Adhesive composition for carrying therapeutic agents as delivery vehicle on coatings applied to vascular grafts
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United States of America Patent
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Aug 7, 2012
Grant Date -
Jun 22, 2006
app pub date -
Jul 13, 2005
filing date -
Jul 13, 2004
priority date (Note) -
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Abstract
Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular grafts, are disclosed. Use of drug-coated vascular grafts is demonstrated for delivery of the therapeutic agents in vivo, thereby inhibiting restenosis or neointimal hyperplasia of the vascular graft and inhibiting infection at the vascular graft site. Methods of forming the adhesive and making the coated vascular grafts are also disclosed.
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