US Patent No: 8,187,620

Number of patents in Portfolio can not be more than 2000

Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents

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Abstract

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The invention relates generally to a medical device, such as an intravascular stent, for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. More particularly, the invention pertains to a medical device having a metal oxide or metal material with a plurality of pores therein disposed on the surface of the medical device and a polymer disposed on the metal oxide or metal material. The invention also relates to medical devices having a surface and an outer region comprising a metal oxide or metal material having a plurality of pores therein and a polymer disposed on the metal oxide or metal material.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BOSTON SCIENTIFIC SCIMED, INC.MAPLE GROVE, MN4603

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chandrasekaran, Chandru Mercer Island, US 10 302
Radhakrishnan, Rajesh Bothell, US 57 309

Cited Art Landscape

Patent Info (Count) # Cites Year
 
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Other [Check patent profile for assignment information] (54)
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DONALD G. KEACH, PH.D., DIRECTOR OF INTELLECTUAL PROPERTY DEVELOPMENT, UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (1)
2003/0047,505 Tubular filter with branched nanoporous membrane integrated with a support and method of producing same 35 2002
 
GELSUS RESEARCH AND CONSULTINH INC. (1)
6,699,282 Method and apparatus for delivery of medication 51 2003
 
THOMAS, JAMES C., JR. (1)
2003/0074,075 Expandable implant for partial disc replacement and reinforcement of a disc partially removed in a discectomy and for reduction and maintenance of alignment of cancellous bone fractures and methods and apparatuses for same 230 2002
 
SONY CORPORATION (1)
2007/0052,497 Mems type oscillator, process for fabricating the same, filter, and communication unit 47 2004
 
FOAMIX PHARMACEUTICALS LTD. (1)
2006/0088,561 Pharmaceutical composition for topical application 63 2005
 
INDUSTRIAL RESEARCH LIMITED (1)
2003/0167,878 Titanium-containing materials 39 2003
 
Harbor Medical Devices, Inc. (2)
5,447,724 Medical device polymer 460 1993
5,569,463 Medical device polymer 360 1995
 
UNIVERSITY TECHNOLOGY CORPORATION (1)
2003/0074,081 Non-uniform porosity tissue implant 50 2002
 
ZIMMER GMBH (1)
2004/0016,651 Method for the manufacture of an implant, a method for the decontamination of a surface treated with blasting particles and a medical implant 28 2003
 
GENE-TRAK SYSTEMS CORPORATION (1)
5,073,365 Clinical and personal care articles enhanced by lubricants and adjuvants 88 1989
 
WISCONSIN ALUMNI RESEARCH FOUNDATION (1)
2006/0251,701 Localized delivery of nucleic acid by polyelectrolyte assemblies 57 2006
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (2)
2003/0050,687 Biocompatible stents and method of deployment 81 2001
7,238,199 Method and apparatus for stent deployment with enhanced delivery of bioactive agents 52 2002
 
PFIZER INC. (2)
2005/0137,679 Modified stent useful for delivery of drugs along stent strut 49 2004
2005/0137,684 Stent with therapeutically active drug coated thereon 50 2004
 
GREATBATCH LTD. (1)
2006/0200,231 Stent Coating For Eluting Medication 56 2006
 
SHIRKHANZADEH, MORTEZA (1)
5,205,921 Method for depositing bioactive coatings on conductive substrates 120 1991
 
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (1)
5,405,367 Structure and method of manufacture of an implantable microstimulator 381 1993
 
SYNTHEON, LLC (2)
6,527,938 Method for microporous surface modification of implantable metallic medical articles 102 2001
2003/0108,659 Implantable metallic medical articles having microporous surface structure 64 2003
 
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (2)
2003/0083,614 Controlled release endoprosthetic device 50 2002
2005/0192,664 Controlled release endoprosthetic device 46 2005
 
ASTELLAS PHARMA INC. (1)
2004/0117,008 Medical implants containing FK506 (tacrolimus), methods of making and methods of use thereof 89 2003
 
UNIVERSITY OF CONNECTICUT (3)
2005/0010,275 Implantable medical devices 110 2003
2005/0216,074 Implantable medical devices 113 2004
2005/0251,249 Endoprostheses 71 2005
 
SYNTHES USA, LLC (1)
7,494,950 Bone cement compositions having fiber-reinforcement and/or increased flowability 41 2004
 
UNIVERSITY OF VIRGINIA (15)
7,294,409 Medical devices having porous layers and methods for making same 51 2003
2005/0070,989 Medical devices having porous layers and methods for making the same 64 2004
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2006/0193,886 Medical devices with nanoporous layers and topcoats 63 2006
2006/0193,887 Medical devices having nanoporous bonding layers 55 2006
2006/0193,888 Methods for using medical devices having nanoporous layers 56 2006
2006/0193,889 Nanoporous layers using thermal dealloying 55 2006
2006/0193,890 Method for loading nanoporous layers with therapeutic agent 70 2006
2006/0276,877 Dealloyed nanoporous stents 63 2006
2006/0276,878 Dealloyed nanoporous stents 56 2006
2006/0276,884 Nanoporous stents with magnesium leaching 53 2006
2006/0276,885 Nanoporous stents with improved radiolucency 54 2006
2006/0271,169 Stent with nanoporous surface 51 2006
2006/0276,879 Medical devices having porous layers and methods for making the same 52 2006
2008/0086,198 NANOPOROUS STENTS WITH ENHANCED CELLULAR ADHESION AND REDUCED NEOINTIMAL FORMATION 26 2007
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (1)
5,891,192 Ion-implanted protein-coated intralumenal implants 183 1997
 
CORDIS CORPORATION (19)
4,994,071 Bifurcating stent apparatus and method 1001 1989
5,163,958 Carbon coated tubular endoprosthesis 422 1991
5,891,108 Drug delivery stent 220 1994
5,882,335 Retrievable drug delivery stent 161 1996
6,273,913 Modified stent useful for delivery of drugs along stent strut 643 1998
5,902,266 Method for delivering a liquid solution to the interior wall surface of a vessel 164 1998
2001/0014,821 BALLOON CATHETER AND STENT DELIVERY SYSTEM HAVING ENHANCED STENT RETENTION 58 1998
6,325,825 Stent with variable wall thickness 158 1999
6,153,252 Process for coating stents 710 1999
6,315,708 Stent with self-expanding end sections 98 2000
2002/0051,730 Coated medical devices and sterilization thereof 305 2001
6,776,022 Stent with variable wall thickness 58 2001
6,852,122 Coated endovascular AAA device 91 2003
2005/0137,677 Endovascular graft with differentiable porosity along its length 85 2003
2004/0236,416 Increased biocompatibility of implantable medical devices 64 2004
2006/0200,229 Geometry and material for use in high strength, high flexibility, controlled recoil drug eluting stents 50 2005
2008/0086,199 BIOABSORBABLE DEVICE HAVING COMPOSITE STRUCTURE FOR ACCELERATING DEGRADATION 68 2006
2008/0152,929 POLYMER COATING FOR MEDICAL DEVICES 45 2006
2010/0131,050 ABSORBABLE STENT HAVING A COATING FOR CONTROLLING DEGRADATION OF THE STENT AND MAINTAINING pH NEUTRALITY 46 2008
 
Endovascular Devices, Inc. (1)
7,396,538 Apparatus and method for delivery of mitomycin through an eluting biocompatible implantable medical device 32 2003
 
NANOSURFACE TECHNOLOGIES LLC (1)
2009/0186,068 Atomic plasma deposited coatings for drug release 26 2008
 
UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (1)
4,308,868 Implantable electrical device 82 1980
 
PETER RICHTER (1)
5,302,414 Gas-dynamic spraying method for applying a coating 273 1992
 
THE UNIVERSITY OF BRITISH COLUMBIA (1)
2006/0199,876 Bioceramic composite coatings and process for making same 69 2005
 
FURST, GARY H. (1)
6,436,133 Expandable graft 86 1999
 
NANOSYS, INC. (2)
2005/0038,498 Medical device applications of nanostructured surfaces 191 2004
2005/0221,072 Medical device applications of nanostructured surfaces 135 2005
 
GLOBALFOUNDRIES INC. (1)
6,962,822 Discrete nano-textured structures in biomolecular arrays, and method of use 48 2002
 
UNIVERSITY OF WASHINGTON (1)
6,558,422 Structures having coated indentations 94 2000
 
JUNGSUNG MEDICAL CO., LTD. (1)
6,875,227 Metal stent for insertion in coronary artery 62 2002
 
CONTROL DELIVERY SYSTEMS, INC. (1)
2003/0158,598 System for sustained-release delivery of anti-inflammatory agents from a coated medical device 94 2003
 
SPIRE CORPORATION (1)
5,474,797 Bactericidal coatings for implants 102 1994
 
NANOTEK INSTRUMENTS, INC. (1)
6,465,052 Method for production of nano-porous coatings 32 2001
 
NANOTHERAPEUTICS, INC. (1)
7,063,748 Methods for coating particles and particles produced thereby 49 2002
 
DUKE UNIVERSITY (1)
5,527,337 Bioabsorbable stent and method of making the same 445 1994
 
B. BRAUN-SSC AG (1)
4,902,290 Process for the preparation of a vessel prosthesis impregnated with crosslinked gelatin 84 1988
 
Ionbond, Inc. (1)
7,393,589 Dual layer diffusion bonded chemical vapor coating for medical implants 47 2005
 
ELIXIR MEDICAL CORPORATION (1)
2006/0229,711 Degradable implantable medical devices 90 2006
 
PG-TXL Company, L.P. (1)
6,730,699 Water soluble paclitaxel derivatives 108 2002
 
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6,869,701 Self-repairing ceramic coatings 57 1999
 
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7,208,190 Method of loading beneficial agent to a prosthesis by fluid-jet application 46 2003
2007/0191,943 Integration Of Therapeutic Agent Into A Bioerodible Medical Device 55 2006
2008/0057,103 METHODS OF USING MEDICAL DEVICES FOR CONTROLLED DRUG RELEASE 33 2007
 
Abbott Laboratories Vascular Enterprises Limited (2)
2004/0133,270 Drug eluting stent and methods of manufacture 82 2003
2006/0155,361 Stent with rough surface and its manufacture 50 2003
 
Innovative Materials Processing Technologies Limited (1)
6,331,330 Film or coating deposition and powder formation 34 1998
 
STOUT MEDICAL GROUP, INC. (1)
2003/0211,135 Stent having electrospun covering and method 87 2002
 
UNIVERSITE CATHOLIQUE DE LOUVAIN (1)
5,962,136 Biomaterial and method for obtaining it 41 1997
 
Lathrotec, Inc. (1)
5,120,322 Method and apparatus for treatment of fibrotic lesions 180 1990
 
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6,479,418 Porous ceramic body 39 2000
 
Abbott Cardiovascular Systems Inc. (5)
2003/0083,731 Manufacture of fine-grained material for use in medical devices 63 2001
7,691,461 Hybrid stent and method of making 43 2002
8,029,816 Medical device coated with a coating containing elastin pentapeptide VGVPG 17 2007
2008/0306,584 Implantable medical devices for local and regional treatment 47 2007
7,901,452 Method to fabricate a stent having selected morphology to reduce restenosis 20 2007
 
BASF CORPORATION (1)
5,686,499 Polyurethane foams containing high levels of silicone-containing surfactant polymer to improve flame retardance and aged K-factors 25 1995
 
APPLIED MEDICAL RESOURCES CORPORATION (1)
2005/0113,936 Surface treatments and modifications using nanostructure materials 98 2004
 
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2005/0019,371 Controlled release bioactive agent delivery device 80 2004
2005/0244,459 Coating compositions for bioactive agents 79 2005
2005/0196,424 Medical devices and methods for producing the same 66 2005
7,547,445 Crosslinkable macromers 47 2006
 
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4,954,126 Prosthesis comprising an expansible or contractile tubular body 793 1989
 
KIM, SUCK JOON (1)
2002/0042,039 Image storage system for dental treatment 47 2001
 
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6,106,473 Echogenic coatings 209 1997
2002/0165,265 ANTI-ANGIOGENIC COMPOSITIONS AND METHODS OF USE 69 1997
6,846,841 Anti-angiogenic compositions and methods of use 63 2002
 
ANGIOTECH INTERNATIONAL AG (2)
2004/0219,214 Tissue reactive compounds and compositions and uses thereof 90 2003
2005/0165,467 Intravascular devices and fibrosis-inducing agents 65 2004
 
EPION CORPORATION (1)
6,416,820 Method for forming carbonaceous hard film 45 1999
 
BAYER MATERIALSCIENCE AG (1)
6,599,558 Treating metal surfaces to enhance bio-compatibility and/or physical characteristics 63 1999
 
FINSBURY (DEVELOPMENT) LIMITED (1)
7,497,876 Prosthetic implant 32 2004
 
STRYKER TECHNOLOGIES CORPORATION (1)
5,326,354 Method for forming attachment surfaces on implants 47 1993
 
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2006/0292,388 Low texture, quasi-isotropic metallic stent 47 2005
 
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6,709,451 Channeled vascular stent apparatus and method 75 2000
2004/0181,275 Channeled vascular stent apparatus and method 46 2004
 
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2006/0088,666 Controlled vapor deposition of biocompatible coatings over surface-treated substrates 58 2005
 
ELUTEX LTD. (1)
2006/0013,850 Electropolymerizable monomers and polymeric coatings on implantable devices prepared therefrom 59 2005
 
UNIVERSITY OF BATH (1)
2009/0220,612 HOLLOW-FIBRE-BASED BIOCOMPATIBLE DRUG DELIVERY DEVICE WITH ONE OR MORE LAYERS 51 2006
 
THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (1)
5,744,515 Method and implantable article for promoting endothelialization 203 1996
 
ROCKWELL INTERNATIONAL CORPORATION (1)
4,565,744 Wettable coating for reinforcement particles of metal matrix composite 38 1983
 
PHARMED HOLDING GMBH (1)
2002/0072,734 Chip systems for the controlled emission of substances having a chemosensory effect 44 2001
 
ORMCO CORPORATION (1)
5,378,146 Polyurethane biomedical devices & method of making same 40 1992
 
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (1)
7,311,727 Encased stent 58 2004
 
HERAEUS PRECIOUS METALS GMBH & CO. KG (1)
2008/0038,146 Metal alloy for medical devices and implants 49 2007
 
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6,569,489 Bioactive ceramic coating and method 105 2000
6,736,849 Surface-mineralized spinal implants 53 2002
7,368,065 Implants with textured surface and methods for producing the same 67 2005
 
DEPUY ORTHOPAEDICS, INC. (1)
6,193,761 Implantable prosthesis with metallic porous bead preforms applied during casting 52 1996
 
INTEGRATED DEVICE TECHNOLOGY, INC. (1)
5,672,242 High selectivity nitride to oxide etch process 46 1996
 
ETEX CORPORATION (1)
2007/0128,245 Porous calcium phosphate bone material 43 2005
 
INTERMEDICAT GMBH, GERLISWILSTRASSE 74, CH-6020 EMMENBRUCKE, SWITZERLAND, (1)
4,784,659 Vessel and prosthesis impregnated with diisocyanate crosslinked gelatin 95 1987
 
Rehberg; Christoph (1)
6,034,295 Implantable device having an internal electrode for stimulating growth of tissue 89 1996
 
WYETH (10)
7,261,735 Local drug delivery devices and methods for maintaining the drug coatings thereon 61 2001
7,195,640 Coated medical devices for the treatment of vulnerable plaque 77 2002
2004/0002,755 Method and apparatus for treating vulnerable coronary plaques using drug-eluting stents 34 2002
2003/0204,168 Coated vascular devices 153 2002
2004/0167,572 Coated medical devices 420 2003
2005/0136,090 Local vascular delivery of trichostatin a alone or in combination with sirolimus to prevent restenosis following vascular injury 76 2003
2005/0004,663 Heparin barrier coating for controlled drug release 104 2004
2005/0033,417 Coating for controlled release of a therapeutic agent 75 2004
2006/0129,225 Device for the delivery of a cardioprotective agent to ischemic reperfused myocardium 76 2004
2007/0135,908 Absorbable stent comprising coating for controlling degradation and maintaining pH neutrality 55 2005
 
Lutonix, Inc. (1)
2008/0255,508 DRUG RELEASING COATINGS FOR MEDICAL DEVICES 81 2008
 
EXXON RESEARCH & ENGINEERING CO. (2)
4,407,695 Natural lithographic fabrication of microstructures over large areas 128 1982
5,852,088 Nanoporous ceramics with catalytic functionality 48 1995
 
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5,807,407 Medical implant device and method for making same 40 1992
 
ICON MEDICAL CORP. (2)
2007/0123,973 Biodegradable device 56 2006
2010/0042,206 BIOABSORBABLE COATINGS FOR MEDICAL DEVICES 57 2009
 
APPLIED MATERIALS, INC. (1)
6,367,412 Porous ceramic liner for a plasma source 63 2000
 
BOSTON SCIENTIFIC SCIMED, INC. (231)
5,195,969 Co-extruded medical balloons and catheter using such balloons 308 1991
5,270,086 Multilayer extrusion of angioplasty balloons 442 1991
5,304,121 Drug delivery system making use of a hydrogel polymer coating 612 1991
5,366,504 Tubular medical prosthesis 479 1992
5,674,192 Drug delivery 253 1993
5,397,307 Drug delivery PTCA catheter and method for drug delivery 171 1993
5,449,382 Minimally invasive bioactivated endoprosthesis for vessel repair 414 1994
5,439,446 Stent and therapeutic delivery system 311 1994
6,017,577 Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices 105 1995
5,578,075 Minimally invasive bioactivated endoprosthesis for vessel repair 277 1995
5,824,077 Clad composite stent 155 1995
6,524,274 Triggered release hydrogel drug delivery system 132 1995
6,171,609 Therapeutic inhibitor of vascular smooth muscle cells 202 1995
5,772,864 Method for manufacturing implantable medical devices 171 1996
5,837,313 Drug release stent coating process 737 1996
6,120,536 Medical devices with long term non-thrombogenic coatings 636 1996
5,824,045 Vascular and endoluminal stents 227 1996
5,733,925 Therapeutic inhibitor of vascular smooth muscle cells 441 1996
6,306,144 Selective coating of a balloon catheter with lubricious material for stent deployment 102 1996
5,788,979 Biodegradable coating with inhibitory properties for application to biocompatible materials 394 1997
5,922,021 Intravascular stent 263 1997
5,879,697 Drug-releasing coatings for medical devices 219 1997
5,980,564 Bioabsorbable implantable endoprosthesis with reservoir 241 1997
6,174,330 Bioabsorbable marker having radiopaque constituents 342 1997
5,972,027 Porous stent drug delivery system 402 1997
6,290,721 Tubular medical endoprostheses 309 1997
6,099,562 Drug coating with topcoat 597 1997
6,358,556 Drug release stent coating 421 1998
5,980,566 Vascular and endoluminal stents with iridium oxide coating 118 1998
6,287,331 Tubular medical prosthesis 114 1998
2002/0032,477 DRUG RELEASE COATED STENT 107 1998
6,280,411 Localized delivery of drug agents 190 1998
6,652,581 Medical device with porous surface for controlled drug release and method of making the same 85 1998
6,099,561 Vascular and endoluminal stents with improved coatings 323 1998
6,159,142 Stent with radioactive coating for treating blood vessels to prevent restenosis 91 1998
6,419,692 Surface protection method for stents and balloon catheters for drug delivery 389 1999
6,245,104 Method of fabricating a biocompatible stent 112 1999
6,249,952 Method for manufacturing an expandable stent 110 1999
6,231,600 Stents with hybrid coating for medical devices 394 1999
6,217,607 Premounted stent delivery system for small vessels 62 1999
6,652,582 Bioabsorbable endoprosthesis having porosity for by-product collection 87 1999
6,253,443 Method of forming a stent 198 1999
6,440,503 Laser deposition of elements onto medical devices 49 2000
6,368,658 Coating medical devices using air suspension 284 2000
6,726,712 Prosthesis deployment device with translucent distal end 164 2000
6,284,305 Drug coating with topcoat 287 2000
6,387,121 Vascular and endoluminal stents with improved coatings 217 2000
6,478,815 Vascular and endoluminal stents 105 2000
6,491,666 Microfabricated devices for the delivery of molecules into a carrier fluid 241 2000
6,517,888 Method for manufacturing a medical device having a coated portion by laser ablation 187 2000
6,545,097 Drug delivery compositions and medical devices containing block copolymer 265 2000
6,398,806 Monolayer modification to gold coated stents to reduce adsorption of protein 62 2000
6,752,829 Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same 105 2001
6,767,360 Vascular stent with composite structure for magnetic reasonance imaging capabilities 77 2001
6,607,598 Device for protecting medical devices during a coating process 78 2001
6,783,543 Intravascular stent with increasing coating retaining capacity 137 2001
2001/0029,660 Stent drug delivery system 79 2001
6,939,320 Localized delivery of drug agents 111 2001
6,676,987 Coating a medical appliance with a bubble jet printing head 122 2001
6,620,194 Drug coating with topcoat 71 2001
6,669,980 Method for spray-coating medical devices 202 2001
6,764,709 Method for making and measuring a coating on the surface of a medical device using an ultraviolet laser 59 2001
6,807,440 Ceramic reinforcement members for MRI devices 47 2001
7,014,654 Stent designed for the delivery of therapeutic substance or other agents 50 2001
2003/0153,971 Metal reinforced biodegradable intraluminal stents 93 2002
2002/0144,757 Stainless steel alloy with improved radiopaque characteristics 70 2002
2003/0018,380 Platinum enhanced alloy and intravascular or implantable medical devices manufactured therefrom 90 2002
2003/0077,200 Enhanced radiopaque alloy stent 82 2002
2003/0236,514 Implantable or insertable medical devices for controlled delivery of a therapeutic agent 90 2002
2004/0022,824 Controlled drug delivery 37 2002
7,101,391 Primarily niobium stent 52 2002
6,908,622 Optimized dosing for drug coated stents 75 2002
7,060,051 Multi-balloon catheter with hydrogel coating 95 2002
2004/0059,409 Method of applying coatings to a medical device 80 2002
6,971,813 Contact coating of prostheses 75 2002
2004/0098,089 Medical devices 54 2002
2004/0106,987 Medical devices for delivery of therapeutic agents 96 2002
6,803,070 Apparatus and method for embedding nanoparticles in polymeric medical devices 51 2002
2004/0143,317 Medical devices 180 2003
7,402,173 Metal stent with surface layer of noble metal oxide and method of fabrication 49 2003
2004/0106,985 Intravascular stent 100 2003
2004/0093,071 Intravascular stent with increasing coating retaining capacity 60 2003
7,482,034 Expandable mask stent coating method 35 2003
7,101,394 Energetically-controlled delivery of biologically active material from an implanted medical device 57 2003
2004/0230,290 Medical devices and methods of making the same 66 2003
2004/0234,748 Electrostatic coating of a device 61 2003
7,011,680 Stent device and method 65 2003
2004/0225,347 Intravascular stent with increasing coating retaining capacity 33 2003
7,052,488 Implantable drug delivery device 87 2003
2005/0037,047 Medical devices comprising spray dried microparticles 95 2003
7,713,297 Drug-releasing stent with ceramic-containing layer 46 2003
2004/0039,438 Vascular and endoluminal stents with multi-layer coating including porous radiopaque layer 75 2003
* 2005/0060,021 Medical devices 63 2003
2005/0060,020 Covered stent with biologically active material 148 2003
2005/0070,990 Medical devices and methods of making same 68 2003
2004/0067,301 Medical device with porous surface for controlled drug release and method of making the same 50 2003
2005/0074,479 Using bucky paper as a therapeutic aid in medical applications 48 2003
2005/0087,520 Method and apparatus for selective ablation of coatings from medical devices 55 2003
7,435,256 Method and apparatus for controlled delivery of active substance 27 2003
2004/0181,276 Longitudinally flexible expandable stent 48 2003
2005/0131,522 Medical devices and methods of making the same 119 2003
2005/0149,102 Medical device systems 41 2003
2005/0159,805 Functional coatings and designs for medical implants 52 2004
2005/0163,954 Medical devices 70 2004
7,041,130 Stent for controlled release of drug 95 2004
2005/0129,727 Localized drug delivery using drug-loaded nanocapsules 77 2004
2005/0182,478 Laser shock peening of medical devices 48 2004
2005/0192,657 Medical devices 66 2004
2005/0196,518 Method and system for making a coated medical device 46 2004
2005/0015,142 Coated medical device and method for manufacturing the same 53 2004
2005/0203,606 Stent system for preventing restenosis 62 2004
2005/0208,100 Medical articles having regions with polyelectrolyte multilayer coatings for regulating drug release 90 2004
6,861,088 Method for spray-coating a medical device having a tubular wall such as a stent 158 2004
2005/0220,853 Controlled delivery of therapeutic agents from medical articles 59 2004
2004/0247,671 Solid drug formulation and device for storage and controlled delivery thereof 71 2004
2005/0266,039 Coated medical device and method for making the same 48 2004
2005/0266,040 Medical devices composed of porous metallic materials for delivering biologically active materials 53 2004
2006/0025,848 Medical device having a coating layer with structural elements therein and method of making the same 64 2004
* 2006/0034,884 Coated medical device having an increased coating surface area 35 2004
2006/0052,744 Method of coating a medical device using an electrowetting process, system for using the method, and device made by the method 66 2004
2006/0079,863 Medical devices coated with diamond-like carbon 34 2004
2005/0110,214 Composite stent with inner and outer stent elements and method of using the same 39 2004
2006/0088,566 Method of controlling drug release from a coated medical device through the use of nucleating agents 58 2004
2006/0088,567 Method of manufacturing a medical device having a porous coating thereon 48 2004
2006/0093,643 Medical device for delivering therapeutic agents over different time periods 54 2004
2006/0095,123 Stent for delivering a therapeutic agent having increased body tissue contact surface 36 2004
2006/0100,696 Medical devices and methods of making the same 53 2004
2006/0122,694 Medical devices and methods of making the same 57 2004
2006/0127,443 Medical devices having vapor deposited nanoporous coatings for controlled therapeutic agent delivery 70 2004
2006/0129,215 Medical devices having nanostructured regions for controlled tissue biocompatibility and drug delivery 72 2004
2006/0125,144 Stent and stent manufacturing methods 29 2004
2005/0197,687 Medical devices including metallic films and methods for making same 55 2004
2005/0197,689 Medical devices including metallic films and methods for making same 33 2004
2006/0153,729 Medical devices and methods of making the same 66 2005
2006/0171,985 Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility 48 2005
2006/0230,476 Polymeric/ceramic composite materials for use in medical devices 78 2005
2006/0222,844 Medical devices including composites 55 2005
2006/0233,941 Method of coating a medical device utilizing an ion-based thin film deposition technique, a system for coating a medical device, and a medical device produced by the method 51 2005
2005/0261,760 Medical devices and methods of making the same 80 2005
2006/0276,910 Endoprostheses 30 2005
2007/0038,176 Medical devices with machined layers for controlled communications with underlying regions 51 2005
7,914,809 Lubricious composites for medical devices 16 2005
2007/0048,452 Apparatus and method for field-injection electrostatic spray coating of medical devices 33 2005
2007/0072,978 Organic-inorganic hybrid particle material and polymer compositions containing same 29 2005
2006/0038,027 Apparatus and method for fine bore orifice spray coating of medical devices and pre-filming atomization 67 2005
2007/0110,888 Coated and imprinted medical devices and methods of making the same 37 2005
2007/0112,421 Medical device with a grooved surface 42 2005
2007/0134,288 Anti-adhesion agents for drug coatings 51 2005
2007/0154,513 Medical devices having multiple charged layers 33 2005
2007/0156,231 Bioerodible endoprostheses and methods of making the same 57 2006
2007/0190,104 Coating comprising an adhesive polymeric material for a medical device and method of preparing the same 53 2006
2007/0191,923 Medical balloons and methods of making the same 52 2006
2007/0191,931 Bioerodible endoprostheses and methods of making the same 51 2006
2007/0212,547 Method of powder coating medical devices 37 2006
2007/0224,244 Corrosion resistant coatings for biodegradable metallic implants 59 2006
2007/0224,235 Medical devices having nanoporous coatings for controlled therapeutic agent delivery 42 2006
2007/0224,116 Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents 48 2006
2007/0244,569 Endoprosthesis having a fiber meshwork disposed thereon 56 2006
2007/0254,091 System and method for electrostatic-assisted spray coating of a medical device 33 2006
2007/0264,303 Coating for medical devices comprising an inorganic or ceramic oxide and a therapeutic agent 51 2006
2007/0269,480 Medical devices having bioactive surfaces 28 2006
2008/0003,251 Coatings for medical devices comprising a therapeutic agent and a metallic material 53 2006
2008/0008,654 Medical devices having a temporary radiopaque coating 65 2006
2008/0058,921 IMPROVED ADHESION OF A POLYMERIC COATING OF A DRUG ELUTING STENT 47 2006
2008/0188,836 Medical devices having nanoporous coatings for controlled therapeutic agent delivery 45 2007
2008/0249,615 STENTS WITH CERAMIC DRUG RESERVOIR LAYER AND METHODS OF MAKING AND USING THE SAME 45 2007
2008/0249,600 STENTS WITH DRUG RESERVOIR LAYER AND METHODS OF MAKING AND USING THE SAME 47 2007
2008/0051,881 Medical devices comprising porous layers for the release of therapeutic agents 60 2007
2008/0275,543 Stent 28 2007
2008/0294,236 Endoprosthesis with Select Ceramic and Polymer Coatings 50 2007
2008/0294,246 Endoprosthesis with Select Ceramic Morphology 52 2007
2008/0050,415 Polymeric/ceramic composite materials for use in medical devices 37 2007
2008/0004,691 MEDICAL DEVICES WITH SELECTIVE COATING 51 2007
2009/0018,639 ENDOPROSTHESIS COATING 46 2007
2009/0018,647 ENDOPROSTHESIS COATING 47 2007
2009/0018,644 Boron-Enhanced Shape Memory Endoprostheses 30 2007
2008/0160,259 MEDICAL DEVICES AND METHODS OF MAKING THE SAME 55 2007
2009/0030,504 Medical devices comprising porous inorganic fibers for the release of therapeutic agents 52 2007
2009/0138,077 Articles having ceramic coated surfaces 51 2007
2007/0299,509 MEDICAL DEVICE WITH POROUS SURFACE FOR CONTROLLED DRUG RELEASE AND METHOD OF MAKING THE SAME 45 2007
2008/0071,355 Medical Devices with Drug-Eluting Coating 64 2007
2008/0071,348 Medical Devices 46 2007
2008/0071,349 Medical Devices 52 2007
2008/0071,350 ENDOPROSTHESES 56 2007
2008/0071,358 ENDOPROSTHESES 55 2007
2009/0076,588 Endoprosthesis 52 2007
2008/0071,351 ENDOPROSTHESIS WITH ADJUSTABLE SURFACE FEATURES 49 2007
2008/0071,352 BIOERODIBLE ENDOPROSTHESIS WITH BIOSTABLE INORGANIC LAYERS 49 2007
2008/0071,353 ENDOPROSTHESIS CONTAINING MAGNETIC INDUCTION PARTICLES 47 2007
2008/0086,201 MAGNETIZED BIOERODIBLE ENDOPROSTHESIS 47 2007
2009/0076,595 Medical devices having bioerodable layers for the release of therapeutic agents 39 2007
2008/0097,577 MEDICAL DEVICE HYDROGEN SURFACE TREATMENT BY ELECTROCHEMICAL REDUCTION 49 2007
2008/0147,177 ENDOPROSTHESIS WITH COATINGS 57 2007
2008/0145,400 Ion Bombardment of Medical Devices 46 2007
2009/0118,809 ENDOPROSTHESIS WITH POROUS RESERVOIR AND NON-POLYMER DIFFUSION LAYER 46 2007
2009/0118,812 ENDOPROSTHESIS COATING 46 2007
2009/0118,813 NANO-PATTERNED IMPLANT SURFACES 46 2007
2009/0118,814 ENDOPROSTHESIS COATING 46 2007
2009/0118,815 STENT 46 2007
2009/0118,818 ENDOPROSTHESIS WITH COATING 45 2007
2009/0118,820 DEFORMABLE UNDERLAYER FOR STENT 45 2007
2009/0118,821 ENDOPROSTHESIS WITH POROUS RESERVOIR AND NON-POLYMER DIFFUSION LAYER 48 2007
2009/0118,822 STENT WITH EMBEDDED MATERIAL 47 2007
2009/0118,823 ENDOPROSTHESIS WITH POROUS RESERVOIR 48 2007
2009/0123,521 Medical devices having coatings for controlled therapeutic agent delivery 60 2007
7,749,264 Medical devices and methods of making the same 46 2008
2008/0241,218 Coated medical devices for abluminal drug delivery 46 2008
2008/0243,231 Medical device with a porous surface for delivery of a therapeutic agent 58 2008
2009/0018,642 Methods to improve the stability of celluar adhesive proteins and peptides 26 2008
2008/0255,657 STENT WITH UNCONNECTED STENT SEGMENTS 26 2008
2009/0123,517 MEDICAL DEVICES FOR RELEASING THERAPEUTIC AGENT AND METHODS OF MAKING THE SAME 47 2008
2009/0281,613 Endoprostheses 47 2008
2009/0287,301 Coating for medical implants 46 2008
2009/0306,765 Bioerodible Endoprosthesis 46 2008
2009/0012,603 IMPLANTABLE MEDICAL DEVICES HAVING ADJUSTABLE PORE VOLUME AND METHODS FOR MAKING THE SAME 27 2008
2009/0149,942 ENDOPROSTHESIS HAVING A NON-FOULING SURFACE 46 2008
2009/0028,785 MEDICAL DEVICES WITH COATINGS FOR DELIVERY OF A THERAPEUTIC AGENT 46 2008
2009/0157,172 STENTS WITH POLYMER-FREE COATINGS FOR DELIVERING A THERAPEUTIC AGENT 54 2008
2010/0030,326 Bioerodible Endoprosthesis 45 2008
2009/0157,165 Degradable Endoprosthesis 47 2008
2009/0157,166 Medical Devices Having Porous Component For Controlled Diffusion 32 2008
2010/0008,970 Drug-Eluting Endoprosthesis 49 2008
2009/0192,593 Stent for Delivery a Therapeutic Agent from a Side Surface of a Stent StSrut 41 2009
2009/0202,610 Medical Implants With Polysaccharide Drug Eluting Coatings 48 2009
2009/0259,300 Medical Devices With an Interlocking Coating and Methods of Making the Same 47 2009
2009/0264,975 MEDICAL DEVICES HAVING A COATING OF INORGANIC MATERIAL 33 2009
2009/0319,032 ENDOPROSTHESIS COATING 24 2009
2010/0028,403 MEDICAL DEVICES FOR THERAPEUTIC AGENT DELIVERY 18 2009
2010/0057,197 MEDICAL DEVICES HAVING INORGANIC COATINGS FOR THERAPEUTIC AGENT DELIVERY 59 2009
2010/0070,022 LAYER BY LAYER MANUFACTURING OF A STENT 38 2009
7,922,756 Stent 19 2010
 
DEPUY INC. (1)
5,368,881 Prosthesis with highly convoluted surface 61 1993
 
BOSTON SCIENTIFIC LIMITED (1)
6,335,029 Polymeric coatings for controlled delivery of active agents 474 1998
 
ICON INTERVENTIONAL SYSTEMS, INC. (3)
6,206,916 Coated intraluminal graft 164 1999
2002/0099,438 Irradiated stent coating 90 2001
2007/0032,864 Thrombosis inhibiting graft 54 2005
 
BOSTON SCIENTIFIC CORPORATION (5)
5,954,706 Drug delivery 165 1995
5,843,089 Stent lining 213 1996
5,928,247 Stent placement device with medication dispenser and method 54 1997
6,364,856 Medical device with sponge coating for controlled drug release 203 1998
5,968,092 Method for making a biodegradable stent 163 1998
 
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (2)
5,587,507 Synthesis of tyrosine derived diphenol monomers 119 1995
6,475,477 Radio-opaque polymer biomaterials 113 2000
 
BODYCOTE ORTECH INC. (1)
4,475,972 Implantable material 164 1982
 
TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (1)
2008/0290,467 SEMICONDUCTOR MEMORY STRUCTURES 46 2007
 
GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE, THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (1)
5,711,866 Acid assisted cold welding and intermetallic formation and dental applications thereof 34 1995
 
SIEMENS ENERGY, INC. (1)
6,365,222 Abradable coating applied with cold spray technique 40 2000
 
PANASONIC LIQUID CRYSTAL DISPLAY CO., LTD. (1)
7,099,091 Display device 45 2003
 
MEDINOL LTD. (4)
5,449,373 Articulated stent 729 1994
6,315,794 Multilayered metal stent 181 1999
2006/0178,727 Hybrid amorphous metal alloy stent 56 2006
2007/0219,642 Hybrid stent having a fiber or wire backbone 46 2007
 
SCIMED LIFE SYSTEMS, INC. (15)
5,464,450 Biodegradable drug delivery vascular stent 297 1994
5,551,954 Biodegradable drug delivery vascular stent 310 1994
5,500,013 Biodegradable drug delivery vascular stent 364 1995
5,769,883 Biodegradable drug delivery vascular stent 330 1995
6,387,124 Biodegradable drug delivery vascular stent 122 1999
6,395,325 Porous membranes 79 2000
2002/0138,136 Medical device having radio-opacification and barrier layers 89 2001
2002/0065,553 Method for manufacturing a medical device having a coated portion by laser ablation 153 2001
6,652,575 Stent with smooth ends 129 2001
6,869,443 Biodegradable drug delivery vascular stent 142 2002
2004/0086,674 Laser sintering process and devices made therefrom 44 2002
2004/0098,119 Stent with smooth ends 51 2003
2006/0127,442 Use of supercritical fluids to incorporate biologically active agents into nanoporous medical articles 38 2004
2005/0278,016 Stent designed for the delivery of therapeutic substance or other agents 64 2005
2006/0264,138 Composite ePTFE/textile prosthesis 50 2006
 
HITACHI, LTD. (1)
2005/0186,696 Gas flowmeter and manufacturing method thereof 0 2005
 
XTENT, INC. (2)
2004/0243,217 Expandable stent 98 2004
2005/0228,477 Topographic coatings and coating methods for medical devices 95 2005
 
INFLOW DYNAMICS (1)
6,613,083 Stent device and method 68 2001
 
INNERDYNE, INC. (1)
6,613,432 Plasma-deposited coatings, devices and methods 128 2000
 
Quanam Medical Corporation (1)
5,674,242 Endoprosthetic device with therapeutic compound 431 1996
 
UNIVERSIDADE DO PORTO (1)
2007/0224,224 Protozoan Strains of Reduced Virulence and Use Thereof 26 2004
 
CONOR MEDSYSTEMS, INC. (1)
7,208,011 Implantable medical device with drug filled holes 79 2002
 
BIOTRONIK IV PATENT AG (1)
2006/0052,864 Endoprosthesis comprising a magnesium alloy 63 2005
 
BIOTRONIK AG (1)
6,287,332 Implantable, bioresorbable vessel wall support, in particular coronary stent 272 1999
 
INTERNATIONAL BUSINESS MACHINES CORPORATION (1)
5,693,928 Method for producing a diffusion barrier and polymeric article having a diffusion barrier 50 1996
 
Silicon Genesis Corporation (1)
6,120,660 Removable liner design for plasma immersion ion implantation 77 1998
 
SIEMENS AKTIENGESELLSCHAFT (1)
7,643,885 Intravenous pacemaker electrode 16 2005
 
LEPU MEDICAL TECHNOLOGY (BEIJING) CO., LTD. (1)
2009/0112,310 Nanoporous Drug Release Structure for Drug Elute Instruments and the Preparation Method Thereof 35 2007
 
USBIOMATERIALS CORPORATION (1)
5,977,204 Biodegradable implant material comprising bioactive ceramic 115 1997
 
BIOTRONIK VI PATENT AG (1)
2006/0052,863 Endoprosthesis comprising a magnesium alloy 59 2005
 
Innovative Technology, Inc. (1)
5,795,626 Coating or ablation applicator with a debris recovery attachment 129 1996
 
SG Licensing Corporation (1)
6,337,076 Method and composition for the treatment of scars 50 1999
 
SORIN BIOMEDICA S.P.A. (1)
6,491,720 Angioplasty stent adapted to counter restenosis respective kit and components 56 2000
 
KIPS BAY MEDICAL, INC. (2)
2005/0055,085 Implantable medical devices having recesses 55 2003
2006/0184,235 Implantable medical devices having recesses 46 2006
 
SORIN BIOMEDICA CARDIO S.R.L. (5)
2004/0167,612 Process for producing stents and corresponding stents 49 2004
2007/0065,418 Method and device for cellular therapy 47 2006
2007/0219,626 Stents made of biodegradable and non-biodegradable materials 50 2007
2007/0191,928 Angioplasty stents 46 2007
2008/0288,048 STENTS FOR ANGIOPLASTY 45 2007
 
SPECTRA-PHYSICS, INC. (2)
2004/0000,540 Laser texturing of surfaces for biomedical implants 52 2003
2005/0211,680 Systems and methods for laser texturing of surfaces of a substrate 91 2005
 
SORIN BIOMEDICA CARDIO S.P.A. (1)
2003/0125,803 Carrier and kit for intraluminal delivery of active principles or agents 95 2002
 
Nicast Ltd. (2)
2004/0030,377 Medicated polymer-coated stent assembly 86 2003
7,244,272 Vascular prosthesis and method for production thereof 58 2005
 
ABPS VENTURE ONE, LTD. (4)
6,458,153 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 493 1999
6,652,578 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 332 2001
2003/0023,300 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 215 2002
2006/0167,543 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 146 2006
 
SYNECOR LLC (1)
6,932,930 Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same 85 2003
 
ROBERT BOSCH GMBH (1)
4,825,696 Acceleration detector 20 1987
 
The Kendall Company (1)
4,705,502 Suprapubic catheter with dual balloons 127 1986
 
VENTURE LENDING & LEASING IV, INC. (1)
2002/0077,693 Covered, coiled drug delivery stent and method 250 2000
 
MED INSTITUTE, INC. (8)
5,609,629 Coated implantable medical device 734 1995
* 6,096,070 Coated implantable medical device 890 1996
5,824,049 Coated implantable medical device 847 1996
5,873,904 Silver implantable medical device 832 1997
6,530,951 Silver implantable medical device 360 1997
6,299,604 Coated implantable medical device 719 1999
6,918,927 Coated implantable medical device 193 2001
2007/0073,385 Eluting, implantable medical device 82 2006
 
CALCITEC, INC. (1)
2007/0213,827 Hardened calcium phosphate cement bone implants 32 2006
 
TOSHIBA TEC KABUSHIKI KAISHA (1)
2006/0075,092 System and method for determining the status of users and devices from access log information 50 2004
 
SMITH & NEPHEW RICHARDS INC. (1)
5,649,951 Zirconium oxide and zirconium nitride coated stents 141 1995
 
GE HEALTHCARE AS (1)
2005/0002,865 Diagnostic/therapeutic agents 57 2003
 
CORVITA CORPORATION (2)
4,738,740 Method of forming implantable vascular grafts 140 1985
4,743,252 Composite grafts 259 1986
 
ADVANCED BIO PROSTHETIC SURFACES, LTD. (22)
6,190,404 Intravascular stent and method for manufacturing an intravascular stent 126 1998
6,379,383 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 250 1999
6,537,310 Endoluminal implantable devices and method of making same 155 2000
6,820,676 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 85 2000
2001/0001,834 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 66 2000
6,849,085 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and method of making same 139 2001
2001/0032,013 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and method of making same 204 2001
6,695,865 Embolic protection device 167 2002
6,936,066 Complaint implantable medical devices and methods of making same 151 2002
2002/0165,600 Guidewires and thin film catheter-sheaths and method of making same 70 2002
2003/0059,640 High strength vacuum deposited nitinol alloy films and method of making same 120 2002
2003/0074,053 Endoluminal implantable stent-grafts 54 2002
2003/0130,718 Endoluminal implantable stent-grafts 75 2002
6,923,829 Implantable expandable medical devices having regions of differential mechanical properties and methods of making same 48 2002
2004/0181,252 Balloon catheter having metal balloon and method of making same 70 2003
7,018,408 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 127 2003
7,235,098 Medical devices having MEMs functionality and methods of making same 50 2004
2005/0072,544 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 46 2004
2005/0131,521 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and methods of making same 45 2005
2005/0165,468 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and methods of making same 55 2005
2005/0232,968 Implantable materials having engineered surfaces and method of making same 47 2005
2006/0015,175 Compliant implantable medical devices and methods of making same 46 2005
 
Cinvention AG (1)
2006/0171,990 Drug delivery materials made by sol/gel technology 22 2006
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (73)
5,649,977 Metal reinforced polymer stent 522 1994
5,605,696 Drug loaded polymeric material and method of manufacture 672 1995
6,174,329 Protective coating for a stent with intermediate radiopaque coating 221 1996
5,780,807 Method and apparatus for direct laser cutting of metal stents 393 1997
5,843,172 Porous medicated stent 412 1997
6,240,616 Method of manufacturing a medicated porous metal prosthesis 472 1997
6,287,628 Porous prosthesis and a method of depositing substances into the pores 367 1999
6,251,136 Method of layering a three-coated stent using pharmacological and polymeric agents 353 1999
6,471,721 Vascular stent having increased radiopacity and method for making same 129 1999
6,527,801 Biodegradable drug delivery material for stent 333 2000
6,395,326 Apparatus and method for depositing a coating onto a surface of a prosthesis 499 2000
6,585,765 Implantable device having substances impregnated therein and a method of impregnating the same 276 2000
6,254,632 Implantable medical device having protruding surface structures for drug delivery and cover attachment 506 2000
6,716,444 Barriers for polymer-coated implantable medical devices and methods for making the same 295 2000
6,805,898 Surface features of an implantable medical device 200 2000
6,506,437 Methods of coating an implantable device having depots formed in a surface thereof 371 2000
6,558,733 Method for etching a micropatterned microdepot prosthesis 314 2000
6,663,664 Self-expanding stent with time variable radial force 111 2000
6,758,859 Increased drug-loading and reduced stress drug delivery device 272 2000
6,913,617 Method for creating a textured surface on an implantable medical device 70 2000
6,663,662 Diffusion barrier layer for implantable devices 293 2000
6,790,228 Coating for implantable devices and a method of forming the same 242 2000
2001/0014,717 Coating for implantable devices and a method of forming the same 217 2000
2002/0123,801 Diffusion barrier layer for implantable devices 200 2000
6,635,082 Radiopaque stent 94 2000
6,641,607 Double tube stent 98 2000
2002/0087,123 Adhesion of heparin-containing coatings to blood-contacting surfaces of medical devices 195 2001
6,544,582 Method and apparatus for coating an implantable device 264 2001
6,780,424 Controlled morphologies in polymer drug for release of drugs from polymer films 119 2001
6,673,105 Metal prosthesis coated with expandable ePTFE 81 2001
6,764,505 Variable surface area stent 322 2001
6,712,845 Coating for a stent and a method of forming the same 298 2001
2002/0155,212 Coating for a stent and a method of forming the same 242 2001
6,660,034 Stent for increasing blood flow to ischemic tissues and a method of using the same 274 2001
6,656,506 Microparticle coated medical device 216 2001
2002/0183,581 Radiation or drug delivery source with activity gradient to minimize edge effects 218 2001
6,712,844 MRI compatible stent 80 2001
2003/0004,563 Polymeric stent suitable for imaging by MRI and fluoroscopy 109 2001
6,979,346 System and method for improved stent retention 78 2001
6,753,071 Rate-reducing membrane for release of an agent 296 2001
2003/0104,028 Rate limiting barriers for implantable devices and methods for fabrication thereof 70 2001
6,866,805 Hybrid intravascular stent 105 2001
6,616,765 Apparatus and method for depositing a coating onto a surface of a prosthesis 238 2002
6,723,120 Medicated porous metal prosthesis 226 2002
* 2004/0088,038 Porous metal for drug-loaded stents 86 2002
7,169,178 Stent with drug coating 80 2002
6,908,624 Coating for implantable devices and a method of forming the same 121 2002
6,725,901 Methods of manufacture of fully consolidated or porous medical devices 65 2002
6,896,697 Intravascular stent 79 2002
7,105,018 Drug-eluting stent cover and method of use 77 2002
7,163,715 Spray processing of porous medical devices 99 2002
2004/0224,001 Stent coatings comprising hydrophilic additives 125 2003
6,846,323 Intravascular stent 179 2003
2004/0230,293 INTRAVASCULAR STENT 101 2003
2005/0021,127 Porous glass fused onto stent for drug retention 63 2003
7,056,591 Hydrophobic biologically absorbable coatings for drug delivery devices and methods for fabricating the same 67 2003
7,247,166 Intravascular stent with extendible end rings 29 2003
7,198,675 Stent mandrel fixture and method for selectively coating surfaces of a stent 65 2003
2005/0069,630 Stent mandrel fixture and method for selectively coating surfaces of a stent 82 2003
6,953,560 Barriers for polymer-coated implantable medical devices and methods for making the same 74 2003
7,563,324 System and method for coating an implantable medical device 48 2003
2004/0234,737 Rate-reducing membrane for release of an agent 52 2004
7,229,471 Compositions containing fast-leaching plasticizers for improved performance of medical devices 83 2004
2006/0136,048 Abluminal, multilayer coating constructs for drug-delivery stents 73 2004
7,638,156 Apparatus and method for selectively coating a medical article 29 2005
2007/0148,251 Nanoparticle releasing medical devices 61 2005
2007/0003,589 Coatings for implantable medical devices containing attractants for endothelial cells 63 2006
7,416,558 Drug-eluting stent cover and method of use 48 2006
2007/0032,858 Stent with drug coating 49 2006
2007/0036,905 Method and apparatus for spray processing of porous medical devices 52 2006
2007/0055,349 Stent with drug coating 47 2006
2007/0055,354 Stent with drug coating 45 2006
2007/0059,435 Stent with drug coating 45 2006
 
Vascular Concepts Holdings Limited (1)
2006/0224,234 Drug eluting structurally variable stent 77 2006
 
IMEDD, INC. (1)
2003/0064,095 Microfabricated nanopore device for sustained release of therapeutic agent 73 2002
 
CV THERAPEUTICS, INC. (1)
7,160,592 Polymer coating for medical devices 70 2003
 
ADVANCED BIO PROSTHETIC SURFACE, LTD (1)
7,195,641 Valvular prostheses having metal or pseudometallic construction and methods of manufacture 221 2002
 
WORLD HEART CORPORATION (2)
4,665,896 Power supply for body implant and method of use 151 1985
6,270,831 Method and apparatus for providing a conductive, amorphous non-stick coating 194 1998
 
FLAME-SPRAY INDUSTRIES, INC. (2)
6,139,913 Kinetic spray coating method and apparatus 126 1999
6,283,386 Kinetic spray coating apparatus 91 2000
 
Imperial Innovations Limited (1)
2009/0208,428 Bioactive Glass 61 2007
 
COOK MEDICAL TECHNOLOGIES LLC (2)
2003/0028,243 Coated implantable medical device 292 2002
2005/0278,021 Coated medical device 103 2005
 
TINI ALLOY COMPANY (1)
5,061,914 Shape-memory alloy micro-actuator 348 1989
 
ANELVA CORPORATION (1)
6,878,249 High frequency sputtering device 46 2001
 
XOFT, INC. (1)
6,390,967 Radiation for inhibiting hyperplasia after intravascular intervention 96 2000
 
EXOGENESIS CORPORATION (1)
6,676,989 Method and system for improving the effectiveness of medical stents by the application of gas cluster ion beam technology 63 2001
 
GENERAL ELECTRIC COMPANY (1)
6,180,184 Thermal barrier coatings having an improved columnar microstructure 34 1997
 
SUMMERS, DAVID (1)
5,980,551 Composition and method for making a biodegradable drug delivery stent 184 1997
 
AZMED, LTD. (1)
2005/0251,245 Methods and apparatus with porous materials 52 2004
 
F.W. GARTNER THERMAL SPRAYING, LTD. (1)
2006/0275,554 High performance kinetic spray nozzle 47 2006
 
GENESIS MICROCHIP INC. (2)
6,973,718 Methods for conformal coating and sealing microchip reservoir devices 91 2002
2006/0093,646 Orthopedic and dental implant devices providing controlled drug delivery 85 2005
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (3)
7,048,939 Methods for the inhibition of neointima formation 50 2002
7,056,339 Drug delivery platform 53 2002
7,981,441 Drug delivery systems using mesoporous oxide films 15 2004
 
Advanced BioProsthetic Surfaces, Ltd. (1)
6,733,513 Balloon catheter having metal balloon and method of making same 125 2002
 
Guardian Industries Corp. (1)
6,764,579 Solar management coating system including protective DLC 67 2002
 
Delpor, Inc. (1)
2005/0118,229 Implantable drug delivery device for sustained release of therapeutic agent 27 2004
 
RADIOVASCULR, INC. (1)
2002/0077,520 Device and method for dilating and irradiating a vascular segment or body passageway 32 2000
 
STRYKER EUROPEAN HOLDINGS I, LLC (1)
7,169,177 Bifurcated stent 45 2003
 
ENZON, INC. (1)
5,614,549 High molecular weight polymer-based prodrugs 152 1995
 
AIR PRODUCTS AND CHEMICALS, INC. (1)
2002/0142,579 ORGANOSILICON PRECURSORS FOR INTERLAYER DIELECTRIC FILMS WITH LOW DIELECTRIC CONSTANTS 53 2001
 
CASE WESTERN RESERVE UNIVERSITY (1)
2003/0118,649 Drug delivery devices and methods 80 2002
 
EGAN VISUAL INC. (1)
2003/0170,605 Vapor deposited writing surfaces 46 2002
 
UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (1)
5,091,205 Hydrophilic lubricious coatings 354 1989
 
LIFESHIELD SCIENCES LLC (10)
4,657,544 Cardiovascular graft and method of forming same 107 1984
5,693,085 Stent with collagen 545 1995
5,758,562 Process for manufacturing braided composite prosthesis 122 1996
5,741,331 Biostable elastomeric polymers having quaternary carbons 146 1996
6,391,052 Stent with collagen 182 1997
5,968,091 Stents and stent grafts having enhanced hoop strength and methods of making the same 260 1997
6,139,573 Conformal laminate stent device 151 1998
6,514,283 Intraluminal lining 166 2001
6,827,737 EPTFE covering for endovascular prostheses and method of manufacture 74 2001
2004/0158,312 Braided endoluminal device having tapered filaments 16 2003
 
NEUROGEN CORPORATION (1)
5,266,698 Certain aryl and cycloalkyl fused imidazopyrazinediones; a new class of GABA brain receptor ligands 27 1992
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (2)
* 8,663,317 Intraluminar perforated radially expandable drug delivery prosthesis and a method for the production thereof 0 2012
* 2013/0004,650 Intraluminar perforated radially expandable drug delivery prosthesis and a method for the production thereof 2 2012
* Cited By Examiner

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