Evolving new molecular function

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8206914
APP PUB NO 20110190141A1
SERIAL NO

12834072

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The power of Nature and the flexibility of organic synthesis are combined in nucleic acid-templated synthesis. The present invention provides a variety of template architectures for performing nucleic acid-templated synthesis, methods for increasing the selectivity of nucleic acid-templated reactions, methods for performing stereoselective nucleic acid-templated reactions, methods of selecting for reaction products resulting from nucleic acid-templated synthesis, and methods of identifying new chemical reactions based on nucleic acid-templated synthesis.

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Patent Owner(s)

Patent OwnerAddress
PRESIDENT AND FELLOWS OF HARVARD COLLEGE17 QUINCY STREET CAMBRIDGE MA 02138

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Calderone, Christopher T Boston, US 5 245
Doyon, Jeffrey B Allston, US 2 54
Gartner, Zev J Santa Cruz, US 9 391
Kanan, Matthew W Cambridge, US 21 677
Li, Xiaoyu Cambridge, US 88 634
Liu, David R Lexington, US 236 9909
Rosenbaum, Daniel M Burlingame, US 6 91
Snyder, Thomas M Cambridge, US 50 656

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