US Patent No: 8,226,942
Number of patents in Portfolio can not be more than 2000
PDGF fusion proteins incorporated into fibrin foams
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Jul 24, 2012
Issued date -
Dec 23, 2008
filing date -
12/342,420
serial no -
In Force
status
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Abstract
Compositions for wound healing, use of the compositions, and kits and methods of using thereof are described herein. In a preferred aspect, the compositions are suitable for use in a method for forming a fibrin matrix or foam that can be applied or injected at the site of need. In another preferred aspect, the compositions are also suitable for use in methods for forming enhanced controlled delivery fibrin matrices that can be administered as gels or foams.
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First Claim
Related Publications
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 6,894,022 Growth factor modified protein matrices for tissue engineering | 4 | 2000 | |
| 6,468,731 Enzyme-mediated modification of fibrin for tissue engineering: incorporation of proteins | 5 | 2000 | |
| 6,960,452 Enzyme-mediated modification of fibrin for tissue engineering: incorporation of proteins | 3 | 2001 | |
| 6,723,344 Controlled release of non heparin-binding growth factors from heparin-containing matrices | 10 | 2001 | |
| 7,241,730 Enzyme-mediated modification of fibrin for tissue engineering: fibrin formulations with peptides | 3 | 2002 | |
| 2003/0187,232 Growth factor modified protein matrices for tissue engineering | 13 | 2002 | |
| 7,601,685 Growth factor modified protein matrices for tissue engineering | 1 | 2002 | |
| 7,247,609 Growth factor modified protein matrices for tissue engineering | 4 | 2002 | |
| 2007/0179,093 GROWTH FACTOR MODIFIED PROTEIN MATRICES FOR TISSUE ENGINEERING | 1 | 2007 | |
| 2007/0202,178 DRUG DELIVERY MATRICES TO ENHANCE WOUND HEALING | 1 | 2007 | |
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| 6,197,325 Supplemented and unsupplemented tissue sealants, methods of their production and use | 104 | 1995 | |
| 7,189,410 Supplemented and unsupplemented tissue sealants, methods of their production and use | 4 | 1995 | |
| 7,196,054 Methods for treating wound tissue and forming a supplemented fibrin matrix | 5 | 1995 | |
| 7,229,959 Supplemented fibrin matrix delivery systems | 1 | 1995 | |
| RE39192 Supplemented and unsupplemented tissue sealants, methods of their production and use | 2 | 2003 | |
| RE39298 Supplemented and unsupplemented tissue sealants, methods of their production and use | 2 | 2003 | |
| RE39321 Supplemented and unsupplemented tissue sealants, methods of their production and use | 25 | 2003 | |
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| 6,331,422 Enzyme-mediated modification of fibrin for tissue engineering | 20 | 1998 | |
| 6,607,740 Enzyme-mediated modification of fivrin for tissue engineering | 1 | 2000 | |
| 2002/0168,718 Enzyme-mediated modification of fibrin for tissue engineering | 2 | 2001 | |
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| 5,504,001 Hybrid plasminogen activator | 11 | 1994 | |
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| 5,529,986 Conjugate, its preparation and use and a substrate prepared with the conjugate | 22 | 1994 | |
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| 6,150,328 BMP products | 28 | 1991 | |
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| 5,840,837 Analogs of parathyroid hormone and parathyroid hormone relate peptide synthesis and use for the treatment of osteoporosis | 20 | 1995 | |
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| 5,641,670 Protein production and protein delivery | 92 | 1994 | |
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| 5,561,982 Method for energy separation and utilization in a vortex tube which operates with pressure not exceeding atmospheric pressure | 21 | 1995 | |
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| 5,770,194 Fibrin sealant compositions and methods for utilizing same | 6 | 1995 | |
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| 4,613,665 Process for covalent coupling for the production of conjugates, and polysaccharide containing products thereby obtained | 116 | 1983 | |
| 2006/0168,718 Urinal enclosure | 1 | 2006 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 3.5 Year Payment | $1600.00 | $800.00 | $400.00 | Jan 24, 2016 |
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Jan 24, 2020 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jan 24, 2024 |
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge - 3.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |