Peptide homing to brain tumors
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United States of America Patent
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May 29, 2012
Grant Date -
Jun 2, 2011
app pub date -
May 8, 2009
filing date -
May 9, 2008
priority date (Note) -
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Abstract
The present invention relates to a peptide, which specifically homes to the intracranial, early stage astrocytoma model that grows as islets and harbors co-opted tumor vessels in the brain. The peptide finds its use in targeted delivery of therapeutic substances to invasive brain cancer or metastatic brain lesions as such and in combination with conventional therapies, such as surgery and radiation, and anti-angiogenic therapies, and as a tool in diagnosis of, e.g., invasive brain cancer or metastatic brain lesions.
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