Implantable medical devices with anti-microbial and biodegradable matrices

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United States of America Patent

PATENT NO 8192481
APP PUB NO 20100324667A1
SERIAL NO

12869870

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Abstract

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A composite vascular graft is provided, which incorporates bioactive agents that can be controllably delivered to the implantation site to deliver therapeutic materials and/or to reduce infection of the implant. The vascular graft of the present invention includes a luminal layer of ePTFE; and a biodegradable polymer layer including a bioactive agent, such as an antimicrobial agent. The biodegradable polymer layer is posited on the external surface of the luminal ePTFE layer. The graft also includes a fabric layer, which is posited on the external surface of the biodegradable layer. The graft is particularly useful as an arterial-venous graft for hemodialysis procedures.

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Patent Owner(s)

  • LIFESHIELD SCIENCES LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
King, Tamarah L Haskell, US 2 147

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