGHTON UNIVERSITY SCHOOL OF MEDICINE) (1)
4,834,757 Prosthetic implant 946 1988
 
LIFENET HEALTH (1)
* 6,902,578 Composite bone graft, method of making and using same 78 2000
 
OSTEOIMPLANT TECHNOLOGY, INC. (1)
2002/0040,243 Method and apparatus for providing proper vertebral spacing 83 2001
 
Synthesis (U.S.A.) (1)
5,888,224 Implant for intervertebral space 411 1997
 
SYNTHES (U.S.A.) (1)
2005/0090,901 Intervertebral disk prosthesis or nucleus replacement prosthesis 108 2004
 
NUVASIVE, INC. (2)
D530423 Intervertebral implant 64 2005
D594986 Intervertebral implant 43 2008
 
SPINAL INNOVATIONS, L.L.C. (1)
5,976,187 Fusion implant 176 1997
 
minSURG International, Inc. (1)
2006/0111,782 Spinal plug for a minimally invasive facet joint fusion system 99 2005
 
SPINAL DYNAMICS CORPORATION (1)
2002/0035,400 Implantable joint prosthesis 208 2001
 
WARSAW ORTHOPEDIC, INC. (38)
* 5,015,247 Threaded spinal implant 1043 1988
* D377095 Interbody spinal implant 67 1994
5,593,409 Interbody spinal fusion implants 599 1995
5,782,919 Interbody fusion device and method for restoration of normal spinal anatomy 346 1995
5,609,635 Lordotic interbody spinal fusion implants 724 1995
5,785,710 Interbody spinal fusion implants 273 1995
7,452,359 Apparatus for inserting spinal implants 54 1995
5,984,967 Osteogenic fusion devices 234 1996
5,860,973 Translateral spinal implant 484 1996
* 5,846,484 Pressure flow system and method for treating a fluid permeable workpiece such as a bone 108 1997
5,776,199 Artificial spinal fusion implants 425 1997
6,039,762 Reinforced bone graft substitutes 273 1997
5,888,222 Intervertebral spacers 168 1997
5,989,289 Bone grafts 234 1997
6,206,922 Methods and instruments for interbody fusion 286 1998
6,149,650 Threaded spinal implant 90 1998
6,264,656 Threaded spinal implant 226 1998
6,241,770 Interbody spinal fusion implant having an anatomically conformed trailing end 150 1999
6,277,149 Ramp-shaped intervertebral implant 324 1999
6,645,206 Interbody fusion device and method for restoration of normal spinal anatomy 57 2000
6,821,298 Anterior expandable spinal fusion cage system 185 2000
6,558,423 Interbody spinal fusion implants with multi-lock for locking opposed screws 244 2000
6,758,849 Interbody spinal fusion implants 94 2000
7,537,616 Impacted orthopedic bone support implant 15 2000
* 6,454,807 Articulated expandable spinal fusion cage system 169 2000
2001/0010,020 Interbody spinal fusion implant having an anatomically conformed trailing end 19 2001
2002/0138,144 Threaded frusto-conical interbody spinal fusion implants 23 2002
6,923,830 Spinal fusion implant having deployable bone engaging projections 82 2002
* 6,890,355 Artificial contoured spinal fusion implants made of a material other than bone 112 2002
* 6,835,206 Anterior expandable spinal fusion cage system 216 2002
2003/0009,222 Synthetic threaded vertebral implant 10 2002
7,288,093 Spinal fusion implant having a curved end 104 2002
2003/0139,816 Threaded spinal implant for insertion between vertebral bodies 33 2003
2004/0064,185 Interbody spinal fusion implant having a reduced width and an anatomically conformed trailing end 21 2003
2004/0133,277 Spinal implant for insertion between vertebral bodies 29 2003
2005/0038,513 Apparatus for inserting nested interbody spinal fusion implants 44 2004
7,828,800 Threaded frusto-conical interbody spinal fusion implants 16 2009
7,985,258 Methods and instruments for interbody fusion 23 2009
 
INTEGRA LIFESCIENCES CORPORATION (1)
6,168,631 Subtalar implant system and method for insertion and removal 34 1997
 
SYNTHES USA, LLC (3)
6,059,829 Intervertebral implant 203 1996
5,888,228 Intervertebral implant with cage and rotating element 144 1998
2006/0064,099 Articular facet interference screw 64 2005
 
VILEX, INC. (1)
2007/0173,954 Subtalar implant and methods of use thereof 11 2006
 
George J. Picha (1)
2002/0040,242 Spinal implant 17 2001
 
EBI, LLC (2)
6,074,423 Safer more X-ray transparent spinal implant 41 1998
6,375,681 Vertebral body replacement 138 1999
 
NEXGEN SPINE, LLC (1)
2005/0015,150 Intervertebral disk and nucleus prosthesis 76 2004
 
RTI SURGICAL, INC. (2)
* D461248 Assembled bone implants 14 2000
7,182,781 Cervical tapered dowel 25 2000
 
R&B SURGICAL SOLUTIONS, LTD. (1)
5,888,223 Anterior stabilization device 357 1998
 
GERRRASPINE A.G. (1)
* 2005/0049,705 Facet implant 155 2003
 
SULZER CARBOMEDICS INC. (1)
2003/0114,930 Apparatus and method to stabilize and repair an intervertebral disc 36 2001
 
RAYMEDICA, LLC (1)
6,022,376 Percutaneous prosthetic spinal disc nucleus and method of manufacture 434 1998
 
SPINEFRONTIER INC (1)
6,371,986 Spinal fusion device, bone joining implant, and vertebral fusion implant 63 1998
 
ZIMMER SPINE, INC. (13)
5,489,308 Spinal implant 532 1994
5,709,683 Interbody bone implant having conjoining stabilization features for bony fusion 174 1995
5,609,636 Spinal implant 502 1996
6,149,686 Threaded spinal implant with bone ingrowth openings 88 1996
6,120,506 Lordotic spinal implant 156 1997
5,885,287 Self-tapping interbody bone implant 60 1997
6,010,502 Method and apparatus for conjoining bone bodies 140 1997
6,165,219 Lordotic spinal implant 49 1998
6,183,517 Expandable intervertebral fusion implant and applicator 138 1998
6,287,343 Threaded spinal implant with bone ingrowth openings 72 1999
6,391,058 Threaded spinal implant with convex trailing surface 82 1999
2002/0183,846 Spinal implant 27 2002
7,806,932 Spinal implant 23 2003
 
SDGI HILDINGS, INC. (1)
6,758,862 Vertebral body and disc space replacement devices 58 2002
 
ASAHI KOGAKU KOGYO KABUSHIKI KAISHA (2)
5,534,031 Prosthesis for spanning a space formed upon removal of an intervertebral disk 205 1994
5,776,196 Prosthesis for spanning a space formed upon removal of an intervertebral disk 193 1996
 
W. L. GORE & ASSOCIATES, INC. (1)
6,409,764 Methods and articles for regenerating bone or peridontal tissue 74 1998
 
KENSEY NASH CORPORATION (1)
5,683,459 Method and apparatus for biodegradable, osteogenic, bone graft substitute device 62 1994
 
SDGI HOLDINGS, INC. (6)
5,669,909 Interbody fusion device and method for restoration of normal spinal anatomy 515 1995
5,702,449 Reinforced porous spinal implants 458 1995
5,776,197 Adjustable vertebral body replacement 146 1996
6,375,655 Interbody fusion device and method for restoration of normal spinal anatomy 81 2000
* 6,613,091 Spinal fusion implants and tools for insertion and revision 172 2000
6,471,724 Methods and instruments for interbody fusion 175 2001
 
ORTHOPEDIC DEVELOPMENT CORPORATION (1)
2006/0111,779 Minimally invasive facet joint fusion 123 2004
 
VIA SPECIAL PURPOSE CORPORATION (1)
7,238,203 Bioactive spinal implants and method of manufacture thereof 200 2002
 
THOMPSON MIS, LLC (1)
7,824,427 Minimally invasive interbody device 16 2007
 
Heinrich Ulrich (1)
6,015,436 Implant for filling a space between vertebrae 252 1998
 
ENCORE MEDICAL ASSET CORPORATION (1)
5,683,394 Fusion mass constrainer 231 1995
 
STRYKER SPINE (1)
6,808,538 Vertebral body spacer having variable wedged endplates 67 2002
 
FACET SOLUTIONS, INC. (1)
* 2005/0080,486 Facet joint replacement 77 2003
 
BIEDERMANN TECHNOLOGIES GMBH & CO. KG (1)
6,200,348 Spacer with adjustable axial length 155 1999
 
HAN, JUNG SOO (1)
6,428,575 Prosthetic cage for spine 62 2001
 
ADVANCED TECHNICAL FABRICATION (1)
5,683,463 Intersomatic vertebral column implant 218 1994
 
DARRELL C. BRETT, M.D., P.C. (1)
* 6,409,766 Collapsible and expandable interbody fusion device 258 2000
 
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (1)
6,283,998 Alloplastic vertebral disk replacement 46 1999
 
SCIENT'X (1)
6,235,059 Intersomatic setting and fusion system 270 1998
 
ULRICH GMBH & CO. KG (1)
5,571,192 Prosthetic vertebral implant 384 1995
 
BONUTTI SKELETAL INNOVATIONS LLC (1)
* 6,099,531 Changing relationship between bones 301 1998
 
SPINEOLOGY, INC. (1)
* 5,571,189 Expandable fabric implant for stabilizing the spinal motion segment 708 1994
 
DEPUY SPINE, INC. (1)
2007/0083,265 Devices and methods for facilitating controlled bone growth or repair 74 2006
 
LDR HOLDING CORPORATION (1)
6,447,546 Apparatus and method for fusing opposing spinal vertebrae 193 2000
 
PEARL TECHNOLOGY HOLDINGS, LLC (1)
6,482,234 Prosthetic spinal disc 133 2000
 
ANOVA CORPORATION (2)
* 6,419,704 Artificial intervertebral disc replacement methods and apparatus 505 1999
2004/0172,019 Reinforcers for artificial disc replacement methods and apparatus 13 2002
 
STRYKER EUROPEAN HOLDINGS I, LLC (3)
6,855,168 Intersomatic implants in two parts 52 2002
6,824,564 Two-part intersomatic implant 98 2002
7,056,341 Two part intersomatic implant 30 2002
 
CERAMTEC AG INNOVATIVE CERAMIC ENGINEERING (1)
5,968,099 Fixation of a tibial part on a tibial plate of a knee-joint endoprosthesis 26 1998
 
SOFAMOR DANEK GROUP, INC. (1)
6,447,547 Artificial spinal fusion implants 237 2000
 
DEPUY MOTION SARL (1)
2008/0154,374 JOINT IMPLANT AND A SURGICAL METHOD ASSOCIATED THEREWITH 25 2007
 
ARTOS MEDIZINISCHE PRODUKTE GMBH (1)
5,755,798 Intervertebral implant 125 1996
 
SPINAL IMPLANT INNOVATIONS LLC (1)
6,179,873 Intervertebral implant, process for widening and instruments for implanting an intervertebral implant 237 1998
 
DEPUY ACROMED, INC. (3)
6,432,106 Anterior lumbar interbody fusion cage with locking plate 253 1999
6,569,201 Hybrid composite interbody fusion device 135 2001
6,776,798 Spacer assembly for use in spinal surgeries having end cap which includes serrated surface 60 2002
 
SPINE-TECH, INC. (1)
4,501,269 Process for fusing bone joints 667 1984
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
9,451,986 Percutaneous sacroiliac joint implant and method for surgically inserting and securing the implant into the sacroiliac joint 0 2013
 
MOXIMED, INC. (1)
* 2010/0198,354 METHOD AND SYSTEM FOR PATELLA TENDON REALIGNMENT 5 2008
 
DEPUY SYNTHES PRODUCTS, LLC (4)
8,894,685 Facet fixation and fusion screw and washer assembly and method of use 3 2007
* 8,617,246 Devices and methods for facilitating controlled bone growth or repair 2 2010
8,523,908 Devices and methods for facilitating controlled bone growth or repair 12 2012
8,906,093 Devices and methods for facilitating controlled bone growth or repair 0 2013
 
Cotera, Inc. (4)
8,597,362 Method and apparatus for force redistribution in articular joints 3 2010
9,278,004 Method and apparatus for altering biomechanics of the articular joints 0 2013
9,114,016 Method and apparatus for altering biomechanics of the articular joints 0 2014
8,845,724 Method and apparatus for altering biomechanics of the articular joints 3 2014
 
PROVIDENCE MEDICAL TECHNOLOGY, INC. (12)
9,011,492 Facet joint implants and delivery tools 1 2012
8,828,062 Vertebral joint implants and delivery tools 2 2012
8,753,377 Vertebral joint implants and delivery tools 2 2012
8,834,472 Vertebral joint implants and delivery tools 7 2012
8,753,345 Vertebral joint implants and delivery tools 0 2012
8,753,347 Vertebral joint implants and delivery tools 3 2012
8,623,054 Vertebral joint implants and delivery tools 5 2012
D745156 Spinal implant 0 2012
D732667 Cage spinal implant 3 2012
8,834,530 Cervical distraction method 3 2012
9,381,049 Composite spinal facet implant with textured surfaces 0 2013
9,333,086 Spinal facet cage implant 0 2013
 
DEPUY SYNTHES PRODUCTS, INC. (3)
* 9,089,372 Pedicular facet fusion screw with plate 0 2010
9,044,277 Pedicular facet fusion screw with plate 0 2010
* 2012/0010,662 PEDICULAR FACET FUSION SCREW WITH PLATE 14 2010
 
Pinnacle Spine Group, LLC (2)
9,380,932 Retractor devices for minimally invasive access to the spine 0 2012
9,216,096 Intervertebral implants and related tools 0 2015
* Cited By Examiner

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