Integrated finite element and circulatory model for predicting hemodynamic effects of left ventricular impairment, resynchronization and remodeling

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United States of America Patent

PATENT NO 8295907
SERIAL NO

11778231

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Abstract

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A computational model which integrates a complex circulatory model and a finite element to determine the dynamics of a left ventricle continuously over consecutive cardiac cycles. The model includes determining a LV pressure (plv) using a circulatory model, using a finite element model plv as input and determining a LV volume (vlv), computing a LV elastance according to: elv=plv/vlv, driving the circulatory model with the elv; and returning to determining a LV pressure and starting the next iteration, wherein the steps continue at a sufficient time resolution for a desired number of entire cardiac cycles. The dynamic Young's modulus functions are assigned to individual finite elements, resulting in a time-varying left ventricular elastance that drives the circulatory model.

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Patent OwnerAddress
RHODE ISLAND BOARD OF EDUCATION STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS80 WASHINGTON STREET PROVIDENCE RI 02903

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chiaramida, Salvatore A Charleston, US 1 88
Dong, Rumei Kingston, US 1 88
Sun, Ying Wakefield, US 390 7529
Vetter, Frederick J South Kingston, US 1 88

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