Matrix made of polyester polymers entangled with hyaluronic polymers useful for supporting tissue repair
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United States of America Patent
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Jun 5, 2012
Grant Date -
Jan 12, 2006
app pub date -
Jul 11, 2005
filing date -
Jul 12, 2004
priority date (Note) -
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Abstract
The present application discloses matrix compositions to support the repair of tissue defects such as an osteochondral injury. A matrix described herein comprises a polyester polymer entangled with a polysaccharide polymer. Also disclosed are methods of preparing a matrix, and methods of using a matrix in the repair of tissue. In certain configurations, a matrix can comprise a polyester cross-linked with a polysaccharide, which can be an oxidized polysaccharide. In some configurations, a matrix can further comprise one or more additional components, such as a growth factor.
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