Pharmaceutical composition containing irbesartan
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United States of America Patent
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Jul 24, 2012
Grant Date -
Dec 8, 2005
app pub date -
Jun 2, 2005
filing date -
Jun 4, 2004
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention relates to pharmaceutical compositions containing irbesartan, providing oral formulations with a high relative amount or concentration of irbesartan. In one embodiment, the present invention provides an oral formulation of irbesartan containing greater than 70% w/w irbesartan. In another embodiment, the invention provides an oral formulation of irbesartan which exhibits a dissolution profile according to which greater than about 85% of the Irbesartan is dissolved within about 30 minutes using USP apparatus 2, placing the tablet in 1000 mL of 0.1N hydrochloric acid at 37° C. with paddle speed of 50 rpm. The formulation can optionally contain at least one additional active ingredient.
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