Preparation for repairing cartilage tissue, especially articular cartilage defects
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United States of America Patent
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May 8, 2012
Grant Date -
Jun 28, 2007
app pub date -
Feb 23, 2004
filing date -
Feb 26, 2003
priority date (Note) -
In Force
status (Latency Note)
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Abstract
The invention relates to preparations which are suitable for repairing enchondral or osteochondral defects (4) by means of implantation, said preparations comprising a cartilage element (A) and optionally a bone element (B) which is connected to the cartilage element (A). The cartilage element (A) can already contain cells during the implantation or is populated after the implantation with cells migrating from surrounding tissue. The aim of the invention is to better equip the cartilage element (A) of one such preparation for integration into the surrounding tissue and/or for an easy-to-achieve, primary stability. To this end, said cartilage element is not homogeneously embodied but has different characteristics in a peripheral and/or basal region (2, 3) to those in a central region (3). Said differing characteristics (A) relate to the structure and/or composition of the matrix used and/or to the cells established in the matrix, and are in no way used to prevent the migration of cells into the preparation from the surrounding tissue.
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