Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids

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United States of America Patent

PATENT NO 8277823
SERIAL NO

12784821

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Abstract

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The present invention relates to liposome formulations that are physically stable. In particular the present invention relates to steric stabilization of cationic liposomes by incorporating glycolipids into the liposomes. The stabilized liposomes can be used either as an adjuvant for antigenic components or as a drug delivery system. In particular the invention relates to vaccines with adjuvants in aqueous media for immunization, where the final product is stable.

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Patent Owner(s)

  • STATENS SERUM INSTITUT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andersen, Peter Broenshoej, DK 73 970
Davidsen, Jesper Solroed Strand, DK 8 37
Rosenkrands, Ida Vaerloese, DK 16 112

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