Method for reducing the weight of a subject or inhibiting weight gain in a subject
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United States of America Patent
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Aug 14, 2012
Grant Date -
Dec 16, 2010
app pub date -
Jan 7, 2010
filing date -
Dec 29, 2003
priority date (Note) -
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Abstract
Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively.
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