Biopolymer sequencing by hybridization of probes to form ternary complexes and variable range alignment
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United States of America Patent
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Oct 2, 2012
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Apr 16, 2009
app pub date -
Oct 1, 2008
filing date -
Oct 1, 2007
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Abstract
Methods for sequencing a biopolymer by forming local ternary complexes along the length of the double-stranded biopolymer target molecule using one or more probes and obtaining information about the location of the probe(s) using a detector. These methods offer particular advantage when implemented with nanopore (including micropore) detection systems.
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