Methods of diagnosing and treating migraine
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United States of America Patent
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Apr 24, 2012
Grant Date -
Dec 24, 2009
app pub date -
Apr 24, 2007
filing date -
Apr 25, 2006
priority date (Note) -
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Abstract
The present invention provides methods of diagnosing migraine attacks and determining predisposition of an individual to the development of migraine based on sodium level in the cerebrospinal fluid (CSF) and/or brain extracellular fluid. The invention also provides methods of treating migraine, wherein the individual is selected for treatment based in the individual's sodium level in the CSF and/or brain extracellular fluid. The CSF sodium level may be based on the sodium concentration in the saliva.
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