US Patent No: 8,206,706
Number of patents in Portfolio can not be more than 2000
Method for enhancing or inhibiting insulin-like growth factor-I
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Jun 26, 2012
Issued date -
Feb 18, 2009
filing date -
12/388,045
serial no -
In Force
status
Importance
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Abstract
The present invention provides αVβ3 integrin cysteine loop domain agonists and antagonists (including peptide agonists and antagonists and analogs thereof), along with methods of using the same.
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First Claim
Related Publications
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
|---|---|---|---|
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| 6,531,580 Anti-.alpha.v.beta.3 recombinant human antibodies and nucleic acids encoding same | 11 | 1999 | |
| 7,371,382 Methods of inhibiting .alpha..sub.v.beta..sub.3-mediated binding with .alpha..sub.v.beta..sub.3-specific antibodies | 4 | 2002 | |
| 7,422,744 Methods of treating cancer with alphavbeta3-specific antibodies | 4 | 2003 | |
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| 6,590,079 Anti-.alpha.v.beta.3 recombinant human antibodies, nucleic acids encoding same | 7 | 1997 | |
| 6,596,850 Anti-.alpha.v3.beta.3 recombinant human antibodies, nucleic acids encoding same | 7 | 1998 | |
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| 5,753,230 Methods and compositions useful for inhibition of angiogenesis | 67 | 1994 | |
| 7,354,586 Methods of treating arthritis and diabetic retinopathy with .alpha..sub.v.beta..sub.3-specific antibodies | 4 | 2004 | |
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| 7,723,483 Method for enhancing or inhibiting insulin-like growth factor-I | 2 | 2005 | |
| 2009/0280,127 MONOCLONAL ANTIBODIES FOR ENHANCING OR INHIBITING INSULIN-LIKE GROWTH FACTOR-I | 1 | 2009 | |
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| 5,578,704 Antibody to osteoclast alphavbeta3 ntegrin | 24 | 1994 | |
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| 6,887,473 Inhibition of angiogenesis in disease states with an anti-αvβ3 monoclonal antibody | 8 | 1998 | |
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| 5,336,618 Fibrinogen blocking monoclonal antibody | 8 | 1988 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 3.5 Year Payment | $1600.00 | $800.00 | $400.00 | Dec 26, 2015 |
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Dec 26, 2019 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Dec 26, 2023 |
| Fee | Large entity fee | small entity fee | micro entity fee |
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| Surcharge - 3.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |