Nucleic acids and corresponding proteins entitled 158P3D2 useful in treatment and detection of cancer
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United States of America Patent
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Jul 3, 2012
Grant Date -
Apr 7, 2011
app pub date -
Oct 6, 2010
filing date -
Apr 10, 2001
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Expired
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Abstract
A novel gene 158P3D2 and its encoded protein, and variants thereof, are described wherein 158P3D2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 158P3D2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 158P3D2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 158P3D2 can be used in active or passive immunization.
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