Adenylyl cyclase antibodies, compositions and uses thereof
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United States of America Patent
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Sep 11, 2012
Grant Date -
Nov 6, 2008
app pub date -
May 26, 2005
filing date -
May 26, 2004
priority date (Note) -
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Abstract
The invention relates to compositions and methods for diagnosing and treating cardiac conditions and neurodegenerative diseases using antibodies which specifically recognize and bind to the adenylyl cyclase 5 isoform in the heart and brain. These antibodies demonstrate high specificity to the AC5 isoform and do not cross react to any other AC5 isoform. The invention further relates to methods of delivery of drugs to the site of injured tissue using the antibodies of the present invention.
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