US Patent No: 8,163,533

Number of patents in Portfolio can not be more than 2000

Methods and compositions for combinatorial-based production of multivalent recombinant antigens

ALSO PUBLISHED AS: 20080318274

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Abstract

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The present invention provides methods and compositions for rapidly producing multivalent recombinant vaccines using filamentous fungal heterokaryons. The present invention relies on the use of filamentous fungal heterokaryons that are generated from combinations of two or more parent strains into which recombinant DNA molecules encoding variants of antigens derived from pathogenic organisms have been introduced. The resulting vaccines are multivalent.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
INTREXON CORPORATIONBLACKSBURG, VA72

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cambareri, Edward B Woodside, CA 4 0
Stuart, W Dorsey Kaneohe, HI 10 146

Cited Art Landscape

Patent Info (Count) # Cites Year
 
UNIVERSITY OF HAWAII (2)
5,643,745 Heterologous dimeric proteins produced in heterokaryons 25 1994
5,683,899 Methods and compositions for combinatorial-based discovery of new multimeric molecules 38 1996
 
IMMUNITOR COMPANY LTD. (1)
2003/0092,145 Viral vaccine composition, process, and methods of use 28 2001
 
INTREXON CORPORATION (1)
6,268,140 Combinatorial metabolic libraries 4 1999
 
NPS PHARMACEUTICALS, INC. (1)
4,885,249 Aspergillus niger transformation system 25 1984
 
ST. LOUIS UNIVERSITY, A NON-PROFIT ORG. (1)
4,486,533 Filamentous fungi functional replicating extrachromosomal element 29 1983
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (1)
4,816,405 Vectors for transformation by ascomycetes 23 1987
 
ZymoGenetics, Inc. (1)
4,935,349 Expression of higher eucaryotic genes in aspergillus 54 1987

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