Nucleic acids encoding antibodies having altered effector function and methods for making the same
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United States of America Patent
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Nov 27, 2012
Grant Date -
Apr 26, 2012
app pub date -
Dec 21, 2010
filing date -
Aug 22, 2003
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Abstract
The invention provides a method of producing aglycosylated Fc-containing polypeptides, such as antibodies, having desired effector function. The invention also provides aglycosylated antibodies produced according to the method as well as methods of using such antibodies as therapeutics.
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