Dissolution of arterial plaque

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8304383
APP PUB NO 20080187569A1
SERIAL NO

12024908

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Embodiments of methods of treating atherosclerosis are described. In some embodiments an emulsifier is provided to achieve levels in the systemic circulation that are effective to solubilize atherosclerotic plaque, resulting in plaque regression. In some embodiments, levels of greater than 50 μM are achieved; in some embodiments levels ranging from about 100 μM to about 600 μM are achieved; in some embodiments, levels ranging from about 100 μM to about 300 μM are achieved. Emulsifiers can include bile salts, saponins, and ionic, nonionic, and zwitterionic detergents, or salts, conjugates, hydrates, solvates, or polymorphs thereof. In some embodiments, a statin can be administered simultaneously or sequentially with an emulsifier.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
AHRO IP HOLDINGS LLCNEW YORK, NY3

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Zadini, Filiberto Camarillo, US 19 216
Zadini, Giorgio Camarillo, US 25 279

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (2)
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* 2005/0158,408 Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof 18 2004
 
CIFTCIOGLU, NEVA DR. (1)
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (1)
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KENSEY NASH CORPORATION (1)
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Vascular Designs, Inc. (1)
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THE UNIVERSITY OF BRITISH COLUMBIA (1)
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UNIVERSITY OF SASKATCHEWAN (1)
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CHILDREN'S HOSPITAL RESEARCH FOUNDATION (1)
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ANGIOTECH INTERNATIONAL AG (2)
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MEDICAL RESEARCH FOUNDATION OF OREGON, A NON-PROFIT CORP. OF OR. (1)
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IDEA AG (1)
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UNIVERSITY OF CHICAGO, THE (1)
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Z & Z MEDICAL HOLDINGS, INC. (5)
2006/0222,695 Deoxycholic acid liposome-based dermatological topical preparation 19 2005
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2007/0129,425 Dissolution of arterial cholesterol plaques by pharmacological preparation 2 2007
 
AHRO IP HOLDINGS LLC (1)
2008/0187,569 DISSOLUTION OF ARTERIAL PLAQUE 2 2008
 
CARDINAL HEALTH SWITZERLAND 515 GMBH (1)
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Noven Pharmaceuticals, Inc. (1)
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BOSTON SCIENTIFIC SCIMED, INC. (1)
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INNOVATIONAL HOLDINGS LLC (1)
2004/0143,322 Method and apparatus for treating vulnerable artherosclerotic plaque 67 2003
 
GP MEDICAL, INC. (1)
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DSM NUTRITIONAL PRODUCTS, INC. (1)
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MEDTRONIC VASCULAR, INC. (1)
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NAT CITY BANK OF MIDWEST (1)
2004/0151,716 Material and method for treating microbial mediated dermatological conditions 6 2004
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
PRODOTTI CHIMICI E ALIMENTARI S.P.A. (1)
9580458 Polymorphic form of sodium hyodeoxycholate (NaHDC) and its preparation process 0 2014
* Cited By Examiner

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