Managing preload reserve by tracking the ventricular operating point with heart sounds
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United States of America Patent
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Apr 24, 2012
Grant Date -
Dec 17, 2009
app pub date -
Aug 25, 2009
filing date -
Jul 26, 2005
priority date (Note) -
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Abstract
A system and method for managing preload reserve and tracking the inotropic state of a patient's heart. The S1 heart sound is measured as a proxy for direct measurement of stroke volume. The S3 heart sound may be measured as a proxy for direct measurement of preload level. The S1-S3 pair yield a point on a Frank Starling type of curve, and reveal information regarding the patient's ventricular operating point and inotropic state. As an alternative, or in addition to, measurement of the S3 heart sound, the S4 heart sound may be measured or a direct pressure measurement may be made for the sake of determining the patient's preload level. The aforementioned measurements may be made by a cardiac rhythm management device, such as a pacemaker or implantable defibrillator.
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