Screening for the genetic defect causing tibial hemimelia in bovines
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United States of America Patent
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Apr 17, 2012
Grant Date -
Sep 24, 2009
app pub date -
Oct 16, 2006
filing date -
Oct 16, 2006
priority date (Note) -
Expired
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Abstract
The invention provides methods, materials and kits for analyzing DNA samples from bovine to determine whether the animal is a recessive carrier of a genetic mutation that is associated with tibial hemimelia. DNA-containing samples are analyzed by genetic testing to determine whether or not a deletion mutation is present in one of the alleles that encodes Aristaless-like4 (ALX4) protein, wherein the deletion mutation is associated with tibial hemimelia.
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