Opioid agonist formulations with releasable and sequestered antagonist
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United States of America Patent
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Jul 31, 2012
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app pub date -
Mar 8, 2011
filing date -
Aug 6, 2001
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Abstract
Disclosed are oral dosage forms, comprising (i) a therapeutically effective amount of an opioid agonist; (ii) an opioid antagonist in releasable form; and (iii) a sequestered opioid antagonist which is not released when the dosage form is administered intact, and methods thereof.
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