Targeted delivery to human diseases and disorders

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8231895
APP PUB NO 20090291049A1
SERIAL NO

12153649

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention provides a system presenting site-specific accumulation through a ligand that specifically targets a receptor overexpressed on the surface of specific cells within a target organ, like, for example, tumor cells and/or vascular cells of tumor blood vessels. Moreover, this invention provides a method where, upon internalization of the previous-mentioned system by the target cells, triggered release at a high rate of the associated agent takes place, permitting efficient intracellular delivery and, thus, increased concentration of the transported cargo at the target site. Overall, this invention provides a method for the diagnosis, prevention and treatment of human diseases and disorders.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
UNIVERSIDADE DE COIMBRAPAÇO DAS ESCOLAS COIMBRA 3004-531
CENTRO DE NEUROCIENCIAS E BIOLOGIA CELULARUNIVERSIDADE DE COIMBRA COIMBRA 3004-517

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Caldeira, de Moura Vera Lúcia Dantas Nunes Coimbra, PT 3 19
de, Almeida Moreira João Nuno Sereno Coimbra, PT 3 19
de, Magalhães Simões Sérgio Paulo Coimbra, PT 2 8
Pedroso, de Lima Maria da Conceição Monteiro Coimbra, PT 3 19

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation