ADH promoter and use thereof to direct expression of proteins
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United States of America Patent
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Jul 17, 2012
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app pub date -
Oct 10, 2007
filing date -
Oct 10, 2006
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Abstract
Novel promoters which are derived from P. pastoris pastoris which are inducible or repressible under specific growth conditions are provided. These promoters are useful for regulating the expression of a desired structural gene, e.g., a mammalian polypeptide. Particularly preferred is the use of these novel promoters to regulate gene expression in polyploidal yeast such as diploidal P. pastoris produced by mating or spheroplast fusion.
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