Method for the synthesis of a ramipril intermediate

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Sep 11, 2012
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Oct 27, 2011
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Oct 27, 2009
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Oct 30, 2008

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Expired

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Abstract

The present invention relates to a process for the preparation of octahydrocyclopenta[b]pyrrole-2-carboxylic acid and esters thereof of general formula (1) in the presence of a cobalt and/or nickel comprising catalyst and to the use of compounds of general formula (1) in the synthesis of ramipril.

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DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B V	2613 AX DELFT

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C07D:HETEROCYCLIC COMPOUNDS

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Inventor Name	Address	# of filed Patents	Total Citations
De, Lange Ben	Munstergeleen, NL	28	8
Heemskerk, Dennis	Schinveld, NL	14	6

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Method for the synthesis of a ramipril intermediate

Number of patents in Portfolio can not be more than 2000

United States of America Patent

13126871

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PATENT NO	8263784
APP PUB NO	20110263871A1
SERIAL NO	13126871
DOCKET NO

US Family Size	Non-US Coverage
Patent Longevity Expired	Forward Citations

DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
September 11, 2012	US,8263784,B2 US8263784B2	GRANTED PATENT AS SECOND PUBLICATION
October 27, 2011	US,20110263871,A1 US20110263871A1	FIRST PUBLISHED PATENT APPLICATION

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13126871

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