US Patent No: 8,187,620

Number of patents in Portfolio can not be more than 2000

Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents

ALSO PUBLISHED AS: 20070224116

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Abstract

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The invention relates generally to a medical device, such as an intravascular stent, for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. More particularly, the invention pertains to a medical device having a metal oxide or metal material with a plurality of pores therein disposed on the surface of the medical device and a polymer disposed on the metal oxide or metal material. The invention also relates to medical devices having a surface and an outer region comprising a metal oxide or metal material having a plurality of pores therein and a polymer disposed on the metal oxide or metal material.

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First Claim

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all claims..

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BOSTON SCIENTIFIC SCIMED, INC.MAPLE GROVE, MN4564

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chandrasekaran, Chandru Mercer Island, WA 15 264
Radhakrishnan, Rajesh Brampton, CA 65 256

Cited Art Landscape

Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (231)
5,195,969 Co-extruded medical balloons and catheter using such balloons 295 1991
5,270,086 Multilayer extrusion of angioplasty balloons 399 1991
5,304,121 Drug delivery system making use of a hydrogel polymer coating 519 1991
5,366,504 Tubular medical prosthesis 454 1992
5,674,192 Drug delivery 219 1993
5,397,307 Drug delivery PTCA catheter and method for drug delivery 165 1993
5,449,382 Minimally invasive bioactivated endoprosthesis for vessel repair 381 1994
5,439,446 Stent and therapeutic delivery system 279 1994
6,017,577 Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices 96 1995
5,578,075 Minimally invasive bioactivated endoprosthesis for vessel repair 261 1995
5,824,077 Clad composite stent 142 1995
6,524,274 Triggered release hydrogel drug delivery system 111 1995
6,171,609 Therapeutic inhibitor of vascular smooth muscle cells 189 1995
5,772,864 Method for manufacturing implantable medical devices 162 1996
5,837,313 Drug release stent coating process 674 1996
6,120,536 Medical devices with long term non-thrombogenic coatings 574 1996
5,824,045 Vascular and endoluminal stents 218 1996
5,733,925 Therapeutic inhibitor of vascular smooth muscle cells 397 1996
6,306,144 Selective coating of a balloon catheter with lubricious material for stent deployment 89 1996
5,788,979 Biodegradable coating with inhibitory properties for application to biocompatible materials 365 1997
5,922,021 Intravascular stent 244 1997
5,879,697 Drug-releasing coatings for medical devices 199 1997
5,980,564 Bioabsorbable implantable endoprosthesis with reservoir 212 1997
6,174,330 Bioabsorbable marker having radiopaque constituents 295 1997
5,972,027 Porous stent drug delivery system 375 1997
6,290,721 Tubular medical endoprostheses 271 1997
6,099,562 Drug coating with topcoat 561 1997
6,358,556 Drug release stent coating 394 1998
5,980,566 Vascular and endoluminal stents with iridium oxide coating 115 1998
6,287,331 Tubular medical prosthesis 96 1998
2002/0032,477 DRUG RELEASE COATED STENT 97 1998
6,280,411 Localized delivery of drug agents 164 1998
6,652,581 Medical device with porous surface for controlled drug release and method of making the same 79 1998
6,099,561 Vascular and endoluminal stents with improved coatings 304 1998
6,159,142 Stent with radioactive coating for treating blood vessels to prevent restenosis 89 1998
6,419,692 Surface protection method for stents and balloon catheters for drug delivery 345 1999
6,245,104 Method of fabricating a biocompatible stent 106 1999
6,249,952 Method for manufacturing an expandable stent 103 1999
6,231,600 Stents with hybrid coating for medical devices 373 1999
6,217,607 Premounted stent delivery system for small vessels 57 1999
6,652,582 Bioabsorbable endoprosthesis having porosity for by-product collection 77 1999
6,253,443 Method of forming a stent 189 1999
6,440,503 Laser deposition of elements onto medical devices 47 2000
6,368,658 Coating medical devices using air suspension 262 2000
6,726,712 Prosthesis deployment device with translucent distal end 136 2000
6,284,305 Drug coating with topcoat 270 2000
6,387,121 Vascular and endoluminal stents with improved coatings 208 2000
6,478,815 Vascular and endoluminal stents 97 2000
6,491,666 Microfabricated devices for the delivery of molecules into a carrier fluid 221 2000
6,517,888 Method for manufacturing a medical device having a coated portion by laser ablation 165 2000
6,545,097 Drug delivery compositions and medical devices containing block copolymer 240 2000
6,398,806 Monolayer modification to gold coated stents to reduce adsorption of protein 57 2000
6,752,829 Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same 96 2001
6,767,360 Vascular stent with composite structure for magnetic reasonance imaging capabilities 72 2001
6,607,598 Device for protecting medical devices during a coating process 74 2001
6,783,543 Intravascular stent with increasing coating retaining capacity 124 2001
2001/0029,660 Stent drug delivery system 76 2001
6,939,320 Localized delivery of drug agents 89 2001
6,676,987 Coating a medical appliance with a bubble jet printing head 109 2001
6,620,194 Drug coating with topcoat 66 2001
6,669,980 Method for spray-coating medical devices 179 2001
6,764,709 Method for making and measuring a coating on the surface of a medical device using an ultraviolet laser 56 2001
6,807,440 Ceramic reinforcement members for MRI devices 45 2001
7,014,654 Stent designed for the delivery of therapeutic substance or other agents 43 2001
2003/0153,971 Metal reinforced biodegradable intraluminal stents 73 2002
2002/0144,757 Stainless steel alloy with improved radiopaque characteristics 63 2002
2003/0018,380 Platinum enhanced alloy and intravascular or implantable medical devices manufactured therefrom 79 2002
2003/0077,200 Enhanced radiopaque alloy stent 73 2002
2003/0236,514 Implantable or insertable medical devices for controlled delivery of a therapeutic agent 77 2002
2004/0022,824 Controlled drug delivery 29 2002
7,101,391 Primarily niobium stent 50 2002
6,908,622 Optimized dosing for drug coated stents 70 2002
7,060,051 Multi-balloon catheter with hydrogel coating 76 2002
2004/0059,409 Method of applying coatings to a medical device 73 2002
6,971,813 Contact coating of prostheses 72 2002
2004/0098,089 Medical devices 52 2002
2004/0106,987 Medical devices for delivery of therapeutic agents 82 2002
6,803,070 Apparatus and method for embedding nanoparticles in polymeric medical devices 49 2002
2004/0143,317 Medical devices 159 2003
7,402,173 Metal stent with surface layer of noble metal oxide and method of fabrication 47 2003
2004/0106,985 Intravascular stent 92 2003
2004/0093,071 Intravascular stent with increasing coating retaining capacity 53 2003
7,482,034 Expandable mask stent coating method 31 2003
7,101,394 Energetically-controlled delivery of biologically active material from an implanted medical device 52 2003
2004/0230,290 Medical devices and methods of making the same 60 2003
2004/0234,748 Electrostatic coating of a device 46 2003
7,011,680 Stent device and method 59 2003
2004/0225,347 Intravascular stent with increasing coating retaining capacity 25 2003
7,052,488 Implantable drug delivery device 80 2003
2005/0037,047 Medical devices comprising spray dried microparticles 90 2003
7,713,297 Drug-releasing stent with ceramic-containing layer 44 2003
2004/0039,438 Vascular and endoluminal stents with multi-layer coating including porous radiopaque layer 71 2003
* 2005/0060,021 Medical devices 59 2003
2005/0060,020 Covered stent with biologically active material 134 2003
2005/0070,990 Medical devices and methods of making same 62 2003
2004/0067,301 Medical device with porous surface for controlled drug release and method of making the same 48 2003
2005/0074,479 Using bucky paper as a therapeutic aid in medical applications 46 2003
2005/0087,520 Method and apparatus for selective ablation of coatings from medical devices 47 2003
7,435,256 Method and apparatus for controlled delivery of active substance 24 2003
2004/0181,276 Longitudinally flexible expandable stent 46 2003
2005/0131,522 Medical devices and methods of making the same 102 2003
2005/0149,102 Medical device systems 36 2003
2005/0159,805 Functional coatings and designs for medical implants 49 2004
2005/0163,954 Medical devices 60 2004
7,041,130 Stent for controlled release of drug 83 2004
2005/0129,727 Localized drug delivery using drug-loaded nanocapsules 67 2004
2005/0182,478 Laser shock peening of medical devices 45 2004
2005/0192,657 Medical devices 59 2004
2005/0196,518 Method and system for making a coated medical device 38 2004
2005/0015,142 Coated medical device and method for manufacturing the same 50 2004
2005/0203,606 Stent system for preventing restenosis 42 2004
2005/0208,100 Medical articles having regions with polyelectrolyte multilayer coatings for regulating drug release 83 2004
6,861,088 Method for spray-coating a medical device having a tubular wall such as a stent 143 2004
2005/0220,853 Controlled delivery of therapeutic agents from medical articles 53 2004
2004/0247,671 Solid drug formulation and device for storage and controlled delivery thereof 69 2004
2005/0266,039 Coated medical device and method for making the same 46 2004
2005/0266,040 Medical devices composed of porous metallic materials for delivering biologically active materials 50 2004
2006/0025,848 Medical device having a coating layer with structural elements therein and method of making the same 59 2004
* 2006/0034,884 Coated medical device having an increased coating surface area 32 2004
2006/0052,744 Method of coating a medical device using an electrowetting process, system for using the method, and device made by the method 55 2004
2006/0079,863 Medical devices coated with diamond-like carbon 32 2004
2005/0110,214 Composite stent with inner and outer stent elements and method of using the same 33 2004
2006/0088,566 Method of controlling drug release from a coated medical device through the use of nucleating agents 50 2004
2006/0088,567 Method of manufacturing a medical device having a porous coating thereon 46 2004
2006/0093,643 Medical device for delivering therapeutic agents over different time periods 47 2004
2006/0095,123 Stent for delivering a therapeutic agent having increased body tissue contact surface 29 2004
2006/0100,696 Medical devices and methods of making the same 50 2004
2006/0122,694 Medical devices and methods of making the same 53 2004
2006/0127,443 Medical devices having vapor deposited nanoporous coatings for controlled therapeutic agent delivery 66 2004
2006/0129,215 Medical devices having nanostructured regions for controlled tissue biocompatibility and drug delivery 66 2004
2006/0125,144 Stent and stent manufacturing methods 25 2004
2005/0197,687 Medical devices including metallic films and methods for making same 49 2004
2005/0197,689 Medical devices including metallic films and methods for making same 29 2004
2006/0153,729 Medical devices and methods of making the same 58 2005
2006/0171,985 Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility 40 2005
2006/0230,476 Polymeric/ceramic composite materials for use in medical devices 65 2005
2006/0222,844 Medical devices including composites 49 2005
2006/0233,941 Method of coating a medical device utilizing an ion-based thin film deposition technique, a system for coating a medical device, and a medical device produced by the method 49 2005
2005/0261,760 Medical devices and methods of making the same 75 2005
2006/0276,910 Endoprostheses 27 2005
2007/0038,176 Medical devices with machined layers for controlled communications with underlying regions 48 2005
7,914,809 Lubricious composites for medical devices 13 2005
2007/0048,452 Apparatus and method for field-injection electrostatic spray coating of medical devices 31 2005
2007/0072,978 Organic-inorganic hybrid particle material and polymer compositions containing same 26 2005
2006/0038,027 Apparatus and method for fine bore orifice spray coating of medical devices and pre-filming atomization 58 2005
2007/0110,888 Coated and imprinted medical devices and methods of making the same 35 2005
2007/0112,421 Medical device with a grooved surface 35 2005
2007/0134,288 Anti-adhesion agents for drug coatings 49 2005
2007/0154,513 Medical devices having multiple charged layers 29 2005
2007/0156,231 Bioerodible endoprostheses and methods of making the same 53 2006
2007/0190,104 Coating comprising an adhesive polymeric material for a medical device and method of preparing the same 48 2006
2007/0191,923 Medical balloons and methods of making the same 48 2006
2007/0191,931 Bioerodible endoprostheses and methods of making the same 49 2006
2007/0212,547 Method of powder coating medical devices 34 2006
2007/0224,244 Corrosion resistant coatings for biodegradable metallic implants 55 2006
2007/0224,235 Medical devices having nanoporous coatings for controlled therapeutic agent delivery 36 2006
2007/0224,116 Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents 46 2006
2007/0244,569 Endoprosthesis having a fiber meshwork disposed thereon 50 2006
2007/0254,091 System and method for electrostatic-assisted spray coating of a medical device 28 2006
2007/0264,303 Coating for medical devices comprising an inorganic or ceramic oxide and a therapeutic agent 47 2006
2007/0269,480 Medical devices having bioactive surfaces 26 2006
2008/0003,251 Coatings for medical devices comprising a therapeutic agent and a metallic material 50 2006
2008/0008,654 Medical devices having a temporary radiopaque coating 57 2006
2008/0058,921 IMPROVED ADHESION OF A POLYMERIC COATING OF A DRUG ELUTING STENT 45 2006
2008/0188,836 Medical devices having nanoporous coatings for controlled therapeutic agent delivery 35 2007
2008/0249,615 STENTS WITH CERAMIC DRUG RESERVOIR LAYER AND METHODS OF MAKING AND USING THE SAME 43 2007
2008/0249,600 STENTS WITH DRUG RESERVOIR LAYER AND METHODS OF MAKING AND USING THE SAME 45 2007
2008/0051,881 Medical devices comprising porous layers for the release of therapeutic agents 54 2007
2008/0275,543 Stent 26 2007
2008/0294,236 Endoprosthesis with Select Ceramic and Polymer Coatings 47 2007
2008/0294,246 Endoprosthesis with Select Ceramic Morphology 49 2007
2008/0050,415 Polymeric/ceramic composite materials for use in medical devices 33 2007
2008/0004,691 MEDICAL DEVICES WITH SELECTIVE COATING 46 2007
2009/0018,639 ENDOPROSTHESIS COATING 43 2007
2009/0018,647 ENDOPROSTHESIS COATING 44 2007
2009/0018,644 Boron-Enhanced Shape Memory Endoprostheses 28 2007
2008/0160,259 MEDICAL DEVICES AND METHODS OF MAKING THE SAME 49 2007
2009/0030,504 Medical devices comprising porous inorganic fibers for the release of therapeutic agents 48 2007
2009/0138,077 Articles having ceramic coated surfaces 38 2007
2007/0299,509 MEDICAL DEVICE WITH POROUS SURFACE FOR CONTROLLED DRUG RELEASE AND METHOD OF MAKING THE SAME 43 2007
2008/0071,355 Medical Devices with Drug-Eluting Coating 58 2007
2008/0071,348 Medical Devices 44 2007
2008/0071,349 Medical Devices 49 2007
2008/0071,350 ENDOPROSTHESES 50 2007
2008/0071,358 ENDOPROSTHESES 50 2007
2009/0076,588 Endoprosthesis 48 2007
2008/0071,351 ENDOPROSTHESIS WITH ADJUSTABLE SURFACE FEATURES 47 2007
2008/0071,352 BIOERODIBLE ENDOPROSTHESIS WITH BIOSTABLE INORGANIC LAYERS 46 2007
2008/0071,353 ENDOPROSTHESIS CONTAINING MAGNETIC INDUCTION PARTICLES 45 2007
2008/0086,201 MAGNETIZED BIOERODIBLE ENDOPROSTHESIS 45 2007
2009/0076,595 Medical devices having bioerodable layers for the release of therapeutic agents 36 2007
2008/0097,577 MEDICAL DEVICE HYDROGEN SURFACE TREATMENT BY ELECTROCHEMICAL REDUCTION 47 2007
2008/0147,177 ENDOPROSTHESIS WITH COATINGS 53 2007
2008/0145,400 Ion Bombardment of Medical Devices 44 2007
2009/0118,809 ENDOPROSTHESIS WITH POROUS RESERVOIR AND NON-POLYMER DIFFUSION LAYER 44 2007
2009/0118,812 ENDOPROSTHESIS COATING 44 2007
2009/0118,813 NANO-PATTERNED IMPLANT SURFACES 43 2007
2009/0118,814 ENDOPROSTHESIS COATING 43 2007
2009/0118,815 STENT 44 2007
2009/0118,818 ENDOPROSTHESIS WITH COATING 43 2007
2009/0118,820 DEFORMABLE UNDERLAYER FOR STENT 43 2007
2009/0118,821 ENDOPROSTHESIS WITH POROUS RESERVOIR AND NON-POLYMER DIFFUSION LAYER 45 2007
2009/0118,822 STENT WITH EMBEDDED MATERIAL 45 2007
2009/0118,823 ENDOPROSTHESIS WITH POROUS RESERVOIR 46 2007
2009/0123,521 Medical devices having coatings for controlled therapeutic agent delivery 51 2007
7,749,264 Medical devices and methods of making the same 44 2008
2008/0241,218 Coated medical devices for abluminal drug delivery 44 2008
2008/0243,231 Medical device with a porous surface for delivery of a therapeutic agent 53 2008
2009/0018,642 Methods to improve the stability of celluar adhesive proteins and peptides 24 2008
2008/0255,657 STENT WITH UNCONNECTED STENT SEGMENTS 24 2008
2009/0123,517 MEDICAL DEVICES FOR RELEASING THERAPEUTIC AGENT AND METHODS OF MAKING THE SAME 44 2008
2009/0281,613 Endoprostheses 45 2008
2009/0287,301 Coating for medical implants 44 2008
2009/0306,765 Bioerodible Endoprosthesis 44 2008
2009/0012,603 IMPLANTABLE MEDICAL DEVICES HAVING ADJUSTABLE PORE VOLUME AND METHODS FOR MAKING THE SAME 25 2008
2009/0149,942 ENDOPROSTHESIS HAVING A NON-FOULING SURFACE 44 2008
2009/0028,785 MEDICAL DEVICES WITH COATINGS FOR DELIVERY OF A THERAPEUTIC AGENT 44 2008
2009/0157,172 STENTS WITH POLYMER-FREE COATINGS FOR DELIVERING A THERAPEUTIC AGENT 50 2008
2010/0030,326 Bioerodible Endoprosthesis 43 2008
2009/0157,165 Degradable Endoprosthesis 44 2008
2009/0157,166 Medical Devices Having Porous Component For Controlled Diffusion 28 2008
2010/0008,970 Drug-Eluting Endoprosthesis 46 2008
2009/0192,593 Stent for Delivery a Therapeutic Agent from a Side Surface of a Stent StSrut 36 2009
2009/0202,610 Medical Implants With Polysaccharide Drug Eluting Coatings 44 2009
2009/0259,300 Medical Devices With an Interlocking Coating and Methods of Making the Same 43 2009
2009/0264,975 MEDICAL DEVICES HAVING A COATING OF INORGANIC MATERIAL 28 2009
2009/0319,032 ENDOPROSTHESIS COATING 18 2009
2010/0028,403 MEDICAL DEVICES FOR THERAPEUTIC AGENT DELIVERY 16 2009
2010/0057,197 MEDICAL DEVICES HAVING INORGANIC COATINGS FOR THERAPEUTIC AGENT DELIVERY 49 2009
2010/0070,022 LAYER BY LAYER MANUFACTURING OF A STENT 34 2009
7,922,756 Stent 16 2010
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (73)
5,649,977 Metal reinforced polymer stent 484 1994
5,605,696 Drug loaded polymeric material and method of manufacture 630 1995
6,174,329 Protective coating for a stent with intermediate radiopaque coating 200 1996
5,780,807 Method and apparatus for direct laser cutting of metal stents 355 1997
5,843,172 Porous medicated stent 381 1997
6,240,616 Method of manufacturing a medicated porous metal prosthesis 442 1997
6,287,628 Porous prosthesis and a method of depositing substances into the pores 343 1999
6,251,136 Method of layering a three-coated stent using pharmacological and polymeric agents 333 1999
6,471,721 Vascular stent having increased radiopacity and method for making same 117 1999
6,527,801 Biodegradable drug delivery material for stent 304 2000
6,395,326 Apparatus and method for depositing a coating onto a surface of a prosthesis 465 2000
6,585,765 Implantable device having substances impregnated therein and a method of impregnating the same 262 2000
6,254,632 Implantable medical device having protruding surface structures for drug delivery and cover attachment 470 2000
6,716,444 Barriers for polymer-coated implantable medical devices and methods for making the same 272 2000
6,805,898 Surface features of an implantable medical device 179 2000
6,506,437 Methods of coating an implantable device having depots formed in a surface thereof 351 2000
6,558,733 Method for etching a micropatterned microdepot prosthesis 299 2000
6,663,664 Self-expanding stent with time variable radial force 99 2000
6,758,859 Increased drug-loading and reduced stress drug delivery device 247 2000
6,913,617 Method for creating a textured surface on an implantable medical device 64 2000
6,663,662 Diffusion barrier layer for implantable devices 270 2000
6,790,228 Coating for implantable devices and a method of forming the same 221 2000
2001/0014,717 Coating for implantable devices and a method of forming the same 193 2000
2002/0123,801 Diffusion barrier layer for implantable devices 182 2000
6,635,082 Radiopaque stent 86 2000
6,641,607 Double tube stent 85 2000
2002/0087,123 Adhesion of heparin-containing coatings to blood-contacting surfaces of medical devices 182 2001
6,544,582 Method and apparatus for coating an implantable device 250 2001
6,780,424 Controlled morphologies in polymer drug for release of drugs from polymer films 112 2001
6,673,105 Metal prosthesis coated with expandable ePTFE 74 2001
6,764,505 Variable surface area stent 295 2001
6,712,845 Coating for a stent and a method of forming the same 273 2001
2002/0155,212 Coating for a stent and a method of forming the same 231 2001
6,660,034 Stent for increasing blood flow to ischemic tissues and a method of using the same 259 2001
6,656,506 Microparticle coated medical device 195 2001
2002/0183,581 Radiation or drug delivery source with activity gradient to minimize edge effects 202 2001
6,712,844 MRI compatible stent 73 2001
2003/0004,563 Polymeric stent suitable for imaging by MRI and fluoroscopy 96 2001
6,979,346 System and method for improved stent retention 66 2001
6,753,071 Rate-reducing membrane for release of an agent 268 2001
2003/0104,028 Rate limiting barriers for implantable devices and methods for fabrication thereof 60 2001
6,866,805 Hybrid intravascular stent 90 2001
6,616,765 Apparatus and method for depositing a coating onto a surface of a prosthesis 225 2002
6,723,120 Medicated porous metal prosthesis 209 2002
* 2004/0088,038 Porous metal for drug-loaded stents 81 2002
7,169,178 Stent with drug coating 70 2002
6,908,624 Coating for implantable devices and a method of forming the same 112 2002
6,725,901 Methods of manufacture of fully consolidated or porous medical devices 63 2002
6,896,697 Intravascular stent 73 2002
7,105,018 Drug-eluting stent cover and method of use 69 2002
7,163,715 Spray processing of porous medical devices 90 2002
2004/0224,001 Stent coatings comprising hydrophilic additives 107 2003
6,846,323 Intravascular stent 168 2003
2004/0230,293 INTRAVASCULAR STENT 87 2003
2005/0021,127 Porous glass fused onto stent for drug retention 58 2003
7,056,591 Hydrophobic biologically absorbable coatings for drug delivery devices and methods for fabricating the same 60 2003
7,247,166 Intravascular stent with extendible end rings 27 2003
7,198,675 Stent mandrel fixture and method for selectively coating surfaces of a stent 63 2003
2005/0069,630 Stent mandrel fixture and method for selectively coating surfaces of a stent 78 2003
6,953,560 Barriers for polymer-coated implantable medical devices and methods for making the same 67 2003
7,563,324 System and method for coating an implantable medical device 38 2003
2004/0234,737 Rate-reducing membrane for release of an agent 50 2004
7,229,471 Compositions containing fast-leaching plasticizers for improved performance of medical devices 76 2004
2006/0136,048 Abluminal, multilayer coating constructs for drug-delivery stents 66 2004
7,638,156 Apparatus and method for selectively coating a medical article 26 2005
2007/0148,251 Nanoparticle releasing medical devices 58 2005
2007/0003,589 Coatings for implantable medical devices containing attractants for endothelial cells 58 2006
7,416,558 Drug-eluting stent cover and method of use 45 2006
2007/0032,858 Stent with drug coating 47 2006
2007/0036,905 Method and apparatus for spray processing of porous medical devices 48 2006
2007/0055,349 Stent with drug coating 45 2006
2007/0055,354 Stent with drug coating 43 2006
2007/0059,435 Stent with drug coating 43 2006
 
CORDIS CORPORATION (18)
4,994,071 Bifurcating stent apparatus and method 951 1989
5,163,958 Carbon coated tubular endoprosthesis 405 1991
5,891,108 Drug delivery stent 209 1994
5,882,335 Retrievable drug delivery stent 151 1996
6,273,913 Modified stent useful for delivery of drugs along stent strut 591 1998
5,902,266 Method for delivering a liquid solution to the interior wall surface of a vessel 133 1998
2001/0014,821 BALLOON CATHETER AND STENT DELIVERY SYSTEM HAVING ENHANCED STENT RETENTION 49 1998
6,325,825 Stent with variable wall thickness 147 1999
6,315,708 Stent with self-expanding end sections 90 2000
2002/0051,730 Coated medical devices and sterilization thereof 280 2001
6,776,022 Stent with variable wall thickness 55 2001
6,852,122 Coated endovascular AAA device 82 2003
2005/0137,677 Endovascular graft with differentiable porosity along its length 79 2003
2004/0236,416 Increased biocompatibility of implantable medical devices 61 2004
2006/0200,229 Geometry and material for use in high strength, high flexibility, controlled recoil drug eluting stents 48 2005
2008/0086,199 BIOABSORBABLE DEVICE HAVING COMPOSITE STRUCTURE FOR ACCELERATING DEGRADATION 61 2006
2008/0152,929 POLYMER COATING FOR MEDICAL DEVICES 43 2006
2010/0131,050 ABSORBABLE STENT HAVING A COATING FOR CONTROLLING DEGRADATION OF THE STENT AND MAINTAINING pH NEUTRALITY 42 2008
 
MEDTRONIC VASCULAR, INC. (15)
6,918,929 Drug-polymer coated stent with pegylated styrenic block copolymers 40 2003
7,001,421 Stent with phenoxy primer coating 54 2003
6,979,348 Reflowed drug-polymer coated stent and method thereof 71 2003
2005/0070,996 Drug-eluting stent for controlled drug delivery 76 2003
2006/0149,365 Stent with eccentric coating 39 2003
2004/0111,150 Medical device for delivering a therapeutic substance and method therefor 43 2003
2004/0236,415 Medical devices having drug releasing polymer reservoirs 53 2003
2005/0180,919 Stent with radiopaque and encapsulant coatings 55 2004
2004/0230,176 System for treating a vascular condition that inhibits restenosis at stent ends 73 2004
2004/0236,399 Stent with improved surface adhesion 34 2004
2005/0021,128 Compliant, porous, rolled stent 47 2004
2005/0267,561 System and method for stent deployment and infusion of a therapeutic agent into tissue adjacent to the stent ends 43 2004
7,575,632 Reflowed drug-polymer coated stent and method thereof 13 2007
7,575,593 Implantable device with reservoirs for increased drug loading 34 2007
2008/0243,240 Biodegradable Metal Barrier Layer for a Drug-Eluting Stent 44 2007
 
SCIMED LIFE SYSTEMS, INC. (15)
5,464,450 Biodegradable drug delivery vascular stent 283 1994
5,551,954 Biodegradable drug delivery vascular stent 292 1994
5,500,013 Biodegradable drug delivery vascular stent 336 1995
5,769,883 Biodegradable drug delivery vascular stent 310 1995
6,387,124 Biodegradable drug delivery vascular stent 112 1999
6,395,325 Porous membranes 72 2000
2002/0138,136 Medical device having radio-opacification and barrier layers 77 2001
2002/0065,553 Method for manufacturing a medical device having a coated portion by laser ablation 139 2001
6,652,575 Stent with smooth ends 113 2001
6,869,443 Biodegradable drug delivery vascular stent 132 2002
2004/0086,674 Laser sintering process and devices made therefrom 38 2002
2004/0098,119 Stent with smooth ends 48 2003
2006/0127,442 Use of supercritical fluids to incorporate biologically active agents into nanoporous medical articles 31 2004
2005/0278,016 Stent designed for the delivery of therapeutic substance or other agents 59 2005
2006/0264,138 Composite ePTFE/textile prosthesis 48 2006
 
UNIVERSITY OF VIRGINIA (15)
7,294,409 Medical devices having porous layers and methods for making same 47 2003
2005/0070,989 Medical devices having porous layers and methods for making the same 62 2004
* 2006/0121,080 Medical devices having nanoporous layers and methods for making the same 82 2005
2006/0193,886 Medical devices with nanoporous layers and topcoats 59 2006
2006/0193,887 Medical devices having nanoporous bonding layers 51 2006
2006/0193,888 Methods for using medical devices having nanoporous layers 52 2006
2006/0193,889 Nanoporous layers using thermal dealloying 49 2006
2006/0193,890 Method for loading nanoporous layers with therapeutic agent 64 2006
2006/0276,877 Dealloyed nanoporous stents 59 2006
2006/0276,878 Dealloyed nanoporous stents 52 2006
2006/0276,884 Nanoporous stents with magnesium leaching 51 2006
2006/0276,885 Nanoporous stents with improved radiolucency 52 2006
2006/0271,169 Stent with nanoporous surface 49 2006
2006/0276,879 Medical devices having porous layers and methods for making the same 48 2006
2008/0086,198 NANOPOROUS STENTS WITH ENHANCED CELLULAR ADHESION AND REDUCED NEOINTIMAL FORMATION 23 2007
 
ADVANCED BIO PROSTHETIC SURFACES, LTD. (13)
6,190,404 Intravascular stent and method for manufacturing an intravascular stent 116 1998
6,379,383 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 211 1999
6,537,310 Endoluminal implantable devices and method of making same 143 2000
6,820,676 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 79 2000
6,849,085 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and method of making same 122 2001
6,695,865 Embolic protection device 145 2002
6,733,513 Balloon catheter having metal balloon and method of making same 103 2002
6,936,066 Complaint implantable medical devices and methods of making same 125 2002
2003/0059,640 High strength vacuum deposited nitinol alloy films and method of making same 106 2002
2003/0074,053 Endoluminal implantable stent-grafts 51 2002
6,923,829 Implantable expandable medical devices having regions of differential mechanical properties and methods of making same 44 2002
2004/0181,252 Balloon catheter having metal balloon and method of making same 64 2003
7,235,098 Medical devices having MEMs functionality and methods of making same 47 2004
 
MEDTRONIC, INC. (13)
4,886,062 Intravascular radially expandable stent and method of implant 1316 1987
5,607,463 Intravascular medical device 312 1993
5,443,496 Intravascular radially expandable stent 412 1993
5,545,208 Intralumenal drug eluting prosthesis 309 1993
5,591,224 Bioelastomeric stent 261 1994
5,624,411 Intravascular stent and method 535 1995
5,776,184 Intravasoular stent and method 383 1996
5,824,048 Method for delivering a therapeutic substance to a body lumen 447 1996
6,203,536 Medical device for delivering a therapeutic substance and method therefor 69 1997
6,730,120 Medical device for delivering a therapeutic substance and method therefor 60 2001
2005/0055,080 Modulated stents and methods of making the stents 69 2003
2004/0220,510 Occlusion resistant hydrocephalic shunt 56 2004
2005/0079,199 Porous coatings for drug release from medical devices 65 2004
 
MEDLOGICS DEVICE CORPORATION (12)
2003/0060,873 Metallic structures incorporating bioactive materials and methods for creating the same 82 2002
7,208,172 Metallic composite coating for delivery of therapeutic agents from the surface of implantable devices 44 2003
* 2005/0119,723 Medical device with porous surface containing bioerodable bioactive composites and related methods 66 2003
2005/0106,212 Metallic structures incorporating bioactive materials and methods for creating the same 53 2004
2005/0186,250 Metallic structures incorporating bioactive materials and methods for creating the same 43 2005
2006/0062,820 Metallic structures incorporating bioactive materials and methods for creating the same 49 2005
2006/0051,397 Metallic structures incorporating bioactive materials and methods for creating the same 44 2005
2006/0085,062 Implantable stent with endothelialization factor 45 2005
2006/0115,512 Metallic structures incorporating bioactive materials and methods for creating the same 47 2005
2007/0073,390 Methods and devices for enhanced adhesion between metallic substrates and bioactive material-containing coatings 43 2005
2007/0071,789 Bioactive Material Delivery Systems Comprising Sol-Gel Compositions 26 2006
2007/0181,433 METALLIC COMPOSITE COATINGS FOR DELIVERY OF THERAPEUTIC AGENTS FROM THE SURFACE OF IMPLANTABLE DEVICES 43 2007
 
INNOVATIONAL HOLDINGS LLC (11)
6,241,762 Expandable medical device with ductile hinges 243 1998
2003/0009,214 Medical device with beneficial agent delivery mechanism 81 2002
7,056,338 Therapeutic agent delivery device with controlled therapeutic agent release rates 79 2003
2004/0142,014 Method and apparatus for reducing tissue damage after ischemic injury 66 2003
2004/0143,321 Expandable medical device and method for treating chronic total occlusions with local delivery of an angiogenic factor 69 2003
2004/0202,692 Implantable medical device and method for in situ selective modulation of agent delivery 70 2004
2005/0100,577 Expandable medical device with beneficial agent matrix formed by a multi solvent system 55 2004
2004/0254,635 Expandable medical device for delivery of beneficial agent 59 2004
7,758,636 Expandable medical device with openings for delivery of multiple beneficial agents 24 2005
2006/0222,679 System and method for loading a beneficial agent into a medical device 45 2006
2006/0229,713 Implantable medical device with openings for delivery of beneficial agents with combination release kinetics 47 2006
 
LIFESHIELD SCIENCES LLC (10)
4,657,544 Cardiovascular graft and method of forming same 103 1984
5,693,085 Stent with collagen 501 1995
5,758,562 Process for manufacturing braided composite prosthesis 109 1996
5,741,331 Biostable elastomeric polymers having quaternary carbons 134 1996
6,391,052 Stent with collagen 166 1997
5,968,091 Stents and stent grafts having enhanced hoop strength and methods of making the same 243 1997
6,139,573 Conformal laminate stent device 144 1998
6,514,283 Intraluminal lining 130 2001
6,827,737 EPTFE covering for endovascular prostheses and method of manufacture 66 2001
2004/0158,312 Braided endoluminal device having tapered filaments 5 2003
 
WYETH (10)
7,261,735 Local drug delivery devices and methods for maintaining the drug coatings thereon 59 2001
7,195,640 Coated medical devices for the treatment of vulnerable plaque 70 2002
2004/0002,755 Method and apparatus for treating vulnerable coronary plaques using drug-eluting stents 31 2002
2003/0204,168 Coated vascular devices 142 2002
2004/0167,572 Coated medical devices 332 2003
2005/0136,090 Local vascular delivery of trichostatin a alone or in combination with sirolimus to prevent restenosis following vascular injury 73 2003
2005/0004,663 Heparin barrier coating for controlled drug release 88 2004
2005/0033,417 Coating for controlled release of a therapeutic agent 69 2004
2006/0129,225 Device for the delivery of a cardioprotective agent to ischemic reperfused myocardium 66 2004
2007/0135,908 Absorbable stent comprising coating for controlling degradation and maintaining pH neutrality 49 2005
 
ADVANCED BIO PROSTHETIC SURFACES, LTD. (9)
2001/0001,834 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 60 2000
2001/0032,013 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and method of making same 172 2001
2002/0165,600 Guidewires and thin film catheter-sheaths and method of making same 64 2002
2003/0130,718 Endoluminal implantable stent-grafts 63 2002
2005/0072,544 Endoluminal device exhibiting improved endothelialization and method of manufacture thereof 44 2004
2005/0131,521 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and methods of making same 43 2005
2005/0165,468 Self-supporting laminated films, structural materials and medical devices manufactured therefrom and methods of making same 50 2005
2005/0232,968 Implantable materials having engineered surfaces and method of making same 45 2005
2006/0015,175 Compliant implantable medical devices and methods of making same 44 2005
 
BIOPHAN TECHNOLOGIES, INC. (9)
6,506,972 Magnetically shielded conductor 100 2002
6,673,999 Magnetically shielded assembly 95 2002
6,713,671 Magnetically shielded assembly 101 2002
6,765,144 Magnetic resonance imaging coated assembly 104 2003
6,815,609 Nanomagnetic composition 66 2003
2005/0107,870 Medical device with multiple coating layers 152 2004
2005/0216,075 Materials and devices of enhanced electromagnetic transparency 72 2005
2006/0142,853 Coated substrate assembly 32 2005
2006/0140,867 Coated stent assembly and coating materials 23 2005
 
CID S.P.A. (8)
6,638,302 Stent for angioplasty and associated production process 98 1997
6,565,602 Angioplasty stents 80 2001
6,699,281 Angioplasty stents 117 2002
2003/0195,613 Stent for angioplasty and associated production process 60 2003
7,344,563 Angioplasty stents 54 2004
2005/0209,681 Stent for endoluminal delivery of active principles or agents 49 2005
2007/0151,093 STENT FOR ANGIOPLASTY AND ASSOCIATED PRODUCTION PROCESS 44 2007
2008/0140,186 PROCESS FOR PRODUCING STENTS AND CORRESPONDING STENTS 51 2008
 
MED INSTITUTE, INC. (8)
5,609,629 Coated implantable medical device 680 1995
* 6,096,070 Coated implantable medical device 811 1996
5,824,049 Coated implantable medical device 780 1996
5,873,904 Silver implantable medical device 776 1997
6,530,951 Silver implantable medical device 327 1997
6,299,604 Coated implantable medical device 637 1999
6,918,927 Coated implantable medical device 165 2001
2007/0073,385 Eluting, implantable medical device 68 2006
 
AVANTEC VASCULAR CORPORATION (6)
6,471,980 Intravascular delivery of mycophenolic acid 151 2001
7,077,859 Apparatus and methods for variably controlled substance delivery from implanted prostheses 100 2001
7,083,642 Delivery of therapeutic capable agents 60 2002
2003/0033,007 Methods and devices for delivery of therapeutic capable agents with variable release profile 77 2002
2005/0107,869 Apparatus and methods for controlled substance delivery from implanted prostheses 37 2004
2006/0212,109 Delivery of therapeutic capable agents 34 2006
 
ABBOTT CARDIOVASCULAR SYSTEMS INC. (5)
2003/0083,731 Manufacture of fine-grained material for use in medical devices 56 2001
7,691,461 Hybrid stent and method of making 35 2002
8,029,816 Medical device coated with a coating containing elastin pentapeptide VGVPG 14 2007
2008/0306,584 Implantable medical devices for local and regional treatment 45 2007
7,901,452 Method to fabricate a stent having selected morphology to reduce restenosis 16 2007
 
BOSTON SCIENTIFIC CORPORATION (5)
5,954,706 Drug delivery 140 1995
5,843,089 Stent lining 167 1996
5,928,247 Stent placement device with medication dispenser and method 52 1997
6,364,856 Medical device with sponge coating for controlled drug release 165 1998
5,968,092 Method for making a biodegradable stent 156 1998
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (5)
5,888,591 Chemical vapor deposition of fluorocarbon polymer thin films 79 1996
5,797,898 Microchip drug delivery devices 344 1996
6,013,591 Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production 163 1998
6,045,877 Pyrolytic chemical vapor deposition of silicone films 114 1998
6,156,435 Chemical vapor deposition of fluorocarbon polymer thin films 48 1999
 
SORIN BIOMEDICA CARDIO S.R.L. (5)
2004/0167,612 Process for producing stents and corresponding stents 47 2004
2007/0065,418 Method and device for cellular therapy 45 2006
2007/0219,626 Stents made of biodegradable and non-biodegradable materials 47 2007
2007/0191,928 Angioplasty stents 44 2007
2008/0288,048 STENTS FOR ANGIOPLASTY 43 2007
 
ABPS VENTURE ONE, LTD. (4)
6,458,153 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 393 1999
6,652,578 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 269 2001
2003/0023,300 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 177 2002
2006/0167,543 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 130 2006
 
BIOSENSORS INTERNATIONAL GROUP, LTD. (4)
2003/0225,450 Drug-delivery endovascular stent and method for treating restenosis 42 2003
7,727,275 Drug-delivery endovascular stent and method of forming the same 26 2004
2006/0069,427 Drug-delivery endovascular stent and method for treating restenosis 51 2005
2007/0173,923 Drug reservoir stent 70 2006
 
Biotronik Mess-und Therapiegeraete GmbH & Co. (4)
6,805,709 Stent having discontinuous coating in the form of coating islands 75 2000
6,899,914 Method of applying a marker element to an implant and an implant provided with a marker element 44 2001
6,849,089 Implant with proliferation-inhibiting substance 73 2002
2005/0027,350 Endovascular implant for the injection of an active substance into the media of a blood vessel 47 2003
 
Cardiac Pacemakers, Inc. (4)
6,212,434 Single pass lead system 104 1998
6,361,780 Microporous drug delivery system 61 1998
2005/0131,509 Coatings for implantable electrodes 59 2003
2006/0035,026 Coatings for implantable electrodes 48 2005
 
ISOTECHNIKA INC. (4)
6,342,507 Deuterated rapamycin compounds, method and uses thereof 47 1999
6,503,921 Deuterated rapamycin compounds, methods and uses thereof 53 2001
6,710,053 Deuterated rapamycin compounds, method and uses thereof 44 2002
6,884,429 Medical devices incorporating deuterated rapamycin for controlled delivery thereof 62 2002
 
MEDINOL LTD. (4)
5,449,373 Articulated stent 695 1994
6,315,794 Multilayered metal stent 165 1999
2006/0178,727 Hybrid amorphous metal alloy stent 46 2006
2007/0219,642 Hybrid stent having a fiber or wire backbone 33 2007
 
REGENTS OF THE UNIVERSITY OF MINNESOTA (4)
4,585,652 Electrochemical controlled release drug delivery system 186 1984
5,874,134 Production of nanostructured materials by hypersonic plasma particle deposition 75 1997
6,924,004 Apparatus and method for synthesizing films and coatings by focused particle beam deposition 39 2001
7,247,338 Coating medical devices 43 2002
 
SURMODICS, INC. (4)
2005/0019,371 Controlled release bioactive agent delivery device 73 2004
2005/0244,459 Coating compositions for bioactive agents 70 2005
2005/0196,424 Medical devices and methods for producing the same 62 2005
7,547,445 Crosslinkable macromers 44 2006
 
The United States of America as represented by the Secretary of the Navy (4)
5,242,706 Laser-deposited biocompatible films and methods and apparatuses for producing same 63 1991
5,380,298 Medical device with infection preventing feature 74 1993
6,025,036 Method of producing a film coating by matrix assisted pulsed laser deposition 65 1997
6,660,343 Fabrication of conductive/non-conductive nanocomposites by laser evaporation 17 2001
 
ABBOTT LABORATORIES (3)
7,208,190 Method of loading beneficial agent to a prosthesis by fluid-jet application 43 2003
2007/0191,943 Integration Of Therapeutic Agent Into A Bioerodible Medical Device 51 2006
2008/0057,103 METHODS OF USING MEDICAL DEVICES FOR CONTROLLED DRUG RELEASE 28 2007
 
ANGIOTECH PHARMACEUTICALS, INC. (3)
6,106,473 Echogenic coatings 186 1997
2002/0165,265 ANTI-ANGIOGENIC COMPOSITIONS AND METHODS OF USE 67 1997
6,846,841 Anti-angiogenic compositions and methods of use 61 2002
 
DEPUY PRODUCTS, INC. (3)
6,569,489 Bioactive ceramic coating and method 97 2000
6,736,849 Surface-mineralized spinal implants 48 2002
7,368,065 Implants with textured surface and methods for producing the same 53 2005
 
ICON INTERVENTIONAL SYSTEMS, INC. (3)
6,206,916 Coated intraluminal graft 152 1999
2002/0099,438 Irradiated stent coating 83 2001
2007/0032,864 Thrombosis inhibiting graft 51 2005
 
PRESIDENT AND FELLOWS OF HARVARD COLLEGE (3)
5,951,881 Fabrication of small-scale cylindrical articles 144 1996
6,776,094 Kit For Microcontact Printing 185 1998
2004/0178,523 Molded waveguides 36 2003
 
TERUMO KABUSHIKI KAISHA (3)
6,833,004 Stent 83 2002
2003/0181,975 Stent 55 2003
2003/0216,806 Stent 23 2003
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (3)
7,048,939 Methods for the inhibition of neointima formation 48 2002
7,056,339 Drug delivery platform 50 2002
7,981,441 Drug delivery systems using mesoporous oxide films 13 2004
 
UNIVERSITY OF CONNECTICUT (3)
2005/0010,275 Implantable medical devices 98 2003
2005/0216,074 Implantable medical devices 100 2004
2005/0251,249 Endoprostheses 58 2005
 
WARSAW ORTHOPEDIC, INC. (3)
6,323,146 Synthetic biomaterial compound of calcium phosphate phases particularly adapted for supporting bone cell activity 109 1998
2002/0138,146 Anterior expandable spinal fusion cage system 8 2002
2006/0229,715 Implants incorporating nanotubes and methods for producing the same 42 2005
 
ABBOTT LABORATORIES VASCULAR ENTERPRISES LIMITED (2)
2004/0133,270 Drug eluting stent and methods of manufacture 73 2003
2006/0155,361 Stent with rough surface and its manufacture 47 2003
 
ALCOVE SURFACES GMBH (2)
6,709,379 Implant with cavities containing therapeutic agents 225 2001
6,740,077 Implant with permeable element 61 2001
 
ALZA CORPORATION (2)
4,309,996 System with microporous releasing diffusor 121 1980
6,071,305 Directional drug delivery stent and method of use 418 1997
 
AMS MEDINVENT S.A. (2)
4,655,771 Prosthesis comprising an expansible or contractile tubular body 1371 1983
5,061,275 Self-expanding prosthesis 648 1989
 
ANGIOTECH INTERNATIONAL AG (2)
2004/0219,214 Tissue reactive compounds and compositions and uses thereof 70 2003
2005/0165,467 Intravascular devices and fibrosis-inducing agents 31 2004
 
ATRIUM MEDICAL CORPORATION (2)
6,955,661 Expandable fluoropolymer device for delivery of therapeutic agents and method of making 70 1999
2003/0153,901 Drug delivery panel 57 2002
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (2)
2003/0050,687 Biocompatible stents and method of deployment 74 2001
7,238,199 Method and apparatus for stent deployment with enhanced delivery of bioactive agents 48 2002
 
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (2)
2003/0083,614 Controlled release endoprosthetic device 47 2002
2005/0192,664 Controlled release endoprosthetic device 44 2005
 
CaP Biotechnology, Inc. (2)
6,210,715 Calcium phosphate microcarriers and microspheres 128 2000
6,358,532 Calcium phosphate microcarriers and microspheres 43 2001
 
COOK INCORPORATED (2)
4,800,882 Endovascular stent and delivery system 1279 1987
2005/0159,804 Multiple stitches for attaching stent to graft 65 2005
 
COOK MEDICAL TECHNOLOGIES LLC (2)
2003/0028,243 Coated implantable medical device 269 2002
2005/0278,021 Coated medical device 78 2005
 
CORVITA CORPORATION (2)
4,738,740 Method of forming implantable vascular grafts 134 1985
4,743,252 Composite grafts 246 1986
 
DIMICRON, INC. (2)
6,488,715 Diamond-surfaced cup for use in a prosthetic joint 89 2000
6,514,289 Diamond articulation surface for use in a prosthetic joint 39 2000
 
ELECTROFORMED STENTS, INC. (2)
6,904,658 Process for forming a porous drug delivery layer 62 2003
2004/0237,282 Process for forming a porous drug delivery layer 47 2003
 
Exxon Research and Engineering Company (2)
4,407,695 Natural lithographic fabrication of microstructures over large areas 121 1982
5,852,088 Nanoporous ceramics with catalytic functionality 45 1995
 
FLAME-SPRAY INDUSTRIES, INC. (2)
6,139,913 Kinetic spray coating method and apparatus 117 1999
6,283,386 Kinetic spray coating apparatus 87 2000
 
GENESIS MICROCHIP INC. (2)
6,973,718 Methods for conformal coating and sealing microchip reservoir devices 78 2002
2006/0093,646 Orthopedic and dental implant devices providing controlled drug delivery 69 2005
 
Harbor Medical Devices, Inc. (2)
5,447,724 Medical device polymer 433 1993
5,569,463 Medical device polymer 339 1995
 
ICON MEDICAL CORP. (2)
2007/0123,973 Biodegradable device 50 2006
2010/0042,206 BIOABSORBABLE COATINGS FOR MEDICAL DEVICES 54 2009
 
INFRAMAT CORPORATION (2)
2008/0069,854 MEDICAL DEVICES AND METHODS OF MAKING AND USING 51 2007
2008/0124,373 LUMEN - SUPPORTING DEVICES AND METHODS OF MAKING AND USING 46 2007
 
INTERNATIONAL BUSINESS MACHINES CORPORATION (2)
5,693,928 Method for producing a diffusion barrier and polymeric article having a diffusion barrier 48 1996
6,962,822 Discrete nano-textured structures in biomolecular arrays, and method of use 45 2002
 
KINIK COMPANY (2)
6,830,598 Molten braze coated superabrasive particles and associated methods 27 2002
7,261,752 Molten braze-coated superabrasive particles and associated methods 27 2003
 
KIPS BAY MEDICAL, INC. (2)
2005/0055,085 Implantable medical devices having recesses 52 2003
2006/0184,235 Implantable medical devices having recesses 44 2006
 
LUCENT TECHNOLOGIES INC. (2)
5,681,196 Spaced-gate emission device and method for making same 39 1995
6,504,292 Field emitting device comprising metallized nanostructures and method for making the same 119 1999
 
MEDTRONIC AVE, INC. (2)
5,290,585 Lubricious hydrogel coatings 129 1992
6,206,915 Drug storing and metering stent 156 1998
 
NANOSYS, INC. (2)
2005/0038,498 Medical device applications of nanostructured surfaces 163 2004
2005/0221,072 Medical device applications of nanostructured surfaces 116 2005
 
NICAST LTD. (2)
2004/0030,377 Medicated polymer-coated stent assembly 62 2003
7,244,272 Vascular prosthesis and method for production thereof 51 2005
 
Norman Noble, Inc., (2)
6,709,451 Channeled vascular stent apparatus and method 71 2000
2004/0181,275 Channeled vascular stent apparatus and method 44 2004
 
NOVOSTENT CORPORATION (2)
2004/0122,504 Vascular prosthesis and methods of use 52 2003
2004/0158,308 Delivery catheter for ribbon-type prosthesis and methods of use 44 2004
 
ORBUSNEICH MEDICAL, INC. (2)
2004/0039,441 Drug eluting implantable medical device 90 2003
2007/0129,789 Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device 45 2006
 
PFIZER INC. (2)
2005/0137,679 Modified stent useful for delivery of drugs along stent strut 46 2004
2005/0137,684 Stent with therapeutically active drug coated thereon 46 2004
 
PRECISION VASCULAR SYSTEMS, INC. (2)
6,214,042 Micro-machined stent for vessels, body ducts and the like 109 1998
6,063,101 Stent apparatus and method 202 1998
 
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (2)
5,587,507 Synthesis of tyrosine derived diphenol monomers 106 1995
6,475,477 Radio-opaque polymer biomaterials 99 2000
 
SPECTRA-PHYSICS, INC. (2)
2004/0000,540 Laser texturing of surfaces for biomedical implants 50 2003
2005/0211,680 Systems and methods for laser texturing of surfaces of a substrate 78 2005
 
STENT TECH, INC. (2)
5,858,556 Multilayer composite tubular structure and method of making 270 1997
2002/0133,222 Expandable stent having a plurality of interconnected expansion modules 50 2002
 
SYNTHEON, LLC (2)
6,527,938 Method for microporous surface modification of implantable metallic medical articles 94 2001
2003/0108,659 Implantable metallic medical articles having microporous surface structure 59 2003
 
The Boeing Company (2)
5,968,640 Conductive, thermally stable oligomers 29 1985
7,837,726 Visible endoprosthesis 69 2006
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (2)
2004/0026,811 Tissue engineering scaffolds 27 2002
2010/0130,346 METHOD OF PRESSURELESS SINTERING PRODUCTION OF DENSIFIED CERAMIC COMPOSITES 13 2009
 
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (2)
5,830,480 Stabilization of sol-gel derived silica-based glass 42 1996
2005/0019,265 Polymersomes incorporating highly emissive probes 51 2004
 
THORATEC CORPORATION (2)
6,327,504 Transcutaneous energy transfer with circuitry arranged to avoid overheating 66 2000
6,752,826 Layered stent-graft and methods of making the same 193 2001
 
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (2)
2002/0169,493 Anti-thrombogenic coatings for biomedical devices 46 2001
2004/0052,861 Sol-gel derived bioactive glass polymer composite 19 2003
 
WORLD HEART CORPORATION (2)
4,665,896 Power supply for body implant and method of use 141 1985
6,270,831 Method and apparatus for providing a conductive, amorphous non-stick coating 163 1998
 
XTENT, INC. (2)
2004/0243,217 Expandable stent 87 2004
2005/0228,477 Topographic coatings and coating methods for medical devices 81 2005
 
3M INNOVATIVE PROPERTIES COMPANY (1)
2002/0095,871 Method of making ceramic aggregate particles 37 2001
 
ABPS Venture One, Ltd. (1)
7,018,408 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 109 2003
 
Advanced Bio Prosthetic Surface, Ltd., a wholly owned subsidiary of Palmaz Scientific, Inc. (1)
7,195,641 Valvular prostheses having metal or pseudometallic construction and methods of manufacture 181 2002
 
ADVANCED LASER APPLICATIONS HOLDING S.A. (1)
2004/0006,382 Intraluminar perforated radially expandable drug delivery prosthesis 68 2003
 
AIR PRODUCTS AND CHEMICALS, INC. (1)
2002/0142,579 ORGANOSILICON PRECURSORS FOR INTERLAYER DIELECTRIC FILMS WITH LOW DIELECTRIC CONSTANTS 49 2001
 
Aita, Carolyn (1)
6,869,701 Self-repairing ceramic coatings 53 1999
 
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (1)
5,405,367 Structure and method of manufacture of an implantable microstimulator 334 1993
 
ALLIEDSIGNAL INC. (1)
6,022,812 Vapor deposition routes to nanoporous silica 48 1998
 
ANELVA CORPORATION (1)
6,878,249 High frequency sputtering device 44 2001
 
APPLIED MATERIALS, INC. (1)
6,367,412 Porous ceramic liner for a plasma source 57 2000
 
APPLIED MEDICAL RESOURCES CORPORATION (1)
2005/0113,936 Surface treatments and modifications using nanostructure materials 85 2004
 
Applied Microstructures, Inc. (1)
2006/0088,666 Controlled vapor deposition of biocompatible coatings over surface-treated substrates 55 2005
 
AQUAMARIJN HOLDING B.V. (1)
2004/0028,875 Method of making a product with a micro or nano sized structure and product 155 2003
 
ASTELLAS PHARMA INC. (1)
2004/0117,008 Medical implants containing FK506 (tacrolimus), methods of making and methods of use thereof 79 2003
 
AZMED, LTD. (1)
2005/0251,245 Methods and apparatus with porous materials 50 2004
 
B. BRAUN-SSC AG (1)
4,902,290 Process for the preparation of a vessel prosthesis impregnated with crosslinked gelatin 82 1988
 
BADARI NAYANAN NAGARADA GADDE (1)
2004/0117,005 Stent with drug-delivery system 48 2004
 
BASF CORPORATION (1)
5,686,499 Polyurethane foams containing high levels of silicone-containing surfactant polymer to improve flame retardance and aged K-factors 24 1995
 
BAYER MATERIALSCIENCE AG (1)
6,599,558 Treating metal surfaces to enhance bio-compatibility and/or physical characteristics 59 1999
 
BEST MEDICAL INTERNATIONAL, INC. (1)
6,709,397 Scanning probe 57 2002
 
BIOCER ENTWICKLUNGS GMBH (1)
2009/0317,766 Structured coatings for implants and process for the preparation thereof 31 2007
 
BIOSENSORS INTERNATIONAL USA (1)
2003/0088,307 Potent coatings for stents 148 2002
 
BIOTRONIK AG (1)
6,287,332 Implantable, bioresorbable vessel wall support, in particular coronary stent 241 1999
 
BIOTRONIK IV PATENT AG (1)
2006/0052,864 Endoprosthesis comprising a magnesium alloy 57 2005
 
BIOTRONIK VI PATENT AG (1)
2006/0052,863 Endoprosthesis comprising a magnesium alloy 53 2005
 
BLERSCH, JUERGEN, DR. (1)
2005/0079,201 Implants with functionalized carbon surfaces 45 2004
 
BLUE MEDICAL DEVICES B.V. (1)
2008/0050,413 Medical stent provided with a combination of melatonin and paclitaxel 46 2006
 
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (1)
7,311,727 Encased stent 55 2004
 
BODYCOTE ORTECH INC. (1)
4,475,972 Implantable material 152 1982
 
BOSTON SCIENTIFIC LIMITED (1)
6,335,029 Polymeric coatings for controlled delivery of active agents 428 1998
 
BRIDGE BLOOD TECHNOLOGIES LLC, NEW YORK LIMITED LIABILITY COMPANY (1)
5,322,520 Iontophoretic structure for medical devices 184 1992
 
Calcitec, Inc. (1)
2007/0213,827 Hardened calcium phosphate cement bone implants 27 2006
 
CAMBRIDGE POLYMER GROUP, INC. (1)
2004/0092,653 Systems and methods for controlling and forming polymer gels 54 2003
 
CAPHCO, INC. (1)
5,788,687 Compositions and devices for controlled release of active ingredients 79 1995
 
CASE WESTERN RESERVE UNIVERSITY (1)
2003/0118,649 Drug delivery devices and methods 67 2002
 
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (1)
6,468,304 Implantable device covered with polymer capable of releasing biologically active substances 58 2000
 
CERNOFINA, LLC (1)
7,087,661 Safe and effective biofilm inhibitory compounds and health-related uses thereof 32 1999
 
CINVENTION AG (1)
2006/0171,990 Drug delivery materials made by sol/gel technology 20 2006
 
COCHLEAR LIMITED (1)
5,279,292 Charging system for implantable hearing aids and tinnitus maskers 223 1992
 
CODMAN & SHURTLEFF, INC. (1)
6,955,685 Expandable stent with radiopaque markers and stent delivery system 95 2003
 
COMMISSARIAT A L'ENERGIE ATOMIQUE (1)
2006/0141,156 Surface-coating method 58 2004
 
CONOR MEDSYSTEMS, INC. (1)
7,208,011 Implantable medical device with drug filled holes 74 2002
 
CONTROL DELIVERY SYSTEMS, INC. (1)
2003/0158,598 System for sustained-release delivery of anti-inflammatory agents from a coated medical device 86 2003
 
CORNELL UNIVERSITY (1)
5,219,611 Preparing densified low porosity titania sol gel forms 39 1991
 
CV THERAPEUTICS, INC. (1)
7,160,592 Polymer coating for medical devices 61 2003
 
DAI NIPPON PRINTING CO., LTD. (1)
5,679,440 Optical card 51 1995
 
DEBIOTECH S.A. (1)
2009/0177,273 ANISOTROPIC NANOPOROUS COATINGS FOR MEDICAL IMPLANTS 45 2007
 
DELCATH SYSTEMS, INC. (1)
5,817,046 Apparatus and method for isolated pelvic perfusion 89 1997
 
Delpor, Inc. (1)
2005/0118,229 Implantable drug delivery device for sustained release of therapeutic agent 20 2004
 
DEPUY INC. (1)
5,368,881 Prosthesis with highly convoluted surface 51 1993
 
DEPUY ORTHOPAEDICS, INC. (1)
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* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (1)
* 8,663,317 Intraluminar perforated radially expandable drug delivery prosthesis and a method for the production thereof 0 2012
* Cited By Examiner

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