Modified carbocyanine dyes and their conjugates

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United States of America Patent

PATENT NO 8252932
APP PUB NO 20110171678A1
SERIAL NO

12906304

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Abstract

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Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are uniformly superior to those of conjugates of spectrally similar dyes wherein attachment is at a different position. The invention includes derivative compounds having one or more benzo nitrogens.

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Patent Owner(s)

  • LIFE TECHNOLOGIES CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheung, Ching-Ying San Ramon, US 56 986
Leung, Wai-Yee San Ramon, US 71 1857
Yue, Stephen Eugene, US 111 1452

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