US Patent No: 8,188,072
Number of patents in Portfolio can not be more than 2000
Benzodiazepinone compounds useful in the treatment of skin conditions
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May 29, 2012
Issued date -
Nov 6, 2008
filing date -
12/266,239
serial no -
In Force
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Abstract
The present invention provides a family of benzodiazepinone compounds and pharmaceutical compositions thereof. The present invention also provides methods of treating certain skin conditions, e.g., atopic dermatitis, rosacea, or psoriasis, by administering a benzodiazepinone and methods of reducing the proliferation of keratinocyte cells by exposing such cells to a benzodiazepinone.
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First Claim
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 6,080,588 Therapeutic methods for benzodiazepine derivatives | 18 | 1997 | |
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| 7,572,788 Compositions and methods relating to novel compounds and targets thereof | 8 | 2003 | |
| 2004/0176,358 Compositions and methods relating to novel compounds and targets thereof | 14 | 2003 | |
| 7,276,348 Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof | 13 | 2004 | |
| 2006/0025,388 Compositions and methods relating to novel compounds and targets thereof | 15 | 2004 | |
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| 2005/0272,723 Methods and compositions for treating diseases and conditions associated with mitochondrial function | 14 | 2005 | |
| 2006/0052,369 Compositions and methods relating to novel compounds and targets thereof | 14 | 2005 | |
| 7,638,624 Compositions and methods relating to novel benzodiazepine compounds and derivatives | 8 | 2006 | |
| 2006/0166,975 Compositions and methods relating to novel compounds and targets thereof | 9 | 2006 | |
| 2007/0043,033 Unsolvated benzodiazepine compositions and methods | 10 | 2006 | |
| 2007/0036,854 Therapeutic applications of pro-apoptotic benzodiazepines | 9 | 2006 | |
| 2007/0105,844 Therapeutic compositions and methods | 9 | 2006 | |
| 2007/0111,994 Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties | 9 | 2006 | |
| 2007/0135,418 Compositions and methods relating to novel compounds and targets thereof | 12 | 2006 | |
| 2008/0064,686 Novel soluble 1,4 benzodiazepine compounds and stable salts thereof | 9 | 2007 | |
| 2007/0299,059 Compostions and methods relating to novel compounds and targets thereof | 12 | 2007 | |
| 7,851,465 Compositions and methods relating to novel compounds and targets thereof | 7 | 2008 | |
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| 5,147,872 Treatment of immunologically based disorders, specifically psoriasis | 8 | 1990 | |
| 5,444,092 Method and composition for treating psoriasis | 22 | 1994 | |
| 6,277,844 Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis | 21 | 1999 | |
| 6,524,623 Therapeutic compositions and methods of use thereof | 15 | 2000 | |
| 2002/0048,566 Modulation of cellular apoptosis and methods for treating cancer | 28 | 2001 | |
| 2004/0087,489 Compositions and methods for the treatment of mycobacterial infections | 14 | 2003 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
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| 3.5 Year Payment | $1600.00 | $800.00 | $400.00 | Nov 29, 2015 |
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Nov 29, 2019 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Nov 29, 2023 |
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge - 3.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |