Process to prepare paliperidone and intermediates thereof
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United States of America Patent
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Nov 13, 2012
Grant Date -
May 26, 2011
app pub date -
May 28, 2009
filing date -
May 29, 2008
priority date (Note) -
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Abstract
The present invention relates to an improved process for obtaining Paliperidone, I, comprising alkylating compound VI, or a salt thereof, with compound V, or a salt thereof, using a base selected from triethylamine or diisopropylethylamine and, optionally, a solvent. Moreover, the invention relies on the preparation of intermediates used in such process.
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