Intranasal compositions
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United States of America Patent
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Nov 13, 2012
Grant Date -
Sep 30, 2010
app pub date -
Nov 10, 2008
filing date -
Nov 9, 2007
priority date (Note) -
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Abstract
A liquid aqueous formulation for the intranasal administration of apomorphine includes:
- (a) at least about 15 mg/ml of apomorphine; and(b) a solubilising agent selected from (i) at least one polyoxyethylene-polyoxypropylene copolymer (poloxamer);(ii) at least one cyclodextrin; and(iii) at least one cyclodextrin together with chitosan.The formulations of the invention can be used in the treatment or management of Parkinson's disease and erectile dysfunction.
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