Methods and kits for the rapid determination of patients at high risk of death during severe sepsis and septic shock
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United States of America Patent
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Oct 9, 2012
Grant Date -
Apr 29, 2010
app pub date -
Oct 28, 2008
filing date -
Oct 28, 2008
priority date (Note) -
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Abstract
The present invention provides for the in vitro establishing of a prognosis for a subject in severe sepsis with at least two organ failures or in septic shock with at least two organ failures. Embodiments of the invention comprise the steps of measuring the level of the S100A8/A9 complex from a biological sample from a subject, and comparing the measured level to a predetermined threshold in which the measured level of the S100A8/A9 complex above the predetermined threshold is indicative of a bad prognosis and a measured level of the S100A8/A9 complex below the predetermined threshold is indicative of a good prognosis.
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