Methods for quantification of microRNAs and small interfering RNAs
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United States of America Patent
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Jun 5, 2012
Grant Date -
Dec 8, 2005
app pub date -
Apr 7, 2005
filing date -
Apr 7, 2004
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Abstract
The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.
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