Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof
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United States of America Patent
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May 8, 2012
Grant Date -
Apr 17, 2003
app pub date -
Feb 28, 2002
filing date -
Apr 9, 1997
priority date (Note) -
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status (Latency Note)
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Abstract
The invention relates to methods of treating a subject having Alzheimer's Disease, comprising the step of administering an antibody molecule which is targeted to β amyloid peptide or to fragment thereof. In another embodiment the invention relates to methods of treating a disease or a disorder, characterized by amyloid beta deposition. In another embodiment, the invention relates to an antibody molecule, which is free end-specific for the N-terminus or the C-terminus of an amyloid β peptide and to a pharmaceutical composition thereof. In another embodiment, the invention relates to an antibody molecule, which is targeted to the free C or N-terminus of a N-and/or C-terminus truncated amyloid β peptide fragment.
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