US Patent No: 8,226,945

Number of patents in Portfolio can not be more than 2000

Antibodies and immunoconjugates and uses therefor

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ALSO PUBLISHED AS: 20110142859
ATTORNEY / AGENT: (SPONSORED)
 

Importance

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Abstract

Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
GENENTECH, INC.SOUTH SAN FRANCISCO, CA2218

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ebens,, JR Allen J - 13 16
Gray, Alane M Brisbane, CA 7 49
Liang, Wei-Ching Foster City, CA 29 41
Wu, Yan Morganville, NJ 164 253
Yu, Shang-Fan Milpitas, CA 5 7

Cited Art

Patent Info (Count) # Cites Year
 
AMERICAN CYANAMID COMPANY (6)
4,970,198 Antitumor antibiotics (LL-E33288 complex) 12 1987
5,079,233 N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same 9 1989
5,606,040 Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group 7 1993
5,773,001 Conjugates of methyltrithio antitumor agents and intermediates for their synthesis 43 1994
5,739,116 Enediyne derivatives useful for the synthesis of conjugates of methyltrithio antitumor agents 19 1995
5,767,285 Linkers useful for the synthesis of conjugates of methyltrithio antitumor agents 15 1995
 
GENENTECH, INC. (5)
6,194,551 Polypeptide variants 117 1999
2004/0001,827 Serum albumin binding peptides for tumor targeting 6 2002
2005/0238,650 Compositions and methods for the treatment of tumor of hematopoietic origin 20 2004
2005/0276,812 Antibody-drug conjugates and methods 20 2005
2008/0050,310 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR 5 2007
 
IMMUNOGEN, INC. (4)
5,208,020 Cytotoxic agents comprising maytansinoids and their therapeutic use 98 1992
5,416,064 Cytotoxic agents comprising maytansinoids and their therapeutic use 69 1992
6,441,163 Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents 47 2001
2005/0169,933 Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates 16 2004
 
PROTEIN DESIGN LABS, INC. (2)
5,585,089 Humanized immunoglobulins 608 1995
5,693,762 Humanized immunoglobulins 468 1995
 
SEATTLE GENETICS, INC. (2)
2004/0018,194 Recombinant anti-CD30 antibodies and uses thereof 30 2003
2005/0238,649 Monomethylvaline compounds capable of conjugation to ligands 32 2004
 
TEIKOKU HORMONE MFG. CO., LTD. (2)
5,767,237 Peptide derivatives 26 1996
6,124,431 Peptide derivatives 22 1998
 
AMGEN INC. (1)
7,084,257 Fully human antibody Fab fragments with human interferon-gamma neutralizing activity 27 2001
 
BRISTOL-MYERS COMPANY (1)
4,975,278 Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells 177 1988
 
IMMUNOMEDICS, INC. (1)
5,789,554 Immunoconjugates and humanized antibodies specific for B-cell lymphoma and leukemia cells 46 1996
 
NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT (1)
2005/0244,828 Elisa assay of serum soluble cd22 to assess tumor burnden/relapse in subjects with leukemia and lymphoma 2 2004
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (2)
2009/0053,226 Compositions and methods for the treatment of tumor of hematopoietic origin 3 2008
2011/0045,005 COMPOSITIONS AND METHODS FOR THE TREATMENT OF TUMOR OF HEMATOPOIETIC ORIGIN 3 2010

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
GENENTECH, INC. (1)
8,394,607 Anti-CD22 antibodies and immunoconjugates and methods of use 0 2012

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