Depsipeptides and their therapeutic use

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United States of America Patent

PATENT NO 8247372
APP PUB NO 20100056434A1
SERIAL NO

12515880

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Abstract

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Compounds which are Spiruchostatin analogues of the general formula (I) or (I′), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF SOUTHAMPTONHIGHFIELD CAMPUS UNIVERSITY ROAD SOUTHAMPTON SO17 1BJ

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cecil, Alexander Richard Liam Hampshire, GB 17 136
Ganesan, Arasu Hampshire, GB 4 11
Packham, Graham Keith Wiltshire, GB 5 22

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