One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel

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United States of America Patent

PATENT NO 8293930
SERIAL NO

11630510

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Abstract

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A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction of protecting the C-7 and C-10 positions and attaching a side chain at the C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and taxane intermediates.

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Patent Owner(s)

  • CHATHAM BIOTEC, LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Naidu, Ragina Burnaby, CA 27 70

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