Process for synthesizing and purifying sucralose
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United States of America Patent
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Oct 9, 2012
Grant Date -
Nov 18, 2010
app pub date -
Dec 19, 2008
filing date -
Dec 19, 2007
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Abstract
The present invention discloses a process for synthesizing sucralose, which comprises reacting sucrose with acetic anhydride in the solvent of a N-amide compound in the presence of an organic complex alkali metal salt catalyst to produce sucrose-6-acetate, and then chlorinating and deacetylating the sucrose-6-acetate to give sucralose. The present invention also discloses a process for purifying sucralose, which comprises purifying crude sucralose with one or more organic solvents to obtain purified sucralose.
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