Ultra-sensitive detection of molecules on single molecule arrays
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United States of America Patent
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Jul 17, 2012
Grant Date -
Mar 25, 2010
app pub date -
Sep 23, 2008
filing date -
Sep 23, 2008
priority date (Note) -
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Abstract
The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may comprise immobilizing a plurality of analyte molecules or particles to form a plurality of complexes, releasing at least a portion of some of the plurality of complexes, determining at least a portion of the plurality of complexes released, and determining a measure of the concentration of the analyte molecules or particles in a fluid sample.
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