Stable formulations of thiadiazole derivative
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United States of America Patent
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Jul 17, 2012
Grant Date -
Jan 13, 2011
app pub date -
Jul 7, 2008
filing date -
Jul 12, 2007
priority date (Note) -
Expired
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Abstract
The present invention provides formulation parameters and manufacturing conditions for stable pharmaceutical compositions comprising N-{4-(2,2-dimethyl-propionyl)-(5R)-5-[(2-ethylamino-ethanesulfonylamino)-methyl]-5-phenyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl}-2,2-dimethyl-propionamide that minimize undesirable chiral conversion to the less active S enantiomeric form.
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