US Patent No: 8,206,701

Number of patents in Portfolio can not be more than 2000

Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells

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ALSO PUBLISHED AS: 20050175596
ATTORNEY / AGENT: (SPONSORED)
 

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Abstract

The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
HELMHOLTZ ZENTRUM MUNCHEN DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH)NEUHERBERG17

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
SCHENDEL, DOLORES MUNCHEN, DE 10 6
Wank, Rudolf Munchen, DE 7 4

Cited Art

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LEE BIOMOLECULAR RESEARCH LABORATORIES, INC. (1)
4,568,542 Vaccine compositions 9 1981
 
MEDICAL UNIVERSITY OF SOUTH CAROLINA (1)
6,063,375 Semiallogeneic cell hybrids and related methods for treating cancer 3 1996
 
NEXELL THERAPEUTICS INC. (1)
6,458,585 Cytokine-free culture of dendritic cells 8 1997
 
RIBI IMMUNOCHEM RESEARCH, INC. (1)
4,877,611 Vaccine containing tumor antigens and adjuvants 58 1987
 
THOMAS JEFFERSON UNIVERSITY (1)
5,290,551 Treatment of melanoma with a vaccine comprising irradiated autologous melanoma tumor cells conjugated to a hapten 20 1992
 
UNITED STATES OF AMERICA (1)
5,156,841 Anti-tumor vaccine 8 1988
 
UNIVERSITY OF PITTSBURGH (1)
6,077,519 Methods for isolation and use of T cell epitopes eluted from viable cells in vaccines for treating cancer patients 14 1997
 
YEDA RESEARCH AND DEVELOPMENT CO. LTD. (1)
5,582,831 Anti-tumor vaccines 10 1994
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (2)
2002/0123,479 Immunostimulation mediated by gene-modified dendritic cells 1 2001
2002/0168,351 Fusion cells and cytokine compositions for treatment of disease 2 2001

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