Excitatory glycine receptors and methods
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United States of America Patent
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Jun 5, 2012
Grant Date -
Feb 24, 2011
app pub date -
Jul 23, 2010
filing date -
Aug 20, 2001
priority date (Note) -
Expired
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Abstract
The invention provides isolated N-methyl-D-aspartate type 3B (NR3B) polypeptides, functional fragments and peptides, encoding nucleic acid molecules and polynucleotides, and specific antibodies. Also provided are excitatory glycine receptors, containing either NR3B or NR3A polypeptides. Further provided are methods for detecting excitatory glycine receptor ligands, agonists and antagonists. The invention also provides related diagnostic and therapeutic methods.
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