Method for modulating insulin production
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United States of America Patent
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May 1, 2012
Grant Date -
May 28, 2009
app pub date -
Nov 7, 2008
filing date -
Nov 7, 2007
priority date (Note) -
Expired
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Abstract
The present invention provides screening methods for the detection of agents that affect various aspects of β-cell biology, particularly insulin gene expression. Screening methods are also provided for detection of agents that affect β-cell differentiation from progenitor cells. Additionally, agents identified using such methods are provided and are useful for increasing insulin gene expression and reducing lipotoxicity.
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