US Patent No: 8,187,620

Number of patents in Portfolio can not be more than 2000

Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents

ALSO PUBLISHED AS: 20070224116

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates generally to a medical device, such as an intravascular stent, for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. More particularly, the invention pertains to a medical device having a metal oxide or metal material with a plurality of pores therein disposed on the surface of the medical device and a polymer disposed on the metal oxide or metal material. The invention also relates to medical devices having a surface and an outer region comprising a metal oxide or metal material having a plurality of pores therein and a polymer disposed on the metal oxide or metal material.

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First Claim

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all claims..

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BOSTON SCIENTIFIC SCIMED, INC.MAPLE GROVE, MN4950

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chandrasekaran, Chandru Mercer Island, WA 15 253
Radhakrishnan, Rajesh Brampton, CA 58 244

Cited Art Landscape

Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (231)
5,195,969 Co-extruded medical balloons and catheter using such balloons 290 1991
5,270,086 Multilayer extrusion of angioplasty balloons 390 1991
5,304,121 Drug delivery system making use of a hydrogel polymer coating 510 1991
5,366,504 Tubular medical prosthesis 447 1992
5,674,192 Drug delivery 214 1993
5,397,307 Drug delivery PTCA catheter and method for drug delivery 163 1993
5,449,382 Minimally invasive bioactivated endoprosthesis for vessel repair 377 1994
5,439,446 Stent and therapeutic delivery system 272 1994
6,017,577 Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices 94 1995
5,578,075 Minimally invasive bioactivated endoprosthesis for vessel repair 258 1995
5,824,077 Clad composite stent 138 1995
6,524,274 Triggered release hydrogel drug delivery system 107 1995
6,171,609 Therapeutic inhibitor of vascular smooth muscle cells 185 1995
5,772,864 Method for manufacturing implantable medical devices 160 1996
5,837,313 Drug release stent coating process 660 1996
6,120,536 Medical devices with long term non-thrombogenic coatings 562 1996
5,824,045 Vascular and endoluminal stents 213 1996
5,733,925 Therapeutic inhibitor of vascular smooth muscle cells 391 1996
6,306,144 Selective coating of a balloon catheter with lubricious material for stent deployment 87 1996
5,788,979 Biodegradable coating with inhibitory properties for application to biocompatible materials 360 1997
5,922,021 Intravascular stent 242 1997
5,879,697 Drug-releasing coatings for medical devices 197 1997
5,980,564 Bioabsorbable implantable endoprosthesis with reservoir 206 1997
6,174,330 Bioabsorbable marker having radiopaque constituents 279 1997
5,972,027 Porous stent drug delivery system 371 1997
6,290,721 Tubular medical endoprostheses 257 1997
6,099,562 Drug coating with topcoat 547 1997
6,358,556 Drug release stent coating 390 1998
5,980,566 Vascular and endoluminal stents with iridium oxide coating 114 1998
6,287,331 Tubular medical prosthesis 92 1998
2002/0032,477 DRUG RELEASE COATED STENT 94 1998
6,280,411 Localized delivery of drug agents 155 1998
6,652,581 Medical device with porous surface for controlled drug release and method of making the same 77 1998
6,099,561 Vascular and endoluminal stents with improved coatings 299 1998
6,159,142 Stent with radioactive coating for treating blood vessels to prevent restenosis 88 1998
6,419,692 Surface protection method for stents and balloon catheters for drug delivery 341 1999
6,245,104 Method of fabricating a biocompatible stent 102 1999
6,249,952 Method for manufacturing an expandable stent 101 1999
6,231,600 Stents with hybrid coating for medical devices 366 1999
6,217,607 Premounted stent delivery system for small vessels 55 1999
6,652,582 Bioabsorbable endoprosthesis having porosity for by-product collection 76 1999
6,253,443 Method of forming a stent 187 1999
6,440,503 Laser deposition of elements onto medical devices 46 2000
6,368,658 Coating medical devices using air suspension 255 2000
6,726,712 Prosthesis deployment device with translucent distal end 131 2000
6,284,305 Drug coating with topcoat 265 2000
6,387,121 Vascular and endoluminal stents with improved coatings 205 2000
6,478,815 Vascular and endoluminal stents 96 2000
6,491,666 Microfabricated devices for the delivery of molecules into a carrier fluid 216 2000
6,517,888 Method for manufacturing a medical device having a coated portion by laser ablation 160 2000
6,545,097 Drug delivery compositions and medical devices containing block copolymer 232 2000
6,398,806 Monolayer modification to gold coated stents to reduce adsorption of protein 55 2000
6,752,829 Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same 95 2001
6,767,360 Vascular stent with composite structure for magnetic reasonance imaging capabilities 71 2001
6,607,598 Device for protecting medical devices during a coating process 72 2001
6,783,543 Intravascular stent with increasing coating retaining capacity 121 2001
2001/0029,660 Stent drug delivery system 75 2001
6,939,320 Localized delivery of drug agents 86 2001
6,676,987 Coating a medical appliance with a bubble jet printing head 108 2001
6,620,194 Drug coating with topcoat 65 2001
6,669,980 Method for spray-coating medical devices 175 2001
6,764,709 Method for making and measuring a coating on the surface of a medical device using an ultraviolet laser 55 2001
6,807,440 Ceramic reinforcement members for MRI devices 44 2001
7,014,654 Stent designed for the delivery of therapeutic substance or other agents 42 2001
2003/0153,971 Metal reinforced biodegradable intraluminal stents 69 2002
2002/0144,757 Stainless steel alloy with improved radiopaque characteristics 60 2002
2003/0018,380 Platinum enhanced alloy and intravascular or implantable medical devices manufactured therefrom 77 2002
2003/0077,200 Enhanced radiopaque alloy stent 69 2002
2003/0236,514 Implantable or insertable medical devices for controlled delivery of a therapeutic agent 74 2002
2004/0022,824 Controlled drug delivery 28 2002
7,101,391 Primarily niobium stent 49 2002
6,908,622 Optimized dosing for drug coated stents 68 2002
7,060,051 Multi-balloon catheter with hydrogel coating 74 2002
2004/0059,409 Method of applying coatings to a medical device 71 2002
6,971,813 Contact coating of prostheses 71 2002
2004/0098,089 Medical devices 51 2002
2004/0106,987 Medical devices for delivery of therapeutic agents 77 2002
6,803,070 Apparatus and method for embedding nanoparticles in polymeric medical devices 48 2002
2004/0143,317 Medical devices 156 2003
7,402,173 Metal stent with surface layer of noble metal oxide and method of fabrication 46 2003
2004/0106,985 Intravascular stent 90 2003
2004/0093,071 Intravascular stent with increasing coating retaining capacity 52 2003
7,482,034 Expandable mask stent coating method 30 2003
7,101,394 Energetically-controlled delivery of biologically active material from an implanted medical device 50 2003
2004/0230,290 Medical devices and methods of making the same 57 2003
2004/0234,748 Electrostatic coating of a device 45 2003
7,011,680 Stent device and method 57 2003
2004/0225,347 Intravascular stent with increasing coating retaining capacity 24 2003
7,052,488 Implantable drug delivery device 77 2003
2005/0037,047 Medical devices comprising spray dried microparticles 89 2003
7,713,297 Drug-releasing stent with ceramic-containing layer 43 2003
2004/0039,438 Vascular and endoluminal stents with multi-layer coating including porous radiopaque layer 70 2003
2005/0060,021 Medical devices 58 2003
2005/0060,020 Covered stent with biologically active material 133 2003
2005/0070,990 Medical devices and methods of making same 59 2003
2004/0067,301 Medical device with porous surface for controlled drug release and method of making the same 47 2003
2005/0074,479 Using bucky paper as a therapeutic aid in medical applications 45 2003
2005/0087,520 Method and apparatus for selective ablation of coatings from medical devices 43 2003
7,435,256 Method and apparatus for controlled delivery of active substance 23 2003
2004/0181,276 Longitudinally flexible expandable stent 45 2003
2005/0131,522 Medical devices and methods of making the same 93 2003
2005/0149,102 Medical device systems 34 2003
2005/0159,805 Functional coatings and designs for medical implants 47 2004
2005/0163,954 Medical devices 57 2004
7,041,130 Stent for controlled release of drug 81 2004
2005/0129,727 Localized drug delivery using drug-loaded nanocapsules 63 2004
2005/0182,478 Laser shock peening of medical devices 44 2004
2005/0192,657 Medical devices 58 2004
2005/0196,518 Method and system for making a coated medical device 36 2004
2005/0015,142 Coated medical device and method for manufacturing the same 49 2004
2005/0203,606 Stent system for preventing restenosis 40 2004
2005/0208,100 Medical articles having regions with polyelectrolyte multilayer coatings for regulating drug release 81 2004
6,861,088 Method for spray-coating a medical device having a tubular wall such as a stent 142 2004
2005/0220,853 Controlled delivery of therapeutic agents from medical articles 51 2004
2004/0247,671 Solid drug formulation and device for storage and controlled delivery thereof 67 2004
2005/0266,039 Coated medical device and method for making the same 45 2004
2005/0266,040 Medical devices composed of porous metallic materials for delivering biologically active materials 48 2004
2006/0025,848 Medical device having a coating layer with structural elements therein and method of making the same 57 2004
2006/0034,884 Coated medical device having an increased coating surface area 31 2004
2006/0052,744 Method of coating a medical device using an electrowetting process, system for using the method, and device made by the method 54 2004
2006/0079,863 Medical devices coated with diamond-like carbon 31 2004
2005/0110,214 Composite stent with inner and outer stent elements and method of using the same 32 2004
2006/0088,566 Method of controlling drug release from a coated medical device through the use of nucleating agents 49 2004
2006/0088,567 Method of manufacturing a medical device having a porous coating thereon 45 2004
2006/0093,643 Medical device for delivering therapeutic agents over different time periods 46 2004
2006/0095,123 Stent for delivering a therapeutic agent having increased body tissue contact surface 27 2004
2006/0100,696 Medical devices and methods of making the same 49 2004
2006/0122,694 Medical devices and methods of making the same 51 2004
2006/0127,443 Medical devices having vapor deposited nanoporous coatings for controlled therapeutic agent delivery 65 2004
2006/0129,215 Medical devices having nanostructured regions for controlled tissue biocompatibility and drug delivery 64 2004
2006/0125,144 Stent and stent manufacturing methods 24 2004
2005/0197,687 Medical devices including metallic films and methods for making same 47 2004
2005/0197,689 Medical devices including metallic films and methods for making same 28 2004
2006/0153,729 Medical devices and methods of making the same 55 2005
2006/0171,985 Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility 37 2005
2006/0230,476 Polymeric/ceramic composite materials for use in medical devices 64 2005
2006/0222,844 Medical devices including composites 48 2005
2006/0233,941 Method of coating a medical device utilizing an ion-based thin film deposition technique, a system for coating a medical device, and a medical device produced by the method 48 2005
2005/0261,760 Medical devices and methods of making the same 73 2005
2006/0276,910 Endoprostheses 26 2005
2007/0038,176 Medical devices with machined layers for controlled communications with underlying regions 47 2005
7,914,809 Lubricious composites for medical devices 12 2005
2007/0048,452 Apparatus and method for field-injection electrostatic spray coating of medical devices 30 2005
2007/0072,978 Organic-inorganic hybrid particle material and polymer compositions containing same 25 2005
2006/0038,027 Apparatus and method for fine bore orifice spray coating of medical devices and pre-filming atomization 57 2005
2007/0110,888 Coated and imprinted medical devices and methods of making the same 33 2005
2007/0112,421 Medical device with a grooved surface 33 2005
2007/0134,288 Anti-adhesion agents for drug coatings 48 2005
2007/0154,513 Medical devices having multiple charged layers 28 2005
2007/0156,231 Bioerodible endoprostheses and methods of making the same 51 2006
2007/0190,104 Coating comprising an adhesive polymeric material for a medical device and method of preparing the same 46 2006
2007/0191,923 Medical balloons and methods of making the same 47 2006
2007/0191,931 Bioerodible endoprostheses and methods of making the same 48 2006
2007/0212,547 Method of powder coating medical devices 32 2006
2007/0224,244 Corrosion resistant coatings for biodegradable metallic implants 52 2006
2007/0224,235 Medical devices having nanoporous coatings for controlled therapeutic agent delivery 35 2006
2007/0224,116 Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents 45 2006
2007/0244,569 Endoprosthesis having a fiber meshwork disposed thereon 49 2006
2007/0254,091 System and method for electrostatic-assisted spray coating of a medical device 27 2006
2007/0264,303 Coating for medical devices comprising an inorganic or ceramic oxide and a therapeutic agent 46 2006
2007/0269,480 Medical devices having bioactive surfaces 25 2006
2008/0003,251 Coatings for medical devices comprising a therapeutic agent and a metallic material 49 2006
2008/0008,654 Medical devices having a temporary radiopaque coating 55 2006
2008/0058,921 IMPROVED ADHESION OF A POLYMERIC COATING OF A DRUG ELUTING STENT 44 2006
2008/0188,836 Medical devices having nanoporous coatings for controlled therapeutic agent delivery 34 2007
2008/0249,615 STENTS WITH CERAMIC DRUG RESERVOIR LAYER AND METHODS OF MAKING AND USING THE SAME 42 2007
2008/0249,600 STENTS WITH DRUG RESERVOIR LAYER AND METHODS OF MAKING AND USING THE SAME 44 2007
2008/0051,881 Medical devices comprising porous layers for the release of therapeutic agents 53 2007
2008/0275,543 Stent 25 2007
2008/0294,236 Endoprosthesis with Select Ceramic and Polymer Coatings 45 2007
2008/0294,246 Endoprosthesis with Select Ceramic Morphology 46 2007
2008/0050,415 Polymeric/ceramic composite materials for use in medical devices 31 2007
2008/0004,691 MEDICAL DEVICES WITH SELECTIVE COATING 45 2007
2009/0018,639 ENDOPROSTHESIS COATING 42 2007
2009/0018,647 ENDOPROSTHESIS COATING 43 2007
2009/0018,644 Boron-Enhanced Shape Memory Endoprostheses 27 2007
2008/0160,259 MEDICAL DEVICES AND METHODS OF MAKING THE SAME 48 2007
2009/0030,504 Medical devices comprising porous inorganic fibers for the release of therapeutic agents 47 2007
2009/0138,077 Articles having ceramic coated surfaces 34 2007
2007/0299,509 MEDICAL DEVICE WITH POROUS SURFACE FOR CONTROLLED DRUG RELEASE AND METHOD OF MAKING THE SAME 42 2007
2008/0071,355 Medical Devices with Drug-Eluting Coating 57 2007
2008/0071,348 Medical Devices 42 2007
2008/0071,349 Medical Devices 47 2007
2008/0071,350 ENDOPROSTHESES 48 2007
2008/0071,358 ENDOPROSTHESES 48 2007
2009/0076,588 Endoprosthesis 46 2007
2008/0071,351 ENDOPROSTHESIS WITH ADJUSTABLE SURFACE FEATURES 45 2007
2008/0071,352 BIOERODIBLE ENDOPROSTHESIS WITH BIOSTABLE INORGANIC LAYERS 45 2007
2008/0071,353 ENDOPROSTHESIS CONTAINING MAGNETIC INDUCTION PARTICLES 44 2007
2008/0086,201 MAGNETIZED BIOERODIBLE ENDOPROSTHESIS 44 2007
2009/0076,595 Medical devices having bioerodable layers for the release of therapeutic agents 34 2007
2008/0097,577 MEDICAL DEVICE HYDROGEN SURFACE TREATMENT BY ELECTROCHEMICAL REDUCTION 46 2007
2008/0147,177 ENDOPROSTHESIS WITH COATINGS 51 2007
2008/0145,400 Ion Bombardment of Medical Devices 43 2007
2009/0118,809 ENDOPROSTHESIS WITH POROUS RESERVOIR AND NON-POLYMER DIFFUSION LAYER 43 2007
2009/0118,812 ENDOPROSTHESIS COATING 43 2007
2009/0118,813 NANO-PATTERNED IMPLANT SURFACES 42 2007
2009/0118,814 ENDOPROSTHESIS COATING 42 2007
2009/0118,815 STENT 43 2007
2009/0118,818 ENDOPROSTHESIS WITH COATING 42 2007
2009/0118,820 DEFORMABLE UNDERLAYER FOR STENT 42 2007
2009/0118,821 ENDOPROSTHESIS WITH POROUS RESERVOIR AND NON-POLYMER DIFFUSION LAYER 44 2007
2009/0118,822 STENT WITH EMBEDDED MATERIAL 44 2007
2009/0118,823 ENDOPROSTHESIS WITH POROUS RESERVOIR 45 2007
2009/0123,521 Medical devices having coatings for controlled therapeutic agent delivery 49 2007
7,749,264 Medical devices and methods of making the same 43 2008
2008/0241,218 Coated medical devices for abluminal drug delivery 43 2008
2008/0243,231 Medical device with a porous surface for delivery of a therapeutic agent 51 2008
2009/0018,642 Methods to improve the stability of celluar adhesive proteins and peptides 23 2008
2008/0255,657 STENT WITH UNCONNECTED STENT SEGMENTS 23 2008
2009/0123,517 MEDICAL DEVICES FOR RELEASING THERAPEUTIC AGENT AND METHODS OF MAKING THE SAME 43 2008
2009/0281,613 Endoprostheses 43 2008
2009/0287,301 Coating for medical implants 43 2008
2009/0306,765 Bioerodible Endoprosthesis 43 2008
2009/0012,603 IMPLANTABLE MEDICAL DEVICES HAVING ADJUSTABLE PORE VOLUME AND METHODS FOR MAKING THE SAME 24 2008
2009/0149,942 ENDOPROSTHESIS HAVING A NON-FOULING SURFACE 43 2008
2009/0028,785 MEDICAL DEVICES WITH COATINGS FOR DELIVERY OF A THERAPEUTIC AGENT 43 2008
2009/0157,172 STENTS WITH POLYMER-FREE COATINGS FOR DELIVERING A THERAPEUTIC AGENT 49 2008
2010/0030,326 Bioerodible Endoprosthesis 42 2008
2009/0157,165 Degradable Endoprosthesis 43 2008
2009/0157,166 Medical Devices Having Porous Component For Controlled Diffusion 26 2008
2010/0008,970 Drug-Eluting Endoprosthesis 45 2008
2009/0192,593 Stent for Delivery a Therapeutic Agent from a Side Surface of a Stent StSrut 35 2009
2009/0202,610 Medical Implants With Polysaccharide Drug Eluting Coatings 43 2009
2009/0259,300 Medical Devices With an Interlocking Coating and Methods of Making the Same 42 2009
2009/0264,975 MEDICAL DEVICES HAVING A COATING OF INORGANIC MATERIAL 27 2009
2009/0319,032 ENDOPROSTHESIS COATING 16 2009
2010/0028,403 MEDICAL DEVICES FOR THERAPEUTIC AGENT DELIVERY 15 2009
2010/0057,197 MEDICAL DEVICES HAVING INORGANIC COATINGS FOR THERAPEUTIC AGENT DELIVERY 47 2009
2010/0070,022 LAYER BY LAYER MANUFACTURING OF A STENT 33 2009
7,922,756 Stent 15 2010
 
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5,649,977 Metal reinforced polymer stent 477 1994
5,605,696 Drug loaded polymeric material and method of manufacture 619 1995
6,174,329 Protective coating for a stent with intermediate radiopaque coating 192 1996
5,780,807 Method and apparatus for direct laser cutting of metal stents 342 1997
5,843,172 Porous medicated stent 377 1997
6,240,616 Method of manufacturing a medicated porous metal prosthesis 437 1997
6,287,628 Porous prosthesis and a method of depositing substances into the pores 338 1999
6,251,136 Method of layering a three-coated stent using pharmacological and polymeric agents 327 1999
6,471,721 Vascular stent having increased radiopacity and method for making same 114 1999
6,527,801 Biodegradable drug delivery material for stent 301 2000
6,395,326 Apparatus and method for depositing a coating onto a surface of a prosthesis 460 2000
6,585,765 Implantable device having substances impregnated therein and a method of impregnating the same 259 2000
6,254,632 Implantable medical device having protruding surface structures for drug delivery and cover attachment 463 2000
6,716,444 Barriers for polymer-coated implantable medical devices and methods for making the same 262 2000
6,805,898 Surface features of an implantable medical device 171 2000
6,506,437 Methods of coating an implantable device having depots formed in a surface thereof 345 2000
6,558,733 Method for etching a micropatterned microdepot prosthesis 295 2000
6,663,664 Self-expanding stent with time variable radial force 96 2000
6,758,859 Increased drug-loading and reduced stress drug delivery device 242 2000
6,913,617 Method for creating a textured surface on an implantable medical device 62 2000
6,663,662 Diffusion barrier layer for implantable devices 265 2000
6,790,228 Coating for implantable devices and a method of forming the same 216 2000
2001/0014,717 Coating for implantable devices and a method of forming the same 188 2000
2002/0123,801 Diffusion barrier layer for implantable devices 178 2000
6,635,082 Radiopaque stent 82 2000
6,641,607 Double tube stent 80 2000
2002/0087,123 Adhesion of heparin-containing coatings to blood-contacting surfaces of medical devices 178 2001
6,544,582 Method and apparatus for coating an implantable device 245 2001
6,780,424 Controlled morphologies in polymer drug for release of drugs from polymer films 110 2001
6,673,105 Metal prosthesis coated with expandable ePTFE 73 2001
6,764,505 Variable surface area stent 291 2001
6,712,845 Coating for a stent and a method of forming the same 269 2001
2002/0155,212 Coating for a stent and a method of forming the same 228 2001
6,660,034 Stent for increasing blood flow to ischemic tissues and a method of using the same 256 2001
6,656,506 Microparticle coated medical device 190 2001
2002/0183,581 Radiation or drug delivery source with activity gradient to minimize edge effects 198 2001
6,712,844 MRI compatible stent 72 2001
2003/0004,563 Polymeric stent suitable for imaging by MRI and fluoroscopy 95 2001
6,979,346 System and method for improved stent retention 63 2001
6,753,071 Rate-reducing membrane for release of an agent 263 2001
2003/0104,028 Rate limiting barriers for implantable devices and methods for fabrication thereof 56 2001
6,866,805 Hybrid intravascular stent 89 2001
6,616,765 Apparatus and method for depositing a coating onto a surface of a prosthesis 221 2002
6,723,120 Medicated porous metal prosthesis 206 2002
2004/0088,038 Porous metal for drug-loaded stents 80 2002
7,169,178 Stent with drug coating 68 2002
6,908,624 Coating for implantable devices and a method of forming the same 109 2002
6,725,901 Methods of manufacture of fully consolidated or porous medical devices 62 2002
6,896,697 Intravascular stent 72 2002
7,105,018 Drug-eluting stent cover and method of use 68 2002
7,163,715 Spray processing of porous medical devices 87 2002
2004/0224,001 Stent coatings comprising hydrophilic additives 102 2003
6,846,323 Intravascular stent 166 2003
2004/0230,293 INTRAVASCULAR STENT 83 2003
2005/0021,127 Porous glass fused onto stent for drug retention 56 2003
7,056,591 Hydrophobic biologically absorbable coatings for drug delivery devices and methods for fabricating the same 57 2003
7,247,166 Intravascular stent with extendible end rings 25 2003
7,198,675 Stent mandrel fixture and method for selectively coating surfaces of a stent 62 2003
2005/0069,630 Stent mandrel fixture and method for selectively coating surfaces of a stent 75 2003
6,953,560 Barriers for polymer-coated implantable medical devices and methods for making the same 65 2003
7,563,324 System and method for coating an implantable medical device 35 2003
2004/0234,737 Rate-reducing membrane for release of an agent 49 2004
7,229,471 Compositions containing fast-leaching plasticizers for improved performance of medical devices 74 2004
2006/0136,048 Abluminal, multilayer coating constructs for drug-delivery stents 63 2004
7,638,156 Apparatus and method for selectively coating a medical article 25 2005
2007/0148,251 Nanoparticle releasing medical devices 55 2005
2007/0003,589 Coatings for implantable medical devices containing attractants for endothelial cells 57 2006
7,416,558 Drug-eluting stent cover and method of use 43 2006
2007/0032,858 Stent with drug coating 46 2006
2007/0036,905 Method and apparatus for spray processing of porous medical devices 47 2006
2007/0055,349 Stent with drug coating 44 2006
2007/0055,354 Stent with drug coating 42 2006
2007/0059,435 Stent with drug coating 42 2006
 
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5,163,958 Carbon coated tubular endoprosthesis 404 1991
5,891,108 Drug delivery stent 207 1994
5,882,335 Retrievable drug delivery stent 150 1996
6,273,913 Modified stent useful for delivery of drugs along stent strut 585 1998
5,902,266 Method for delivering a liquid solution to the interior wall surface of a vessel 131 1998
2001/0014,821 BALLOON CATHETER AND STENT DELIVERY SYSTEM HAVING ENHANCED STENT RETENTION 48 1998
6,325,825 Stent with variable wall thickness 145 1999
6,315,708 Stent with self-expanding end sections 86 2000
2002/0051,730 Coated medical devices and sterilization thereof 273 2001
6,776,022 Stent with variable wall thickness 54 2001
6,852,122 Coated endovascular AAA device 78 2003
2005/0137,677 Endovascular graft with differentiable porosity along its length 75 2003
2004/0236,416 Increased biocompatibility of implantable medical devices 59 2004
2006/0200,229 Geometry and material for use in high strength, high flexibility, controlled recoil drug eluting stents 46 2005
2008/0086,199 BIOABSORBABLE DEVICE HAVING COMPOSITE STRUCTURE FOR ACCELERATING DEGRADATION 59 2006
2008/0152,929 POLYMER COATING FOR MEDICAL DEVICES 42 2006
2010/0131,050 ABSORBABLE STENT HAVING A COATING FOR CONTROLLING DEGRADATION OF THE STENT AND MAINTAINING pH NEUTRALITY 41 2008
 
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6,918,929 Drug-polymer coated stent with pegylated styrenic block copolymers 39 2003
7,001,421 Stent with phenoxy primer coating 53 2003
6,979,348 Reflowed drug-polymer coated stent and method thereof 70 2003
2005/0070,996 Drug-eluting stent for controlled drug delivery 73 2003
2006/0149,365 Stent with eccentric coating 36 2003
2004/0111,150 Medical device for delivering a therapeutic substance and method therefor 42 2003
2004/0236,415 Medical devices having drug releasing polymer reservoirs 52 2003
2005/0180,919 Stent with radiopaque and encapsulant coatings 53 2004
2004/0230,176 System for treating a vascular condition that inhibits restenosis at stent ends 71 2004
2004/0236,399 Stent with improved surface adhesion 33 2004
2005/0021,128 Compliant, porous, rolled stent 46 2004
2005/0267,561 System and method for stent deployment and infusion of a therapeutic agent into tissue adjacent to the stent ends 42 2004
7,575,632 Reflowed drug-polymer coated stent and method thereof 12 2007
7,575,593 Implantable device with reservoirs for increased drug loading 33 2007
2008/0243,240 Biodegradable Metal Barrier Layer for a Drug-Eluting Stent 43 2007
 
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5,500,013 Biodegradable drug delivery vascular stent 333 1995
5,769,883 Biodegradable drug delivery vascular stent 306 1995
6,387,124 Biodegradable drug delivery vascular stent 109 1999
6,395,325 Porous membranes 70 2000
2002/0138,136 Medical device having radio-opacification and barrier layers 74 2001
2002/0065,553 Method for manufacturing a medical device having a coated portion by laser ablation 136 2001
6,652,575 Stent with smooth ends 111 2001
6,869,443 Biodegradable drug delivery vascular stent 131 2002
2004/0086,674 Laser sintering process and devices made therefrom 37 2002
2004/0098,119 Stent with smooth ends 47 2003
2006/0127,442 Use of supercritical fluids to incorporate biologically active agents into nanoporous medical articles 30 2004
2005/0278,016 Stent designed for the delivery of therapeutic substance or other agents 58 2005
2006/0264,138 Composite ePTFE/textile prosthesis 47 2006
 
UNIVERSITY OF VIRGINIA (15)
7,294,409 Medical devices having porous layers and methods for making same 46 2003
2005/0070,989 Medical devices having porous layers and methods for making the same 60 2004
2006/0121,080 Medical devices having nanoporous layers and methods for making the same 80 2005
2006/0193,886 Medical devices with nanoporous layers and topcoats 56 2006
2006/0193,887 Medical devices having nanoporous bonding layers 50 2006
2006/0193,888 Methods for using medical devices having nanoporous layers 51 2006
2006/0193,889 Nanoporous layers using thermal dealloying 48 2006
2006/0193,890 Method for loading nanoporous layers with therapeutic agent 61 2006
2006/0276,877 Dealloyed nanoporous stents 55 2006
2006/0276,878 Dealloyed nanoporous stents 50 2006
2006/0276,884 Nanoporous stents with magnesium leaching 49 2006
2006/0276,885 Nanoporous stents with improved radiolucency 49 2006
2006/0271,169 Stent with nanoporous surface 48 2006
2006/0276,879 Medical devices having porous layers and methods for making the same 47 2006
2008/0086,198 NANOPOROUS STENTS WITH ENHANCED CELLULAR ADHESION AND REDUCED NEOINTIMAL FORMATION 21 2007
 
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4,886,062 Intravascular radially expandable stent and method of implant 1303 1987
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5,776,184 Intravasoular stent and method 380 1996
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2004/0220,510 Occlusion resistant hydrocephalic shunt 55 2004
2005/0079,199 Porous coatings for drug release from medical devices 62 2004
 
MEDLOGICS DEVICE CORPORATION (12)
2003/0060,873 Metallic structures incorporating bioactive materials and methods for creating the same 76 2002
7,208,172 Metallic composite coating for delivery of therapeutic agents from the surface of implantable devices 43 2003
2005/0119,723 Medical device with porous surface containing bioerodable bioactive composites and related methods 65 2003
2005/0106,212 Metallic structures incorporating bioactive materials and methods for creating the same 51 2004
2005/0186,250 Metallic structures incorporating bioactive materials and methods for creating the same 42 2005
2006/0062,820 Metallic structures incorporating bioactive materials and methods for creating the same 48 2005
2006/0051,397 Metallic structures incorporating bioactive materials and methods for creating the same 43 2005
2006/0085,062 Implantable stent with endothelialization factor 44 2005
2006/0115,512 Metallic structures incorporating bioactive materials and methods for creating the same 46 2005
2007/0073,390 Methods and devices for enhanced adhesion between metallic substrates and bioactive material-containing coatings 42 2005
2007/0071,789 Bioactive Material Delivery Systems Comprising Sol-Gel Compositions 24 2006
2007/0181,433 METALLIC COMPOSITE COATINGS FOR DELIVERY OF THERAPEUTIC AGENTS FROM THE SURFACE OF IMPLANTABLE DEVICES 42 2007
 
ADVANCED BIO PROSTHETIC SURFACES, LTD. (11)
6,190,404 Intravascular stent and method for manufacturing an intravascular stent 114 1998
6,379,383 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 203 1999
6,537,310 Endoluminal implantable devices and method of making same 139 2000
6,820,676 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 76 2000
6,849,085 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and method of making same 118 2001
6,695,865 Embolic protection device 142 2002
6,733,513 Balloon catheter having metal balloon and method of making same 96 2002
6,936,066 Complaint implantable medical devices and methods of making same 119 2002
6,923,829 Implantable expandable medical devices having regions of differential mechanical properties and methods of making same 42 2002
2004/0181,252 Balloon catheter having metal balloon and method of making same 60 2003
7,235,098 Medical devices having MEMs functionality and methods of making same 46 2004
 
ADVANCED BIO PROSTHETIC SURFACES, LTD. (11)
2001/0001,834 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 58 2000
2001/0032,013 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and method of making same 165 2001
2002/0165,600 Guidewires and thin film catheter-sheaths and method of making same 63 2002
2003/0059,640 High strength vacuum deposited nitinol alloy films and method of making same 104 2002
2003/0074,053 Endoluminal implantable stent-grafts 49 2002
2003/0130,718 Endoluminal implantable stent-grafts 60 2002
2005/0072,544 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 42 2004
2005/0131,521 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and methods of making same 42 2005
2005/0165,468 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and methods of making same 49 2005
2005/0232,968 Implantable materials having engineered surfaces and method of making same 44 2005
2006/0015,175 Compliant implantable medical devices and methods of making same 42 2005
 
INNOVATIONAL HOLDINGS LLC (11)
6,241,762 Expandable medical device with ductile hinges 240 1998
2003/0009,214 Medical device with beneficial agent delivery mechanism 79 2002
7,056,338 Therapeutic agent delivery device with controlled therapeutic agent release rates 78 2003
2004/0142,014 Method and apparatus for reducing tissue damage after ischemic injury 65 2003
2004/0143,321 Expandable medical device and method for treating chronic total occlusions with local delivery of an angiogenic factor 68 2003
2004/0202,692 Implantable medical device and method for in situ selective modulation of agent delivery 67 2004
2005/0100,577 Expandable medical device with beneficial agent matrix formed by a multi solvent system 54 2004
2004/0254,635 Expandable medical device for delivery of beneficial agent 58 2004
7,758,636 Expandable medical device with openings for delivery of multiple beneficial agents 23 2005
2006/0222,679 System and method for loading a beneficial agent into a medical device 44 2006
2006/0229,713 Implantable medical device with openings for delivery of beneficial agents with combination release kinetics 46 2006
 
LIFESHIELD SCIENCES LLC (10)
4,657,544 Cardiovascular graft and method of forming same 101 1984
5,693,085 Stent with collagen 495 1995
5,758,562 Process for manufacturing braided composite prosthesis 105 1996
5,741,331 Biostable elastomeric polymers having quaternary carbons 131 1996
6,391,052 Stent with collagen 163 1997
5,968,091 Stents and stent grafts having enhanced hoop strength and methods of making the same 240 1997
6,139,573 Conformal laminate stent device 142 1998
6,514,283 Intraluminal lining 128 2001
6,827,737 EPTFE covering for endovascular prostheses and method of manufacture 64 2001
2004/0158,312 Braided endoluminal device having tapered filaments 5 2003
 
WYETH (10)
7,261,735 Local drug delivery devices and methods for maintaining the drug coatings thereon 56 2001
7,195,640 Coated medical devices for the treatment of vulnerable plaque 67 2002
2004/0002,755 Method and apparatus for treating vulnerable coronary plaques using drug-eluting stents 30 2002
2003/0204,168 Coated vascular devices 141 2002
2004/0167,572 Coated medical devices 319 2003
2005/0136,090 Local vascular delivery of trichostatin a alone or in combination with sirolimus to prevent restenosis following vascular injury 71 2003
2005/0004,663 Heparin barrier coating for controlled drug release 87 2004
2005/0033,417 Coating for controlled release of a therapeutic agent 68 2004
2006/0129,225 Device for the delivery of a cardioprotective agent to ischemic reperfused myocardium 64 2004
2007/0135,908 Absorbable stent comprising coating for controlling degradation and maintaining pH neutrality 48 2005
 
BIOPHAN TECHNOLOGIES, INC. (9)
6,506,972 Magnetically shielded conductor 97 2002
6,673,999 Magnetically shielded assembly 91 2002
6,713,671 Magnetically shielded assembly 96 2002
6,765,144 Magnetic resonance imaging coated assembly 103 2003
6,815,609 Nanomagnetic composition 65 2003
2005/0107,870 Medical device with multiple coating layers 148 2004
2005/0216,075 Materials and devices of enhanced electromagnetic transparency 69 2005
2006/0142,853 Coated substrate assembly 30 2005
2006/0140,867 Coated stent assembly and coating materials 22 2005
 
CID S.P.A. (8)
6,638,302 Stent for angioplasty and associated production process 96 1997
6,565,602 Angioplasty stents 79 2001
6,699,281 Angioplasty stents 116 2002
2003/0195,613 Stent for angioplasty and associated production process 59 2003
7,344,563 Angioplasty stents 53 2004
2005/0209,681 Stent for endoluminal delivery of active principles or agents 48 2005
2007/0151,093 STENT FOR ANGIOPLASTY AND ASSOCIATED PRODUCTION PROCESS 43 2007
2008/0140,186 PROCESS FOR PRODUCING STENTS AND CORRESPONDING STENTS 50 2008
 
MED INSTITUTE, INC. (8)
5,609,629 Coated implantable medical device 669 1995
6,096,070 Coated implantable medical device 798 1996
5,824,049 Coated implantable medical device 764 1996
5,873,904 Silver implantable medical device 765 1997
6,530,951 Silver implantable medical device 321 1997
6,299,604 Coated implantable medical device 624 1999
6,918,927 Coated implantable medical device 159 2001
2007/0073,385 Eluting, implantable medical device 67 2006
 
AVANTEC VASCULAR CORPORATION (6)
6,471,980 Intravascular delivery of mycophenolic acid 149 2001
7,077,859 Apparatus and methods for variably controlled substance delivery from implanted prostheses 96 2001
7,083,642 Delivery of therapeutic capable agents 59 2002
2003/0033,007 Methods and devices for delivery of therapeutic capable agents with variable release profile 75 2002
2005/0107,869 Apparatus and methods for controlled substance delivery from implanted prostheses 36 2004
2006/0212,109 Delivery of therapeutic capable agents 33 2006
 
ABBOTT CARDIOVASCULAR SYSTEMS INC. (5)
2003/0083,731 Manufacture of fine-grained material for use in medical devices 55 2001
7,691,461 Hybrid stent and method of making 33 2002
8,029,816 Medical device coated with a coating containing elastin pentapeptide VGVPG 13 2007
2008/0306,584 Implantable medical devices for local and regional treatment 44 2007
7,901,452 Method to fabricate a stent having selected morphology to reduce restenosis 14 2007
 
BOSTON SCIENTIFIC CORPORATION (5)
5,954,706 Drug delivery 137 1995
5,843,089 Stent lining 159 1996
5,928,247 Stent placement device with medication dispenser and method 51 1997
6,364,856 Medical device with sponge coating for controlled drug release 158 1998
5,968,092 Method for making a biodegradable stent 155 1998
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (5)
5,888,591 Chemical vapor deposition of fluorocarbon polymer thin films 77 1996
5,797,898 Microchip drug delivery devices 337 1996
6,013,591 Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production 160 1998
6,045,877 Pyrolytic chemical vapor deposition of silicone films 112 1998
6,156,435 Chemical vapor deposition of fluorocarbon polymer thin films 47 1999
 
SORIN BIOMEDICA CARDIO S.R.L. (5)
2004/0167,612 Process for producing stents and corresponding stents 46 2004
2007/0065,418 Method and device for cellular therapy 44 2006
2007/0219,626 Stents made of biodegradable and non-biodegradable materials 46 2007
2007/0191,928 Angioplasty stents 43 2007
2008/0288,048 STENTS FOR ANGIOPLASTY 42 2007
 
ABPS VENTURE ONE, LTD. (4)
6,458,153 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 378 1999
6,652,578 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 257 2001
2003/0023,300 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 172 2002
2006/0167,543 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 128 2006
 
BIOSENSORS INTERNATIONAL GROUP, LTD. (4)
2003/0225,450 Drug-delivery endovascular stent and method for treating restenosis 40 2003
7,727,275 Drug-delivery endovascular stent and method of forming the same 24 2004
2006/0069,427 Drug-delivery endovascular stent and method for treating restenosis 49 2005
2007/0173,923 Drug reservoir stent 69 2006
 
Biotronik Mess-und Therapiegeraete GmbH & Co. (4)
6,805,709 Stent having discontinuous coating in the form of coating islands 73 2000
6,899,914 Method of applying a marker element to an implant and an implant provided with a marker element 43 2001
6,849,089 Implant with proliferation-inhibiting substance 72 2002
2005/0027,350 Endovascular implant for the injection of an active substance into the media of a blood vessel 45 2003
 
CARDIAC PACEMAKERS, INC. (4)
6,212,434 Single pass lead system 101 1998
6,361,780 Microporous drug delivery system 57 1998
2005/0131,509 Coatings for implantable electrodes 58 2003
2006/0035,026 Coatings for implantable electrodes 47 2005
 
ISOTECHNIKA INC. (4)
6,342,507 Deuterated rapamycin compounds, method and uses thereof 46 1999
6,503,921 Deuterated rapamycin compounds, methods and uses thereof 52 2001
6,710,053 Deuterated rapamycin compounds, method and uses thereof 43 2002
6,884,429 Medical devices incorporating deuterated rapamycin for controlled delivery thereof 59 2002
 
MEDINOL LTD. (4)
5,449,373 Articulated stent 688 1994
6,315,794 Multilayered metal stent 161 1999
2006/0178,727 Hybrid amorphous metal alloy stent 45 2006
2007/0219,642 Hybrid stent having a fiber or wire backbone 30 2007
 
REGENTS OF THE UNIVERSITY OF MINNESOTA (4)
4,585,652 Electrochemical controlled release drug delivery system 185 1984
5,874,134 Production of nanostructured materials by hypersonic plasma particle deposition 74 1997
6,924,004 Apparatus and method for synthesizing films and coatings by focused particle beam deposition 38 2001
7,247,338 Coating medical devices 41 2002
 
SURMODICS, INC. (4)
2005/0019,371 Controlled release bioactive agent delivery device 69 2004
2005/0244,459 Coating compositions for bioactive agents 67 2005
2005/0196,424 Medical devices and methods for producing the same 60 2005
7,547,445 Crosslinkable macromers 43 2006
 
The United States of America as represented by the Secretary of the Navy (4)
5,242,706 Laser-deposited biocompatible films and methods and apparatuses for producing same 62 1991
5,380,298 Medical device with infection preventing feature 73 1993
6,025,036 Method of producing a film coating by matrix assisted pulsed laser deposition 64 1997
6,660,343 Fabrication of conductive/non-conductive nanocomposites by laser evaporation 16 2001
 
ABBOTT LABORATORIES (3)
7,208,190 Method of loading beneficial agent to a prosthesis by fluid-jet application 42 2003
2007/0191,943 Integration Of Therapeutic Agent Into A Bioerodible Medical Device 50 2006
2008/0057,103 METHODS OF USING MEDICAL DEVICES FOR CONTROLLED DRUG RELEASE 27 2007
 
ANGIOTECH PHARMACEUTICALS, INC. (3)
6,106,473 Echogenic coatings 180 1997
2002/0165,265 ANTI-ANGIOGENIC COMPOSITIONS AND METHODS OF USE 66 1997
6,846,841 Anti-angiogenic compositions and methods of use 60 2002
 
DEPUY PRODUCTS, INC. (3)
6,569,489 Bioactive ceramic coating and method 96 2000
6,736,849 Surface-mineralized spinal implants 47 2002
7,368,065 Implants with textured surface and methods for producing the same 52 2005
 
ICON INTERVENTIONAL SYSTEMS, INC. (3)
6,206,916 Coated intraluminal graft 150 1999
2002/0099,438 Irradiated stent coating 79 2001
2007/0032,864 Thrombosis inhibiting graft 49 2005
 
PRESIDENT AND FELLOWS OF HARVARD COLLEGE (3)
5,951,881 Fabrication of small-scale cylindrical articles 142 1996
6,776,094 Kit For Microcontact Printing 183 1998
2004/0178,523 Molded waveguides 35 2003
 
TERUMO KABUSHIKI KAISHA (3)
6,833,004 Stent 82 2002
2003/0181,975 Stent 54 2003
2003/0216,806 Stent 22 2003
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (3)
7,048,939 Methods for the inhibition of neointima formation 47 2002
7,056,339 Drug delivery platform 49 2002
7,981,441 Drug delivery systems using mesoporous oxide films 12 2004
 
UNIVERSITY OF CONNECTICUT (3)
2005/0010,275 Implantable medical devices 96 2003
2005/0216,074 Implantable medical devices 98 2004
2005/0251,249 Endoprostheses 56 2005
 
WARSAW ORTHOPEDIC, INC. (3)
6,323,146 Synthetic biomaterial compound of calcium phosphate phases particularly adapted for supporting bone cell activity 108 1998
2002/0138,146 Anterior expandable spinal fusion cage system 4 2002
2006/0229,715 Implants incorporating nanotubes and methods for producing the same 39 2005
 
ABBOTT LABORATORIES VASCULAR ENTERPRISES LIMITED (2)
2004/0133,270 Drug eluting stent and methods of manufacture 71 2003
2006/0155,361 Stent with rough surface and its manufacture 45 2003
 
ALCOVE SURFACES GMBH (2)
6,709,379 Implant with cavities containing therapeutic agents 220 2001
6,740,077 Implant with permeable element 57 2001
 
ALZA CORPORATION (2)
4,309,996 System with microporous releasing diffusor 120 1980
6,071,305 Directional drug delivery stent and method of use 412 1997
 
AMS MEDINVENT S.A. (2)
4,655,771 Prosthesis comprising an expansible or contractile tubular body 1354 1983
5,061,275 Self-expanding prosthesis 643 1989
 
Angiotech International AG (2)
2004/0219,214 Tissue reactive compounds and compositions and uses thereof 68 2003
2005/0165,467 Intravascular devices and fibrosis-inducing agents 25 2004
 
ATRIUM MEDICAL CORPORATION (2)
6,955,661 Expandable fluoropolymer device for delivery of therapeutic agents and method of making 68 1999
2003/0153,901 Drug delivery panel 56 2002
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (2)
2003/0050,687 Biocompatible stents and method of deployment 72 2001
7,238,199 Method and apparatus for stent deployment with enhanced delivery of bioactive agents 47 2002
 
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (2)
2003/0083,614 Controlled release endoprosthetic device 46 2002
2005/0192,664 Controlled release endoprosthetic device 43 2005
 
CaP Biotechnology, Inc. (2)
6,210,715 Calcium phosphate microcarriers and microspheres 127 2000
6,358,532 Calcium phosphate microcarriers and microspheres 42 2001
 
COOK INCORPORATED (2)
4,800,882 Endovascular stent and delivery system 1266 1987
2005/0159,804 Multiple stitches for attaching stent to graft 64 2005
 
COOK MEDICAL TECHNOLOGIES LLC (2)
2003/0028,243 Coated implantable medical device 264 2002
2005/0278,021 Coated medical device 76 2005
 
CORVITA CORPORATION (2)
4,738,740 Method of forming implantable vascular grafts 133 1985
4,743,252 Composite grafts 244 1986
 
DIMICRON, INC. (2)
6,488,715 Diamond-surfaced cup for use in a prosthetic joint 85 2000
6,514,289 Diamond articulation surface for use in a prosthetic joint 38 2000
 
ELECTROFORMED STENTS, INC. (2)
6,904,658 Process for forming a porous drug delivery layer 60 2003
2004/0237,282 Process for forming a porous drug delivery layer 45 2003
 
Exxon Research and Engineering Company (2)
4,407,695 Natural lithographic fabrication of microstructures over large areas 120 1982
5,852,088 Nanoporous ceramics with catalytic functionality 44 1995
 
FLAME-SPRAY INDUSTRIES, INC. (2)
6,139,913 Kinetic spray coating method and apparatus 115 1999
6,283,386 Kinetic spray coating apparatus 86 2000
 
GENERAL ELECTRIC COMPANY (2)
4,237,559 Bone implant embodying a composite high and low density fired ceramic construction 78 1979
6,180,184 Thermal barrier coatings having an improved columnar microstructure 31 1997
 
GENESIS MICROCHIP INC. (2)
6,973,718 Methods for conformal coating and sealing microchip reservoir devices 74 2002
2006/0093,646 Orthopedic and dental implant devices providing controlled drug delivery 64 2005
 
Harbor Medical Devices, Inc. (2)
5,447,724 Medical device polymer 427 1993
5,569,463 Medical device polymer 334 1995
 
ICON MEDICAL CORP. (2)
2007/0123,973 Biodegradable device 48 2006
2010/0042,206 BIOABSORBABLE COATINGS FOR MEDICAL DEVICES 52 2009
 
INFRAMAT CORPORATION (2)
2008/0069,854 MEDICAL DEVICES AND METHODS OF MAKING AND USING 49 2007
2008/0124,373 LUMEN - SUPPORTING DEVICES AND METHODS OF MAKING AND USING 45 2007
 
INTERNATIONAL BUSINESS MACHINES CORPORATION (2)
5,693,928 Method for producing a diffusion barrier and polymeric article having a diffusion barrier 47 1996
6,962,822 Discrete nano-textured structures in biomolecular arrays, and method of use 44 2002
 
KINIK COMPANY (2)
6,830,598 Molten braze coated superabrasive particles and associated methods 26 2002
7,261,752 Molten braze-coated superabrasive particles and associated methods 26 2003
 
KIPS BAY MEDICAL, INC. (2)
2005/0055,085 Implantable medical devices having recesses 51 2003
2006/0184,235 Implantable medical devices having recesses 43 2006
 
LUCENT TECHNOLOGIES INC. (2)
5,681,196 Spaced-gate emission device and method for making same 38 1995
6,504,292 Field emitting device comprising metallized nanostructures and method for making the same 118 1999
 
MEDTRONIC AVE, INC. (2)
5,290,585 Lubricious hydrogel coatings 128 1992
6,206,915 Drug storing and metering stent 154 1998
 
NANOSYS, INC. (2)
2005/0038,498 Medical device applications of nanostructured surfaces 150 2004
2005/0221,072 Medical device applications of nanostructured surfaces 113 2005
 
NICAST LTD. (2)
2004/0030,377 Medicated polymer-coated stent assembly 61 2003
7,244,272 Vascular prosthesis and method for production thereof 50 2005
 
Norman Noble, Inc., (2)
6,709,451 Channeled vascular stent apparatus and method 69 2000
2004/0181,275 Channeled vascular stent apparatus and method 43 2004
 
NOVOSTENT CORPORATION (2)
2004/0122,504 Vascular prosthesis and methods of use 51 2003
2004/0158,308 Delivery catheter for ribbon-type prosthesis and methods of use 43 2004
 
ORBUSNEICH MEDICAL, INC. (2)
2004/0039,441 Drug eluting implantable medical device 89 2003
2007/0129,789 Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device 44 2006
 
PFIZER INC. (2)
2005/0137,679 Modified stent useful for delivery of drugs along stent strut 45 2004
2005/0137,684 Stent with therapeutically active drug coated thereon 45 2004
 
PRECISION VASCULAR SYSTEMS, INC. (2)
6,214,042 Micro-machined stent for vessels, body ducts and the like 105 1998
6,063,101 Stent apparatus and method 198 1998
 
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (2)
5,587,507 Synthesis of tyrosine derived diphenol monomers 103 1995
6,475,477 Radio-opaque polymer biomaterials 96 2000
 
SPECTRA-PHYSICS, INC. (2)
2004/0000,540 Laser texturing of surfaces for biomedical implants 48 2003
2005/0211,680 Systems and methods for laser texturing of surfaces of a substrate 76 2005
 
STENT TECH, INC. (2)
5,858,556 Multilayer composite tubular structure and method of making 267 1997
2002/0133,222 Expandable stent having a plurality of interconnected expansion modules 49 2002
 
SYNTHEON, LLC (2)
6,527,938 Method for microporous surface modification of implantable metallic medical articles 92 2001
2003/0108,659 Implantable metallic medical articles having microporous surface structure 58 2003
 
The Boeing Company (2)
5,968,640 Conductive, thermally stable oligomers 28 1985
7,837,726 Visible endoprosthesis 58 2006
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (2)
2004/0026,811 Tissue engineering scaffolds 26 2002
2010/0130,346 METHOD OF PRESSURELESS SINTERING PRODUCTION OF DENSIFIED CERAMIC COMPOSITES 12 2009
 
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (2)
5,830,480 Stabilization of sol-gel derived silica-based glass 41 1996
2005/0019,265 Polymersomes incorporating highly emissive probes 49 2004
 
THORATEC CORPORATION (2)
6,327,504 Transcutaneous energy transfer with circuitry arranged to avoid overheating 64 2000
6,752,826 Layered stent-graft and methods of making the same 191 2001
 
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (2)
2002/0169,493 Anti-thrombogenic coatings for biomedical devices 45 2001
2004/0052,861 Sol-gel derived bioactive glass polymer composite 18 2003
 
WORLD HEART CORPORATION (2)
4,665,896 Power supply for body implant and method of use 138 1985
6,270,831 Method and apparatus for providing a conductive, amorphous non-stick coating 158 1998
 
XTENT, INC. (2)
2004/0243,217 Expandable stent 86 2004
2005/0228,477 Topographic coatings and coating methods for medical devices 80 2005
 
3M INNOVATIVE PROPERTIES COMPANY (1)
2002/0095,871 Method of making ceramic aggregate particles 36 2001
 
ABPS Venture One, Ltd. (1)
7,018,408 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 105 2003
 
Advanced Bio Prosthetic Surface, Ltd., a wholly owned subsidiary of Palmaz Scientific, Inc. (1)
7,195,641 Valvular prostheses having metal or pseudometallic construction and methods of manufacture 173 2002
 
ADVANCED LASER APPLICATIONS HOLDING S.A. (1)
2004/0006,382 Intraluminar perforated radially expandable drug delivery prosthesis 67 2003
 
AIR PRODUCTS AND CHEMICALS, INC. (1)
2002/0142,579 ORGANOSILICON PRECURSORS FOR INTERLAYER DIELECTRIC FILMS WITH LOW DIELECTRIC CONSTANTS 48 2001
 
Aita, Carolyn (1)
6,869,701 Self-repairing ceramic coatings 52 1999
 
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (1)
5,405,367 Structure and method of manufacture of an implantable microstimulator 325 1993
 
ALLIEDSIGNAL INC. (1)
6,022,812 Vapor deposition routes to nanoporous silica 46 1998
 
ANELVA CORPORATION (1)
6,878,249 High frequency sputtering device 43 2001
 
APPLIED MATERIALS, INC. (1)
6,367,412 Porous ceramic liner for a plasma source 55 2000
 
APPLIED MEDICAL RESOURCES CORPORATION (1)
2005/0113,936 Surface treatments and modifications using nanostructure materials 82 2004
 
APPLIED MICROSTRUCTURES, INC. (1)
2006/0088,666 Controlled vapor deposition of biocompatible coatings over surface-treated substrates 53 2005
 
AQUAMARIJN HOLDING B.V. (1)
2004/0028,875 Method of making a product with a micro or nano sized structure and product 145 2003
 
ASTELLAS PHARMA INC. (1)
2004/0117,008 Medical implants containing FK506 (tacrolimus), methods of making and methods of use thereof 77 2003
 
AZMED, LTD. (1)
2005/0251,245 Methods and apparatus with porous materials 48 2004
 
B. BRAUN-SSC AG (1)
4,902,290 Process for the preparation of a vessel prosthesis impregnated with crosslinked gelatin 81 1988
 
BADARI NAYANAN NAGARADA GADDE (1)
2004/0117,005 Stent with drug-delivery system 47 2004
 
BASF CORPORATION (1)
5,686,499 Polyurethane foams containing high levels of silicone-containing surfactant polymer to improve flame retardance and aged K-factors 24 1995
 
Battelle-Institut e.V. (1)
4,202,055 Anchorage for highly stressed endoprostheses 116 1977
 
BAYER MATERIALSCIENCE AG (1)
6,599,558 Treating metal surfaces to enhance bio-compatibility and/or physical characteristics 57 1999
 
BEST MEDICAL INTERNATIONAL, INC. (1)
6,709,397 Scanning probe 56 2002
 
BIOCER ENTWICKLUNGS GMBH (1)
2009/0317,766 Structured coatings for implants and process for the preparation thereof 28 2007
 
BIOSENSORS INTERNATIONAL USA (1)
2003/0088,307 Potent coatings for stents 145 2002
 
BIOTRONIK AG (1)
6,287,332 Implantable, bioresorbable vessel wall support, in particular coronary stent 233 1999
 
BIOTRONIK IV PATENT AG (1)
2006/0052,864 Endoprosthesis comprising a magnesium alloy 54 2005
 
BIOTRONIK VI PATENT AG (1)
2006/0052,863 Endoprosthesis comprising a magnesium alloy 49 2005
 
BLERSCH, JUERGEN, DR. (1)
2005/0079,201 Implants with functionalized carbon surfaces 43 2004
 
BLUE MEDICAL DEVICES B.V. (1)
2008/0050,413 Medical stent provided with a combination of melatonin and paclitaxel 44 2006
 
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (1)
7,311,727 Encased stent 52 2004
 
BODYCOTE ORTECH INC. (1)
4,475,972 Implantable material 151 1982
 
BOSTON SCIENTIFIC LIMITED (1)
6,335,029 Polymeric coatings for controlled delivery of active agents 421 1998
 
BRIDGE BLOOD TECHNOLOGIES LLC, NEW YORK LIMITED LIABILITY COMPANY (1)
5,322,520 Iontophoretic structure for medical devices 179 1992
 
Calcitec, Inc. (1)
2007/0213,827 Hardened calcium phosphate cement bone implants 26 2006
 
CAMBRIDGE POLYMER GROUP, INC. (1)
2004/0092,653 Systems and methods for controlling and forming polymer gels 52 2003
 
CAPHCO, INC. (1)
5,788,687 Compositions and devices for controlled release of active ingredients 76 1995
 
CASE WESTERN RESERVE UNIVERSITY (1)
2003/0118,649 Drug delivery devices and methods 62 2002
 
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (1)
6,468,304 Implantable device covered with polymer capable of releasing biologically active substances 56 2000
 
CERNOFINA, LLC (1)
7,087,661 Safe and effective biofilm inhibitory compounds and health-related uses thereof 31 1999
 
CINVENTION AG (1)
2006/0171,990 Drug delivery materials made by sol/gel technology 18 2006
 
COCHLEAR LIMITED (1)
5,279,292 Charging system for implantable hearing aids and tinnitus maskers 220 1992
 
CODMAN & SHURTLEFF, INC. (1)
6,955,685 Expandable stent with radiopaque markers and stent delivery system 93 2003
 
COMMISSARIAT A L'ENERGIE ATOMIQUE (1)
2006/0141,156 Surface-coating method 56 2004
 
CONOR MEDSYSTEMS, INC. (1)
7,208,011 Implantable medical device with drug filled holes 73 2002
 
CONTROL DELIVERY SYSTEMS, INC. (1)
2003/0158,598 System for sustained-release delivery of anti-inflammatory agents from a coated medical device 85 2003
 
CORNELL UNIVERSITY (1)
5,219,611 Preparing densified low porosity titania sol gel forms 37 1991
 
CV THERAPEUTICS, INC. (1)
7,160,592 Polymer coating for medical devices 58 2003
 
DAI NIPPON PRINTING CO., LTD. (1)
5,679,440 Optical card 50 1995
 
DEBIOTECH S.A. (1)
2009/0177,273 ANISOTROPIC NANOPOROUS COATINGS FOR MEDICAL IMPLANTS 43 2007
 
DELCATH SYSTEMS, INC. (1)
5,817,046 Apparatus and method for isolated pelvic perfusion 87 1997
 
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Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (1)
8,663,317 Intraluminar perforated radially expandable drug delivery prosthesis and a method for the production thereof 0 2012

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