Hydroxyalkyl substituted imidazoquinoline compounds and methods
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United States of America Patent
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Apr 17, 2012
Grant Date -
Mar 12, 2009
app pub date -
Feb 22, 2006
filing date -
Feb 23, 2005
priority date (Note) -
Expired
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Abstract
Certain imidazoquinolines with a hydroxymethyl or hydroxyethyl substituent at the 2-position, and an aryl or heteroaryl substituent at the 7-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for preferentially inducing IFN-α biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
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