PKC-activating compounds for the treatment of neurodegenerative diseases
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United States of America Patent
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Apr 24, 2012
Grant Date -
Jan 28, 2010
app pub date -
Jul 28, 2009
filing date -
Jul 28, 2008
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Abstract
The present invention relates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimer's disease and stroke using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids. The present invention also relates to methods of reducing neurodegeneration using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids.
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