Fentanyl composition for nasal administration

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United States of America Patent

PATENT NO 8158651
APP PUB NO 20070134164A1
SERIAL NO

11656970

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Abstract

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The treatment of acute pain with a sufficient dosage by intranasal administration of fentanyl results in a time to onset of action comparable to intravenous administration and a significantly faster onset of action than nasal titration of fentanyl. The nasal administration of a sufficient amount of fentanyl to obtain pain relief has lower maximum plasma concentrations comparable to intravenous administration and results in lower rates of adverse events like respiratory depression, nausea and vomiting. Compositions fur use in the method are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
ISTITUTO GENTILI S R LVIA SAN GIUSEPPE COTTOLENGO 15 MILANO I-20143

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Grarup, Jesper Roskilde, DK 3 31
Nielsen, Hanne Wulf Svenborg, DK 3 31

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